2024
Lisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial
Grilo C, Ivezaj V, Yurkow S, Tek C, Wiedemann A, Gueorguieva R. Lisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2024, 54: 3334-3344. PMID: 39258475, PMCID: PMC11496227, DOI: 10.1017/s003329172400148x.Peer-Reviewed Original ResearchEating-disorder psychopathologyBinge-eating disorderMaintenance treatmentAcute treatmentBinge-eating remission ratesCognitive-behavioral therapyEfficacy of lisdexamfetamineSignificant weight gainDouble-blind placebo-controlled trialAcute respondersLisdexamfetamine treatmentPsychopathological outcomesPosttreatment assessmentLisdexamfetaminePlacebo-controlled trialRandomized double-blind placebo-controlled trialSingle-site trialAssociated with significant weight lossPsychopathologyBinge-eatingRemission rateWeight lossPlaceboRelapse rateControl researchOvervaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder
Grilo C, Ivezaj V, Gueorguieva R. Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder. International Journal Of Eating Disorders 2024, 57: 1268-1273. PMID: 38321617, PMCID: PMC11093697, DOI: 10.1002/eat.24141.Peer-Reviewed Original ResearchOvervaluation of shape/weightEating-disorder psychopathologyBinge-eating disorderEating Disorder Examination interviewBeck Depression InventoryWeight loss treatmentClinical overvaluationBinge-eating frequencyDiagnostic specifierBinge eatingNon-abstinenceExamination interviewDepression InventoryShape/weightDepression scoresFollow-upPsychopathologyAbstinenceBingeDepressionClinical implicationsDepression 1PosttreatmentDisordersOvervaluationReliability of the original and brief versions of the Eating Disorder Examination in binge‐eating disorder
Lydecker J, Ivezaj V, Wiedemann A, Kerrigan S, Grilo C. Reliability of the original and brief versions of the Eating Disorder Examination in binge‐eating disorder. Obesity 2024, 32: 702-709. PMID: 38311600, PMCID: PMC10965370, DOI: 10.1002/oby.23993.Peer-Reviewed Original ResearchEating Disorder ExaminationEating Disorder Examination interviewEating-disorder psychopathologyBinge-eating disorderInternal consistencyDoctoral-levelIndicators of loss of controlInterrater reliabilityLoss of controlBinge eatingBinge-eating episodesPsychological treatmentPsychometric propertiesPsychometric studyTests of reliabilityBehavioral indicatorsAssessed adultsClinical researchPsychopathologyEatingRatersDisordersAudio-recordedAdultsPatient group
2023
Binge-Eating Disorder Interventions: Review, Current Status, and Implications
Grilo C, Juarascio A. Binge-Eating Disorder Interventions: Review, Current Status, and Implications. Current Obesity Reports 2023, 12: 406-416. PMID: 37439970, PMCID: PMC10528223, DOI: 10.1007/s13679-023-00517-0.Peer-Reviewed Original ResearchConceptsPsychological treatmentSpecific psychological treatmentsEating-disorder psychopathologyEvidence-based treatmentsAdditional pharmacological optionsDisorder interventionsSerious psychiatric problemsBehavioral lifestyle interventionScalable interventionsEffective interventionsFuture researchCBTPsychiatric problemsBingeMixed outcomesInterventionCBTgshModest weight lossRecent findingsResearchPsychopathologyShameLifestyle interventionPharmacological optionsSubstantial morbidityLoss of control in binge‐eating disorder: Fear and resignation
Perelman H, Gilbert K, Grilo C, Lydecker J. Loss of control in binge‐eating disorder: Fear and resignation. International Journal Of Eating Disorders 2023, 56: 1199-1206. PMID: 36920120, PMCID: PMC10247475, DOI: 10.1002/eat.23929.Peer-Reviewed Original ResearchConceptsBinge-eating disorderCognitive-affective experiencesLoss of controlModerate treatment outcomeBinge-eating episodesEating-disorder psychopathologyTreatment-seeking patientsFuture researchAbsence of fearGreater distressPsychopathologyFearSevere psychopathologyResearch cliniciansSemistructured interviewsTreatment formulationPast monthDisordersResignationTreatment outcomesExperienceBlack individualsEmotionsTreatment planningIndividuals
2017
Driven exercise in the absence of binge eating: Implications for purging disorder
