Featured Publications
Preoccupation in bulimia nervosa, binge‐eating disorder, anorexia nervosa, and higher weight
Lydecker JA, Simpson L, Smith SR, White MA, Grilo CM. Preoccupation in bulimia nervosa, binge‐eating disorder, anorexia nervosa, and higher weight. International Journal Of Eating Disorders 2021, 55: 76-84. PMID: 34713460, PMCID: PMC8963447, DOI: 10.1002/eat.23630.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyBinge-eating disorderShape/weightStudy groupBulimia nervosaAnorexia nervosaFood/eatingDisorder treatment outcomesEating-disorder featuresCognitive behavioral therapyHigher body weightFood/Treatment outcomesBody weightHW groupWeb-based surveyFormal diagnosisOvert behavioral featuresNervosaDepressionDisordersSignificant differencesWeight preoccupationPsychopathologyEatingPsychiatric comorbidity as predictor and moderator of binge-eating disorder treatment outcomes: an analysis of aggregated randomized controlled trials
Lydecker JA, Grilo CM. Psychiatric comorbidity as predictor and moderator of binge-eating disorder treatment outcomes: an analysis of aggregated randomized controlled trials. Psychological Medicine 2021, 52: 4085-4093. PMID: 33849682, PMCID: PMC8514588, DOI: 10.1017/s0033291721001045.Peer-Reviewed Original ResearchBinge-eating disorderBinge-eating frequencyEating-disorder psychopathologyPsychiatric comorbidityBED treatment outcomesCognitive behavioral therapySelf-report measuresModerators of outcomeBinge-eating remissionDisorder treatment outcomesBehavioral weight lossRandomized-controlled trialCurrent psychiatric comorbidityMore effective interventionsTreatment outcomesAnxiety disordersTreatment researchSemi-structured interviewsMood comorbiditiesControl conditionPsychopathologyEffective interventionsComorbidity effectsWeight lossCurrent studyExamining sex as a predictor and moderator of treatment outcomes for binge‐eating disorder: Analysis of aggregated randomized controlled trials
Lydecker JA, Gueorguieva R, Masheb R, White MA, Grilo CM. Examining sex as a predictor and moderator of treatment outcomes for binge‐eating disorder: Analysis of aggregated randomized controlled trials. International Journal Of Eating Disorders 2019, 53: 20-30. PMID: 31497876, PMCID: PMC6983351, DOI: 10.1002/eat.23167.Peer-Reviewed Original ResearchConceptsBinge-eating disorderEating-disorder psychopathologyCognitive behavioral therapySelf-report measuresModerators of outcomeTreatment outcomesBehavioral weight lossStatistical Manual-Fourth EditionSignificant moderatorWeight lossControl conditionModeratorCourse of treatmentBetter treatment outcomesGreater weight lossMain effectStructured interviewsTreatment settingsPsychopathologyMultimodal treatmentPatient groupRCT studiesMedical CenterBed treatmentParticipantsExamining Race as a Predictor and Moderator of Treatment Outcomes for Binge-Eating Disorder: Analysis of Aggregated Randomized Controlled Trials
Lydecker JA, Gueorguieva R, Masheb R, White MA, Grilo CM. Examining Race as a Predictor and Moderator of Treatment Outcomes for Binge-Eating Disorder: Analysis of Aggregated Randomized Controlled Trials. Journal Of Consulting And Clinical Psychology 2019, 87: 530-540. PMID: 31008634, PMCID: PMC6589831, DOI: 10.1037/ccp0000404.Peer-Reviewed Original ResearchConceptsBinge-eating disorderWhite participantsCognitive behavioral therapySelf-report measuresTreatment outcomesBinge-eating remissionModerate treatment outcomeBinge Eating DisorderBinge-eating episodesMain effectBlack participantsWeight lossBehavioral weight lossEvidence-based treatmentsLower depressionTreatment researchRandomized Controlled TrialsBetter treatment outcomesControl conditionParticipantsControlled TrialsMultimodal treatmentPercent weight lossPatient groupModeratorFood insecurity and bulimia nervosa in the United States
