2014
A translational investigation targeting stress-reactivity and prefrontal cognitive control with guanfacine for smoking cessation
McKee SA, Potenza MN, Kober H, Sofuoglu M, Arnsten A, Picciotto MR, Weinberger AH, Ashare R, Sinha R. A translational investigation targeting stress-reactivity and prefrontal cognitive control with guanfacine for smoking cessation. Journal Of Psychopharmacology 2014, 29: 300-311. PMID: 25516371, PMCID: PMC4376109, DOI: 10.1177/0269881114562091.Peer-Reviewed Original ResearchConceptsPlacebo-treated subjectsFunctional magnetic resonance imagingCentral noradrenergic pathwaysPrefrontal cognitive dysfunctionSystolic blood pressureClinical outcome dataAd libitum smokingNovel translational approachStress-induced reinstatementMagnetic resonance imagingNicotine-deprived smokersBlood pressureNoradrenergic pathwaysAgonist guanfacineCognitive dysfunctionTreatment periodTobacco cravingQuit attemptsOutcome dataSmokingComplete abstinenceCortisol levelsTranslational investigationsCigarette useGuanfacine
2010
Perceived risks and benefits of quitting smoking in non-treatment seekers
Weinberger AH, Mazure CM, McKee SA. Perceived risks and benefits of quitting smoking in non-treatment seekers. Addiction Research & Theory 2010, 18: 456-463. PMID: 23662097, PMCID: PMC3646261, DOI: 10.3109/16066350903145072.Peer-Reviewed Original ResearchNon-treatment seekersExpectations of successDaily cigarette smokersNegative affectTreatment motivationExpected successSelf-EsteemQuit motivationMotivationEducation differencesAbstinentComplete abstinenceQuittingCigarette smokersAffectGreaterCravingExpectationsDifficultiesConfidenceEsteemAbstinenceBeliefsSmokersMeasures