Lydecker JA, Shea M, Grilo CM. Driven exercise in the absence of binge eating: Implications for purging disorder. International Journal Of Eating Disorders 2017, 51: 139-145. PMID: 29215743, PMCID: PMC5796839, DOI: 10.1002/eat.22811.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyClinical significancePhysical activityCompensatory behaviorsBinge-eating episodesAbsence of bingeEating Disorder PsychopathologyLower depression levelsLow-frequency thresholdsWeb-based surveyDepression levelsSmall sample sizeHigher depressionOverall frequencyLaxativesTreatment researchMost domainsExerciseBingePsychopathologyDisordersDepressionParticipantsSimilar levelsFurther supportDoes your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape
Lydecker JA, Grilo CM. Does your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape. Preventive Medicine 2017, 105: 265-270. PMID: 28987340, PMCID: PMC5659758, DOI: 10.1016/j.ypmed.2017.10.009.Peer-Reviewed Original ResearchConceptsWeight/shapeParental overvaluationPersonal weightEating-disorder psychopathologyBinge-eating disorderEating PsychopathologyParent psychopathologyPediatric obesityDearth of researchChild weightCross-sectional designParental attitudesPsychopathologyImportant psychopathologyDisorder treatmentCross-sectional studyParentsCurrent studyIntegral stakeholdersWeight influenceOvervaluationClinical attentionChild BMIChild healthRelated conceptsCorrelates of weight-related quality of life among individuals with binge eating disorder before and after cognitive behavioral therapy
Mason TB, Crosby RD, Kolotkin RL, Grilo CM, Mitchell JE, Wonderlich SA, Crow SJ, Peterson CB. Correlates of weight-related quality of life among individuals with binge eating disorder before and after cognitive behavioral therapy. Eating Behaviors 2017, 27: 1-6. PMID: 28843136, PMCID: PMC5700842, DOI: 10.1016/j.eatbeh.2017.08.001.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyED psychopathologyBody mass indexWeight-related qualityBehavioral therapyEnd of treatmentSelf-report measuresPhysical functionSubjective bingeDisorder psychopathologyPublic distressPsychosocial variablesLongitudinal associationsPsychosocial factorsPsychopathologyNumber of EDsCopingBingeCurrent studyMass indexAvailable treatmentsDistressPredictor variablesFollowing associationsWeight lossRumination in Patients with Binge‐Eating Disorder and Obesity: Associations with Eating‐Disorder Psychopathology and Weight‐bias Internalization
Wang SB, Lydecker JA, Grilo CM. Rumination in Patients with Binge‐Eating Disorder and Obesity: Associations with Eating‐Disorder Psychopathology and Weight‐bias Internalization. European Eating Disorders Review 2017, 25: 98-103. PMID: 28078784, PMCID: PMC5318238, DOI: 10.1002/erv.2499.Peer-Reviewed Original ResearchConceptsShape/weightWeight bias internalizationEating-disorder psychopathologyBinge-eating disorderCognitive processesGreater eating-disorder psychopathologyImportant cognitive processesOvervaluation of shapeGreater weight bias internalizationHierarchical multiple regressionTreatment-seeking patientsGreater ruminationRuminationDiscrimination experiencesPhysical healthPsychopathologyNegative attitudesMultiple regressionOvervaluationObesity treatmentComorbid obesityAttitudesDisordersExperienceFindings
2015
Family histories of anxiety in overweight men and women with binge eating disorder: A preliminary investigation
Blomquist KK, Grilo CM. Family histories of anxiety in overweight men and women with binge eating disorder: A preliminary investigation. Comprehensive Psychiatry 2015, 62: 161-169. PMID: 26343481, PMCID: PMC4583821, DOI: 10.1016/j.comppsych.2015.07.007.Peer-Reviewed Original ResearchConceptsPsychological functioningAnxiety disordersDisorder psychopathologyBED patientsDevelopment of bingeDSM-IV anxiety disordersBattery of questionnairesMood disordersLifetime diagnosisSubstance use disordersComorbid anxietyBingeAnxietyDiagnostic InterviewFunctioningUse disordersPsychopathologyPreliminary findingsPreliminary examinationInterview methodFamily historyDisordersParticipantsOverweight patientsPreliminary investigation
2014
Overvaluation of shape and weight as a mediator between self-esteem and weight bias internalization among patients with binge eating disorder