Lydecker JA, Grilo CM. Food insecurity and bulimia nervosa in the United States. International Journal Of Eating Disorders 2019, 52: 735-739. PMID: 30920683, PMCID: PMC6555671, DOI: 10.1002/eat.23074.Peer-Reviewed Original ResearchI didn't want them to see: Secretive eating among adults with binge‐eating disorder
Lydecker JA, Grilo CM. I didn't want them to see: Secretive eating among adults with binge‐eating disorder. International Journal Of Eating Disorders 2019, 52: 153-158. PMID: 30623972, PMCID: PMC6368878, DOI: 10.1002/eat.23002.Peer-Reviewed Original ResearchConceptsBody mass indexBinge-eating disorderEating-disorder psychopathologyObjective binge-eating episodesSecretive eatingBinge-eating episodesGreater eating-disorder psychopathologyGreater body mass indexHigher depression scoresClinical characteristicsMass indexTreatment-seeking adultsDepression scoresPatientsShape/weightWeight concernsAdultsEatingSelf-report measuresDisordersShape concernsEpisodesGreater proportionPsychopathologyTreatment formulationForm and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder
Lydecker JA, White MA, Grilo CM. Form and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder. Journal Of Consulting And Clinical Psychology 2017, 85: 1095-1103. PMID: 29083224, PMCID: PMC5679782, DOI: 10.1037/ccp0000258.Peer-Reviewed Original ResearchConceptsBody image variablesBody image disturbanceBody image constructsBinge-eating disorderImage constructImage variablesWeight/shape overvaluationBinge-eating frequencyInvestigator-based interviewBiopsychosocial featuresEating-disorder psychopathologyTreatment-seeking patientsShape preoccupationShape dissatisfactionShape overvaluationShape concernsCore aspectsCurrent studyTreatment formulationConstructsImportant distinctionDifferent aspectsOvervaluationPreoccupationDisordersDoes your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape
Lydecker JA, Grilo CM. Does your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape. Preventive Medicine 2017, 105: 265-270. PMID: 28987340, PMCID: PMC5659758, DOI: 10.1016/j.ypmed.2017.10.009.Peer-Reviewed Original ResearchConceptsWeight/shapeParental overvaluationPersonal weightEating-disorder psychopathologyBinge-eating disorderEating PsychopathologyParent psychopathologyPediatric obesityDearth of researchChild weightCross-sectional designParental attitudesPsychopathologyImportant psychopathologyDisorder treatmentCross-sectional studyParentsCurrent studyIntegral stakeholdersWeight influenceOvervaluationClinical attentionChild BMIChild healthRelated conceptsChildren of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight
Lydecker JA, Grilo CM. Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight. International Journal Of Eating Disorders 2016, 50: 648-656. PMID: 27859458, PMCID: PMC5429220, DOI: 10.1002/eat.22648.Peer-Reviewed Original ResearchConceptsBinge-eating disorderChild weightChildren's bingeEating-disorder psychopathologyHigher child weightCross-sectional findingsChild overweightProspective confirmationChildren's eatingChild feedingChild overeatingDietary restrictionObesityClinical interventionsPrevention effortsEating Disorder BehaviorsDisordersBingePreliminary evidencePotential factorsEatingCurrent studyLimited literatureCore featuresOBFathers and mothers with eating-disorder psychopathology: Associations with child eating-disorder behaviors
Lydecker JA, Grilo CM. Fathers and mothers with eating-disorder psychopathology: Associations with child eating-disorder behaviors. Journal Of Psychosomatic Research 2016, 86: 63-69. PMID: 27302549, PMCID: PMC4911698, DOI: 10.1016/j.jpsychores.2016.05.006.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyEating-disordered behaviorChild body mass index (BMI) z-scoreBody mass index z-scoreSample of parentsChild feeding difficultiesCore eating disorder psychopathologyIndex z-scoreBinge-eating disorderParental feeding practicesEating Disorder PsychopathologyFeeding difficultiesChild weightChildren's dietsChildren's eatingMaternal concernClinical concernFeeding practicesBulimia nervosaEating Disorder BehaviorsAnorexia nervosaZ-scorePsychosocial causesClinical interventionsClinical programsCognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial
Grilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial. International Journal Of Eating Disorders 2023, 56: 1544-1553. PMID: 37144325, PMCID: PMC10524840, DOI: 10.1002/eat.23975.Peer-Reviewed Original ResearchConceptsInitial acute treatmentBinge-eating disorderCognitive behavioral therapyAcute treatmentBinge-eating frequencyInitial interventionTherapist-led cognitive behavioural therapyInitial pharmacological treatmentTreat remission ratesEvidence-based treatmentsSingle-site trialAcute efficacyRemission rateAdult patientsInitial treatmentPharmacological treatmentPatientsPosttreatment assessmentBehavioral treatmentSufficient benefitTherapyDisordersInterventionTreatmentPharmacotherapy
2024
Reliability of the original and brief versions of the Eating Disorder Examination in binge‐eating disorder
Lydecker J, Ivezaj V, Wiedemann A, Kerrigan S, Grilo C. Reliability of the original and brief versions of the Eating Disorder Examination in binge‐eating disorder. Obesity 2024, 32: 702-709. PMID: 38311600, PMCID: PMC10965370, DOI: 10.1002/oby.23993.Peer-Reviewed Original ResearchEating Disorder ExaminationEating Disorder Examination interviewEating-disorder psychopathologyBinge-eating disorderInternal consistencyDoctoral-levelIndicators of loss of controlInterrater reliabilityLoss of controlBinge eatingBinge-eating episodesPsychological treatmentPsychometric propertiesPsychometric studyTests of reliabilityBehavioral indicatorsAssessed adultsClinical researchPsychopathologyEatingRatersDisordersAudio-recordedAdultsPatient groupThe children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating
Lydecker J, Ozbardakci E, Grilo C. The children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating. International Journal Of Eating Disorders 2024, 57: 745-751. PMID: 38308384, PMCID: PMC10947894, DOI: 10.1002/eat.24153.Peer-Reviewed Original ResearchBinge-eating disorderBinge eatingDisordered eating behaviorsEating behaviorsSecretive eatingParent changesDisordered eatingAssociated with disordered eating behaviorsEating-disorder psychopathologyEnd-of-treatment assessmentParental eating disordersAssociated with changesChildren of parentsCross-sectional workChild disordered eating behaviorsBinge-eating frequencyEating disordersSchool-aged childrenParental treatmentUntreated family membersParent medicationLongitudinal researchBingeBaseline assessmentEating
2023
The Relationship of Self-identified Weight Status With Perceived Mental and Physical Health
Hamilton A, Smith S, Lydecker J. The Relationship of Self-identified Weight Status With Perceived Mental and Physical Health. Journal Of Psychiatric Practice 2023, 29: 430-438. PMID: 37948168, PMCID: PMC10653675, DOI: 10.1097/pra.0000000000000744.Peer-Reviewed Original ResearchConceptsOW/OBBinge-eating disorderDisorder psychopathologyPhysical healthMental healthStudy groupBulimia nervosaOW/OB groupBN groupOverweight/obesityFuture clinical researchOB groupWeight statusObesityClinical researchBED groupOverweightDepressionHealthPsychopathologyDisordersGroupOBLow levelsAnalysis of varianceNaltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reductionNaltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial
