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Past Seminars

2023-2024

Lingjun Li

Thursday, June 27th, 2024
Advancing Biomedical Research via Innovation in Mass Spectrometry (MS)-based Approaches
Professor
University of Wisconsin-Madison
Hosted by: Dr. Yansheng Liu

Onyema Ogbuago

Thursday, June 20th, 2024
One small molecule, ample applications: clinical development of a versatile novel HIV-1 capsid inhibitor”
Associate Professor
Yale School of Medicine
Hosted by: Dr. Mark Lemmon

Jonathan Abraham

Thursday, June 13th, 2024
Alphavirus interactions with cellular receptors”
Associate Professor
Harvard Medical School
Hosted by: Dr. Daryl Klein

Vijay Sankaran

Thursday, June 6th, 2024
Genetic Studies of Human Hematopoiesis”
Associate Professor
Harvard Medical School
Hosted by: Dr. Mark Lemmon

Ning Zheng

Thursday, May 16th, 2024
Targeted Protein Degradation: From Mechanisms to Therapeutics”
Professor
University of Washington
Hosted by: Dr. Wei Mi

Margaret Stratton

Thursday, May 9th, 2024
“Allosteric regulation of CaMKII mediates long-term memory and fertilization”
Associate Professor
University of Massachusetts, Amherst
Hosted by: Dr. Benjamin Turk

Randy Stockbridge

Thursday, April 4th, 2024
“The molecular basis of antiseptic transport and resistance”
Associate Professor
University of Michigan
Hosted by: Dr. Gary Rudnick

Inga Haenelt

Thursday, March 21st, 2024
Bacterial Stress Resistance - How Bacteria cope with drastically changing Environments”
Professor
Goethe-University Frankfurt
Hosted by: Dr. Gary Rudnick

Roberto Domingez

Thursday, March 7th, 2024
Cryo-EM structures reveal the secrets of actin monomer addition/dissociation at the ends of the actin filament”
Professor
University of Pennsylvania
Hosted by: Dr. Kathryn Ferguson

Ron Dror

Thursday, February 22nd, 2024
Achieving fine control of receptor function via learning and simulation of 3D structure”
Professor
Stanford University
Hosted by: Dr. Assaf Alon

Gary Rudnick

Thursday, Feb 8th, 2024
Conformational Change in Neurotransmitter Transporters: Roles in Ion-Substrate Coupling and Drug Design”
Professor Emeritus
Yale University
Hosted by: Dr. Benjamin Turk

Teresa Palomero

Thursday, January 25th, 2024
Unraveling Mechanisms of Transformation in Peripheral T-cell Lymphoma”
Professor
Columbia University
Hosted by: Dr. Elias Lolis

Benjamin Turk

Thursday, January 11th, 2024
Decoding Protein Kinase Signaling Networks”
Associate Professor
Yale University
Hosted by: Dr. Mark Lemmon

Gabriel Lander

Thursday, December 14th, 2023
Do we still need crystallography? A cryoEM case study in targeted protein degradation”
Professor
Scripps Research
Hosted by: Dr. Wei Mi

Ben Garcia

Thursday, December 7th, 2023
Quantitative mass spectrometry for understanding epigenetic mechanisms in human disease”
Professor
Washington University School of Medicine
Hosted by: Dr. Yansheng Liu

Brian Shiochet

Thursday, November 30th, 2023
“Following the Rabbit into Chemical Space”
Professor
University of California, San Francisco
Hosted by: Pharmacology Graduate Students

Eileen White

Thursday, November 16th, 2023
Cancer Metabolism and Immunity”
Professor
Rutgers Cancer Institute of New Jersey
Hosted by: Dr. Claudio Alarcon

Claudio Alarcon

Thursday, November 9th, 2023
Exploring the Role of RNA Modifications in Normal Physiology and Cancer”
Assistant Professor
Yale University
Hosted by: Dr. Mark Lemmon

Goutham Narla

Thursday, November 2nd, 2023
From mutations to small molecules: lessons learned from Protein Phosphatase 2A”
Professor
University of Michigan
Hosted by: Dr. Benjamin Turk