Pearl RL, White MA, Grilo CM. Overvaluation of shape and weight as a mediator between self-esteem and weight bias internalization among patients with binge eating disorder. Eating Behaviors 2014, 15: 259-261. PMID: 24854815, PMCID: PMC4053161, DOI: 10.1016/j.eatbeh.2014.03.005.Peer-Reviewed Original ResearchConceptsOvervaluation of shapeWeight bias internalizationWeight Bias Internalization ScaleRosenberg Self-Esteem ScaleBinge-eating frequencyWeight biasMediation analysisShape/weightTreatment-seeking individualsSelf-Esteem ScaleInternalization ScaleSemi-structured interviewsBingeOvervaluationClinical effortsDisordersPsychopathologyBiasSupportRelationshipScaleIndividualsImplicationsSignificant correlationWeight contributesCurrent and emerging drug treatments for binge eating disorder
Reas DL, Grilo CM. Current and emerging drug treatments for binge eating disorder. Expert Opinion On Emerging Drugs 2014, 19: 99-142. PMID: 24460483, PMCID: PMC4026932, DOI: 10.1517/14728214.2014.879291.Peer-Reviewed Original ResearchConceptsPsychological interventionsDisorder psychopathologyWeight lossCognitive behavioral therapyCertain medicationsBinge Eating DisorderBehavioral weight lossCombination of medicationsEating DisordersBingeDrug treatmentLong-term effectsMedicationsAssociated depressionTreatment studiesPsychopathologyBED outcomesPhase IIInterventionOutcomesDepressionTrialsDisordersRemissionPharmacotherapy
2012
Night eating in obese treatment‐seeking hispanic patients with and without binge eating disorder
Grilo CM, Milsom VA, Morgan PT, White MA. Night eating in obese treatment‐seeking hispanic patients with and without binge eating disorder. International Journal Of Eating Disorders 2012, 45: 787-791. PMID: 22407481, PMCID: PMC3378792, DOI: 10.1002/eat.22011.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyHispanic patientsMetabolic variablesBed statusNon-NE groupNon-NE patientsFrequency of nightConsecutive seriesPatientsHispanic menSpanish-language versionDepression levelsDisorder psychopathologyMonolingual SpanishGroup differencesPsychopathologyDepressionGreater frequencyDisorders
2011
An examination of the food addiction construct in obese patients with binge eating disorder
Gearhardt AN, White MA, Masheb RM, Morgan PT, Crosby RD, Grilo CM. An examination of the food addiction construct in obese patients with binge eating disorder. International Journal Of Eating Disorders 2011, 45: 657-663. PMID: 22684991, PMCID: PMC3375872, DOI: 10.1002/eat.20957.Peer-Reviewed Original ResearchConceptsYale Food Addiction ScaleDisorder psychopathologyFood addictionBED patientsConfirmatory factor analysisFood addiction constructEmotion dysregulationNegative affectOne-factor solutionYFAS scoresAssociated psychopathologyAddiction constructPsychopathologyPsychometric propertiesAddiction ScaleBingeInternalized weight bias in obese patients with binge eating disorder: Associations with eating disturbances and psychological functioning
Durso LE, Latner JD, White MA, Masheb RM, Blomquist KK, Morgan PT, Grilo CM. Internalized weight bias in obese patients with binge eating disorder: Associations with eating disturbances and psychological functioning. International Journal Of Eating Disorders 2011, 45: 423-427. PMID: 21717488, PMCID: PMC3184343, DOI: 10.1002/eat.20933.Peer-Reviewed Original ResearchConceptsTreatment-seeking obese patientsDisorder psychopathologyWeight biasFat phobiaInternalized weight biasSignificant independent contributionPsychological functioningExamination interviewCommunity sampleBED patientsPhobiaPsychopathologyWidespread biasIndependent contributionBingeDepressionIWBBiasDisordersHigh levelsObese personsFunctioningScoresVarianceCorrelatesThe mediational significance of negative/depressive affect in the relationship of childhood maltreatment and eating disorder features in adolescent psychiatric inpatients
Hopwood CJ, Ansell EB, Fehon DC, Grilo CM. The mediational significance of negative/depressive affect in the relationship of childhood maltreatment and eating disorder features in adolescent psychiatric inpatients. Eating And Weight Disorders - Studies On Anorexia, Bulimia And Obesity 2011, 16: 9-16. PMID: 21727786, PMCID: PMC3646630, DOI: 10.1007/bf03327515.Peer-Reviewed Original ResearchConceptsAdolescent psychiatric inpatientsChildhood maltreatmentPsychiatric inpatientsDisorder featuresDepressive affectBody-related psychopathologyRisk factorsDisorder psychopathologyType of maltreatmentAssessment BatteryInpatientsMen/boysAdolescent boysBoysMaltreatmentPsychopathologyGirlsMediation effect
