2021
Data-independent acquisition-based proteome and phosphoproteome profiling across six melanoma cell lines reveals determinants of proteotypes
Gao E, Li W, Wu C, Shao W, Di Y, Liu Y. Data-independent acquisition-based proteome and phosphoproteome profiling across six melanoma cell lines reveals determinants of proteotypes. Molecular Omics 2021, 17: 413-425. PMID: 33728422, PMCID: PMC8205956, DOI: 10.1039/d0mo00188k.Peer-Reviewed Original Research
2015
Multiplexed Targeted Mass Spectrometry-Based Assays for the Quantification of N‑Linked Glycosite-Containing Peptides in Serum
Thomas SN, Harlan R, Chen J, Aiyetan P, Liu Y, Sokoll LJ, Aebersold R, Chan DW, Zhang H. Multiplexed Targeted Mass Spectrometry-Based Assays for the Quantification of N‑Linked Glycosite-Containing Peptides in Serum. Analytical Chemistry 2015, 87: 10830-10838. PMID: 26451657, PMCID: PMC4708883, DOI: 10.1021/acs.analchem.5b02063.Peer-Reviewed Original ResearchMeSH KeywordsAgedChromatography, LiquidGlycosylationHumansMaleMass SpectrometryMiddle AgedPeptidesProstatic NeoplasmsConceptsGlycosite-containing peptidesClinical Proteomic Tumor Analysis ConsortiumParallel reaction monitoringNational Cancer Institute's Clinical Proteomic Tumor Analysis ConsortiumCommon protein modificationsProtein glycosylationProtein modificationBiological functionsAnalysis ConsortiumRelative abundanceTargeted Mass SpectrometryPRM assaysRobust assayPeak area ratioRelative peak area ratiosGlycoproteinReaction monitoringAssaysHuman serumMass spectrometryDisease statesPeptidesProstate cancer patient seraMS assayGlycosylation
2012
Integrative Proteomics and Tissue Microarray Profiling Indicate the Association between Overexpressed Serum Proteins and Non-Small Cell Lung Cancer
Liu Y, Luo X, Hu H, Wang R, Sun Y, Zeng R, Chen H. Integrative Proteomics and Tissue Microarray Profiling Indicate the Association between Overexpressed Serum Proteins and Non-Small Cell Lung Cancer. PLOS ONE 2012, 7: e51748. PMID: 23284758, PMCID: PMC3526638, DOI: 10.1371/journal.pone.0051748.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerTissue microarray analysisCell lung cancerLung cancerLung cancer patientsPotential serum biomarkersSerum proteinsBlood levelsCancer deathCancer patientsSerum biomarkersTissue microarray profilingAlpha 1BTumor sectionsSignificant associationCancerEarly detectionSerum proteomics datasetMultiple reaction monitoringPatientsMicroarray profilingLabel-free quantitative proteomicsAbnormal biological processesHealthy casesMicroarray analysis