2018
BDNF Val66Met polymorphism and posttraumatic stress symptoms in U.S. military veterans: Protective effect of physical exercise
Pitts BL, Whealin JM, Harpaz-Rotem I, Duman RS, Krystal JH, Southwick SM, Pietrzak RH. BDNF Val66Met polymorphism and posttraumatic stress symptoms in U.S. military veterans: Protective effect of physical exercise. Psychoneuroendocrinology 2018, 100: 198-202. PMID: 30388593, DOI: 10.1016/j.psyneuen.2018.10.011.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmino Acid SubstitutionBrain-Derived Neurotrophic FactorCase-Control StudiesExerciseFemaleHumansMaleMethionineMiddle AgedMilitary PersonnelPolymorphism, Single NucleotideProtective FactorsResilience, PsychologicalSeverity of Illness IndexStress Disorders, Post-TraumaticUnited StatesValineVeteransConceptsMet allele carriersBDNF Val66Met polymorphismAllele carriersVal66Met polymorphismPhysical exerciseGreater severityPTSD symptomsU.S. military veteransTrauma burdenBrain-derived neurotrophic factor (BDNF) Val66Met polymorphismPast-month PTSD symptomsNeurotrophic factor Val66Met polymorphismMilitary veteransLifetime trauma burdenHigh trauma burdenVal/ValAdrenal (HPA) axis reactivityPosttraumatic stress disorder (PTSD) symptomsBDNF releaseCurrent PTSD symptomsProtective effectRe-experiencing symptomsAxis reactivityPosttraumatic stress symptomsSymptoms
2017
Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Mota NP, Han S, Harpaz‐Rotem I, Maruff P, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH. Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Depression And Anxiety 2017, 35: 168-177. PMID: 29172227, PMCID: PMC5794529, DOI: 10.1002/da.22698.Peer-Reviewed Original ResearchConceptsΕ4 allele carriersApolipoprotein E gene polymorphismE gene polymorphismTrauma burdenU.S. military veteransAllele carriersPosttraumatic stress disorderPTSD symptomsNational HealthGreater social supportGene polymorphismsGreater severityMilitary veteransVeterans StudyAPOE ε4 carrier statusSocial supportΕ4 carrier statusAPOE genotypeΕ4 noncarriersPosttraumatic stress symptomsIndependent replication sampleSymptomsPTSD riskStress disorderCarrier status
2013
POSTTRAUMATIC STRESS DISORDER AMONG PRESCHOOLERS EXPOSED TO ONGOING MISSILE ATTACKS IN THE GAZA WAR
Kaufman‐Shriqui V, Werbeloff N, Faroy M, Meiri G, Shahar DR, Fraser D, Novack Y, Bilenko N, Vardi H, Elhadad N, Pietrzak RH, Harpaz‐Rotem I. POSTTRAUMATIC STRESS DISORDER AMONG PRESCHOOLERS EXPOSED TO ONGOING MISSILE ATTACKS IN THE GAZA WAR. Depression And Anxiety 2013, 30: 425-431. PMID: 23620192, DOI: 10.1002/da.22121.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderOnly significant risk factorOngoing missile attacksChild posttraumatic stress disorderSignificant risk factorsYoung childrenPsychosomatic reactionsRisk factorsMaternal anxietyPosttraumatic stress symptomsSociodemographic characteristicsMothers of preschoolersStress disorderPsychosomatic correlatesMothersChildrenPsychosomatic symptomatologyStress symptomsHigh ratePreschool childrenTraumaDisordersMissile attacksTraumatic experiencesConstipation
2012
Examining the relation between combat-related concussion, a novel 5-factor model of posttraumatic stress symptoms, and health-related quality of life in Iraq and Afghanistan veterans.
Tsai J, Whealin JM, Scott JC, Harpaz-Rotem I, Pietrzak RH. Examining the relation between combat-related concussion, a novel 5-factor model of posttraumatic stress symptoms, and health-related quality of life in Iraq and Afghanistan veterans. The Journal Of Clinical Psychiatry 2012, 73: 1110-8. PMID: 22781019, DOI: 10.4088/jcp.11m07587.Peer-Reviewed Original ResearchConceptsMental health-related qualityHealth-related qualityPersistent postconcussive symptomsCombat-related concussionPostconcussive symptomsAlcohol use problemsPTSD symptomsAfghanistan veteransPhysical health-related qualityForm Health SurveyDysphoric arousal symptomsUse problemsIraq/Afghanistan veteransStrongest predictorPosttraumatic stress disorder (PTSD) symptomsClinical characteristicsProgram registryHealth SurveyPsychiatric cliniciansPosttraumatic stress symptomsMultivariate analysisSymptomsConcussionBivariate analysisSymptomatic veterans
2011
Support for a novel five-factor model of posttraumatic stress symptoms in three independent samples of Iraq/Afghanistan veterans: A confirmatory factor analytic study
Pietrzak RH, Tsai J, Harpaz-Rotem I, Whealin JM, Southwick SM. Support for a novel five-factor model of posttraumatic stress symptoms in three independent samples of Iraq/Afghanistan veterans: A confirmatory factor analytic study. Journal Of Psychiatric Research 2011, 46: 317-322. PMID: 22154134, DOI: 10.1016/j.jpsychires.2011.11.013.Peer-Reviewed Original ResearchConceptsIraq/Afghanistan veteransHyperarousal symptom clustersConfirmatory factor analytic studyFactor analytic studiesAfghanistan veteransDysphoric arousalPTSD symptomsArousal clustersCommunity samplePosttraumatic stress disorder (PTSD) symptomsEmotional numbing modelSymptom clustersTreatment-seeking samplePosttraumatic stress symptomsDSM-IV modelIndependent samplesFive-factor modelConfirmatory factor analysisAnxious arousalEmotional numbingNumbing modelPTSD symptomatologyDisorder symptomsStress symptomsPTSD Checklist