2020
Impact of Intracranial Pressure Monitor–Guided Therapy on Neurologic Outcome After Spontaneous Nontraumatic Intracranial Hemorrhage
Menacho ST, Grandhi R, Delic A, Anadani M, Ziai WC, Awad IA, Hanley DF, de Havenon A. Impact of Intracranial Pressure Monitor–Guided Therapy on Neurologic Outcome After Spontaneous Nontraumatic Intracranial Hemorrhage. Journal Of Stroke And Cerebrovascular Diseases 2020, 30: 105540. PMID: 33360250, PMCID: PMC8080544, DOI: 10.1016/j.jstrokecerebrovasdis.2020.105540.Peer-Reviewed Original ResearchMeSH KeywordsAgedClinical Trials, Phase III as TopicDatabases, FactualFemaleHumansIntracranial HemorrhagesIntracranial PressureMaleMiddle AgedMonitoring, PhysiologicPredictive Value of TestsRandomized Controlled Trials as TopicRecovery of FunctionRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeConceptsICP monitor placementNontraumatic intracranial hemorrhageIntracranial hemorrhageIntracranial pressure monitorPoor outcomeNeurologic outcomePressure monitorPropensity score-matched cohortMonitor placementIdentification of patientsSpontaneous intracranial hemorrhageExternal ventricular drainInvasive ICP monitoringLogistic regression modelsIntraparenchymal monitorsIII trialsSecondary outcomesPrimary outcomeBalanced cohortVentricular drainICP monitorICP monitoringPatientsSecondary analysisGreater risk
2019
End-of-Treatment Intracerebral and Ventricular Hemorrhage Volume Predicts Outcome
de Havenon A, Joyce E, Yaghi S, Ansari S, Delic A, Taussky P, Alexander M, Tirschwell D, Grandhi R. End-of-Treatment Intracerebral and Ventricular Hemorrhage Volume Predicts Outcome. Stroke 2019, 51: 652-654. PMID: 31842688, PMCID: PMC7000178, DOI: 10.1161/strokeaha.119.028199.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhage volumeIntracerebral hemorrhageClot evacuationHemorrhage volumeBetter outcomesVolume scoreInvasive clot evacuationMISTIE III trialSurgical clot evacuationGood neurological outcomePotential clinical benefitNeurological outcomeIII trialsPrimary outcomeClinical benefitHematoma volumePoor outcomeFunctional outcomeSurgical armICH sizeTherapeutic planningSecondary analysisPatientsStrong associationStratification scale