2010
Personality heterogeneity in female adolescent inpatients with features of eating disorders
Hopwood CJ, Ansell EB, Fehon DC, Grilo CM. Personality heterogeneity in female adolescent inpatients with features of eating disorders. Comprehensive Psychiatry 2010, 51: 585-591. PMID: 20965304, PMCID: PMC2962865, DOI: 10.1016/j.comppsych.2010.03.006.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAggressionAlcoholismAnorexia NervosaBody ImageBulimiaBulimia NervosaCluster AnalysisComorbidityDefense MechanismsFemaleHumansImpulsive BehaviorInternal-External ControlMood DisordersPatient AdmissionPersonality DisordersPersonality InventoryPsychometricsReproducibility of ResultsSelf ConceptSocial ConformitySubstance-Related DisordersConceptsImportant clinical implicationsDisorder featuresFemale adolescent inpatientsDisturbed eatingMood dysfunctionPersonality heterogeneityClinical implicationsAdult womenClinical useComorbid psychopathologyAdolescent inpatientsPersonality variabilitySubstance useDisorder symptomsAdolescent girlsFunctioning groupMood psychopathologyEatingHigh functioningDifferent personality modelsExternalizing groupWomenPrevious evidencePsychopathology
2008
The construct validity of rule-breaking and aggression in an adult clinical sample
Hopwood CJ, Burt SA, Markowitz JC, Yen S, Shea MT, Sanislow CA, Grilo CM, Ansell EB, McGlashan TH, Gunderson JG, Zanarini MC, Skodol AE, Morey LC. The construct validity of rule-breaking and aggression in an adult clinical sample. Journal Of Psychiatric Research 2008, 43: 803-808. PMID: 18789456, PMCID: PMC2696696, DOI: 10.1016/j.jpsychires.2008.07.008.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAggressionAntisocial Personality DisorderComorbidityCompulsive Personality DisorderFemaleHumansImpulsive BehaviorInterview, PsychologicalMaleMichiganMiddle AgedPersonalityPersonality AssessmentPsychiatric Status Rating ScalesRisk FactorsSocial DesirabilitySubstance-Related DisordersSuicideYoung AdultConceptsAdult clinical sampleAntisocial behaviorObsessive-compulsive personality disorderPersonality disorderClinical samplesCluster B personality disordersGender moderation effectConcurrent psychopathologyProspective behaviorB personality disordersPersonality traitsModeration effectSeparable componentsMeaningful correlatesLow conscientiousnessAggressionDifferent etiological mechanismsConstruct validityPrevious researchConscientiousnessCurrent studyPsychopathologySuicide riskEtiological mechanismsDisorders
2001
Subtyping Binge Eating Disorder
Grilo C, Masheb R, Wilson G. Subtyping Binge Eating Disorder. Journal Of Consulting And Clinical Psychology 2001, 69: 1066-1072. PMID: 11777111, DOI: 10.1037/0022-006x.69.6.1066.Peer-Reviewed Original ResearchConceptsDietary-negative affect subtypeIndividual differencesStable individual differencesPure dietary subtypeEating-related psychopathologyCluster analytic studyEating DisordersPsychological disturbancesTime points 4 weeksAffective disturbancesBulimia nervosaModerate dietingSignificant consistencySubtyping approachSubset of casesDisordersPsychopathologyCluster analysisDietingNervosaSubtypesPatientsSubtypingCorrelates of community violence exposure in hospitalized adolescents
Fehon D, Grilo C, Lipschitz D. Correlates of community violence exposure in hospitalized adolescents. Comprehensive Psychiatry 2001, 42: 283-290. PMID: 11458302, DOI: 10.1053/comp.2001.24580.Peer-Reviewed Original ResearchConceptsCommunity violence exposureCommunity violenceViolence exposurePost-traumatic stress disorder symptomsSelf-report instrumentDisorder symptomsExternalizing psychopathologyAdolescent inpatientsBehavioral correlatesChildhood maltreatmentSexual assaultPhysical assaultViolence potentialChildren's exposurePerpetrators of violenceAdolescentsDrug useVictimsCorrelatesAssaultViolenceInternalizingPatientsPsychopathologyTraumatization