1986
Evidence for electroneutral sodium chloride transport in rat proximal convoluted tubule
Howlin KJ, Alpern RJ, Berry CA, Rector FC. Evidence for electroneutral sodium chloride transport in rat proximal convoluted tubule. American Journal Of Physiology 1986, 250: f644-f648. PMID: 3963204, DOI: 10.1152/ajprenal.1986.250.4.f644.Peer-Reviewed Original ResearchConceptsTransepithelial potential differenceLate proximal tubular fluidProximal tubular fluidNaCl transportEffect of cyanideLumen-negative potential differenceSodium chloride transportLuminal perfusateTubular fluidNaCl absorptionTwo-thirdsTubulesPotential differenceChloride transportActive transportPerfusate
1985
Amiloride inhibition of proximal tubular acidification
Howlin KJ, Alpern RJ, Rector FC. Amiloride inhibition of proximal tubular acidification. American Journal Of Physiology 1985, 248: f773-f778. PMID: 2988347, DOI: 10.1152/ajprenal.1985.248.6.f773.Peer-Reviewed Original ResearchConceptsProximal tubular acidificationLuminal amilorideBicarbonate absorptionX minTubular acidificationM amilorideSodium chloride absorptionLate proximal tubular fluidProximal tubular fluidPerfusion rateProximal acidificationVivo microperfusionTubular fluidKidney cortexChloride absorptionInhibition of acidificationPmol xAmilorideNonspecific inhibitionAmiloride inhibitionGreater inhibitionBrush border membrane vesiclesInhibitionGlucose effluxPotent inhibitor