Grilo C, Lydecker J, Gueorguieva R. Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2023, 53: 7775-7784. PMID: 37366017, PMCID: PMC10751383, DOI: 10.1017/s0033291723001800.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderBinge-eating remissionAcute treatmentMaintenance treatmentBinge-eating frequencyDouble-blind placebo-controlled trialBehavioral weight loss therapyWeight lossCo-occurring obesitySuccessful acute treatmentPlacebo-controlled trialWeight loss therapySignificant additional weight lossSingle-site trialAdditional weight lossAcute efficacyRemission rateAdult patientsComorbid obesityBupropionInitial interventionPosttreatment assessmentRespondersPlaceboLoss of control in binge‐eating disorder: Fear and resignation
Perelman H, Gilbert K, Grilo C, Lydecker J. Loss of control in binge‐eating disorder: Fear and resignation. International Journal Of Eating Disorders 2023, 56: 1199-1206. PMID: 36920120, PMCID: PMC10247475, DOI: 10.1002/eat.23929.Peer-Reviewed Original ResearchConceptsBinge-eating disorderCognitive-affective experiencesLoss of controlModerate treatment outcomeBinge-eating episodesEating-disorder psychopathologyTreatment-seeking patientsFuture researchAbsence of fearGreater distressPsychopathologyFearSevere psychopathologyResearch cliniciansSemistructured interviewsTreatment formulationPast monthDisordersResignationTreatment outcomesExperienceBlack individualsEmotionsTreatment planningIndividuals
2022
Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial
Grilo CM, Lydecker JA, Fineberg SK, Moreno JO, Ivezaj V, Gueorguieva R. Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial. American Journal Of Psychiatry 2022, 179: 927-937. PMID: 36285406, PMCID: PMC9722598, DOI: 10.1176/appi.ajp.20220267.Peer-Reviewed Original ResearchConceptsBehavioral weight loss therapyBinge-eating disorderPlacebo groupBupropion groupWeight lossRandomized double-blind placebo-controlled trialDouble-blind placebo-controlled trialLogistic regressionBinge-eating remissionPlacebo-controlled trialWeight loss therapyDouble-blind placeboSerious public health problemPublic health problemEvidence-based treatmentsRate of participantsBinge-eating frequencyBinge Eating DisorderMedical comorbiditiesRemission rateLoss therapyPercent weight lossMixed modelsFunctional impairmentSecondary measures
2020
Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study
Grilo CM, Lydecker JA, Morgan PT, Gueorguieva R. Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study. Clinical Therapeutics 2020, 43: 112-122.e1. PMID: 33218742, PMCID: PMC7902424, DOI: 10.1016/j.clinthera.2020.10.010.Peer-Reviewed Original ResearchConceptsBinge-eating disorderEating-disorder psychopathologyPilot RCTTreatment of BEDOutcome time pointDouble-blind treatmentPercentage of patientsControlled Pilot StudyDiscontinuation of medicationTreatment of bingeEvidence-based treatmentsBinge-eating frequencyBupropion combinationAdult patientsAdverse eventsComorbid obesitySecondary outcomesPrimary outcomeAcute effectsFunctional impairmentPlaceboLong-term effectsPatientsMost outcomesObesityTesting the Validity and Clinical Utility of the Severity Specifiers for Binge-Eating Disorder for Predicting Treatment Outcomes
Lydecker JA, Ivezaj V, Grilo CM. Testing the Validity and Clinical Utility of the Severity Specifiers for Binge-Eating Disorder for Predicting Treatment Outcomes. Journal Of Consulting And Clinical Psychology 2020, 88: 172-178. PMID: 31894997, PMCID: PMC7286612, DOI: 10.1037/ccp0000464.Peer-Reviewed Original ResearchConceptsBinge-eating disorderCognitive behavioral therapyBehavioral weight lossSeverity specifiersSelf-report measuresTreatment-seeking individualsBinge-eating frequencyBinge Eating DisorderEating-disorder psychopathologyClinical utilityTreatment outcomesSeverity categoriesPredicting Treatment OutcomeWeight lossFuture researchMain effectDepression scoresStatistical ManualParticipantsTesting treatmentsMultimodal treatmentPharmacological treatmentTreatment responseMedical CenterLarge series