2024
Emergent Large Vessel Occlusion due to Intracranial Stenosis: Identification, Management, Challenges, and Future Directions
Al Kasab S, Nguyen T, Derdeyn C, Yaghi S, Amin-Hanjani S, Kicielinski K, Zaidat O, de Havenon A. Emergent Large Vessel Occlusion due to Intracranial Stenosis: Identification, Management, Challenges, and Future Directions. Stroke 2024, 55: 355-365. PMID: 38252763, DOI: 10.1161/strokeaha.123.043635.Peer-Reviewed Original ResearchConceptsIntracranial atherosclerotic stenosisVessel occlusionRecurrence riskEarly recurrence riskHigh-risk patientsAggressive medical managementRecurrent stroke riskEndovascular therapyHemodynamic failureTreatment strategiesPerfusion imagingAdvanced ageEndovascular interventionIntracranial stenosisMedical managementRisk factorsHigh riskAdvanced imagingAtherosclerotic stenosisStroke riskOcclusionStenosisPatientsRisk
2023
Recurrence risk in symptomatic intracranial stenosis treated medically in the real world
Yaghi S, Shu L, Goldstein E, Chang A, Kala N, Stretz C, Burton T, Perelstein E, Furie K, Jayaraman M, Torabi R, Moldovan K, de Havenon A, Khatri P, Gebregziabher M, Liebeskind D, Prabhakaran S. Recurrence risk in symptomatic intracranial stenosis treated medically in the real world. Journal Of Stroke And Cerebrovascular Diseases 2023, 32: 107086. PMID: 37030126, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107086.Peer-Reviewed Original ResearchConceptsIntracranial atherosclerotic stenosisSymptomatic intracranial atherosclerotic stenosisClinical trialsRecurrence riskRecurrent strokeInclusion criteriaReal-world settingMaximal medical treatmentRecurrent stroke rateDual antiplatelet therapyAcute ischemic strokeReal-world cohortSymptomatic intracranial stenosisPharmacological treatment strategiesCox regression modelMeeting inclusion criteriaLow event ratesAntiplatelet therapyStroke RegistryIschemic eventsIschemic strokeWorld CohortHospitalized patientsEarly recurrenceIntracranial stenosis
2017
High-resolution vessel wall MRI for the evaluation of intracranial atherosclerotic disease
de Havenon A, Mossa-Basha M, Shah L, Kim SE, Park M, Parker D, McNally JS. High-resolution vessel wall MRI for the evaluation of intracranial atherosclerotic disease. Neuroradiology 2017, 59: 1193-1202. PMID: 28942481, DOI: 10.1007/s00234-017-1925-9.Peer-Reviewed Original ResearchConceptsHigh-resolution vessel wall MRIVessel wall MRIIntracranial atherosclerosisPrognosis of patientsIntracranial atherosclerotic diseasePost-contrast enhancementDiagnostic imaging techniquesHigh field strength MRIIschemic strokeStroke etiologyAtherosclerotic diseaseCerebrovascular diseaseVessel wall morphologyVascular pathologyIntracranial arteriesEnhancement patternRecurrence riskAtherosclerosisTranslational perspectiveVessel wallClinical interpretationMRIStrength MRIDisease