John Scott

Thursday, October 19th, 2023
Exploring and Exploiting the Spatial Constraints of Protein Kinase Signaling”
Professor
University of Washington School of Medicine
Hosted by: Dr. Benjamin Turk

Philip King

Thursday, September 14th, 2023
Communication between the EPHB4 receptor tyrosine kinase and the RASA1 Ras GTPase-activating protein in the development and function of the blood and lymphatic vasculatures"
Professor
University of Michigan
Hosted by: Dr. Titus Boggon

2022-2023

Dr. Yamuna Krishnan
Thursday, June 22nd, 2023
“Intracellular Electrophysiology"
Professor
University of Chicago
Hosted by: Dr. Moitrayee Bhattacharyya

Dr. Sebastian Klinge
Thursday, June 8th, 2023
“Witnessing ribosome assembly in human cells"
Associate Professor
The Rockefeller University
Hosted by: Dr. Claudio Alarcon

Dr. Michael Grabe
Thursday, May 25th, 2023
“Structural insight into sugar transport by SGLTs”
Professor
University of California, San Francisco
Hosted by: Dr. Gary Rudnick

Dr. Tamir Gonen
Thursday, May 11th, 2023
“Quo Vadis MicroED”
Professor of Biological Chemistry and Physiology
University of California, Los Angeles
Hosted by: Dr. Moitrayee Bhattacharyya

Dr. Filippo Mancia
Thursday, April 20th, 2023
“The molecular mechanisms underlying cellular uptake of vitamin A”
Professor, Associate Vice Chair
Columbia University
Hosted by: Dr. Wei Mi

Dr. Stacy Malaker
Thursday, April 13th, 2023
“Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE”
Assistant Professor of Chemistry
Yale University
Hosted by: Dr. Karen Anderson

Dr. Jean Schwarzbauer
Thursday, March 30th, 2023
“Fibronectin matrix assembly and its dysregulation in fibrosis”
Eugene Higgins Professor of Molecular Biology
Princeton University
Hosted by: Dr. David Calderwood

Dr. Steve Rutherford
Thursday, March 9th, 2023
“The outer membrane of Gram-negative bacteria as an antibacterial target”
Principal Scientist
Genentech
Hosted by: Dr. Wei Mi

Dr. Jun Huh
Thursday, February 23rd, 2023
“Immune modulatory roles of microbial metabolites of bile acids”
Associate Professor of Microbiology and Immunobiology
Harvard Medical School
Hosted by: Dr. Joel Butterwick

Dr. Benjamin Goult
Thursday, February 2nd, 2023
“The MeshCODE theory – does our brain store memories in binary format?”
Professor of Biochemistry
University of Kent
Hosted by: Dr. David Calderwood

Dr. Lydia Finley
Thursday, January 26th, 2023
“Metabolic regulation of cell fate transitions”
Associate Member, Cell Biology Program
Memorial Sloan Kettering Cancer Center
Hosted by: Dr. Kathryn Ferguson

Dr. Tom Rapoport
Thursday, January 19th, 2023
“Protein import into peroxisomes reveals new paradigms of protein translocation across membranes”
Professor
Harvard Medical School
Hosted by: Dr. Wei Mi

Dr. Diane Lidke
Thursday, December 15th, 2022“Single Molecule Imaging Provides New Insights into Oncogenic EGFR Signaling”
Professor
University of New Mexico
Cancer Research Facility
Hosted by: Dr. Mark Lemmon

Dr. Mark Peifer
Thursday, December 1st, 2022
“Building the Body Plan: The Miracle of Morphogenesis”
Michael Hooker Distinguished Professor
University of North Carolina
Chapel Hill
Hosted by: Dr. David Calderwood

Dr. Poulikos Poulikakos
Thursday, November 17th, 2022
“Targeting Oncogenic Signaling for Cancer Therapy from Resistance Mechanisms to Novel Strategies”
Associate Professor
The Tisch Cancer Institute
Icahn School of Medicine at Mount Sinai
Hosted by: Dr. Elias Lolis

Dr. Kun-Liang Guan
Thursday, November 10th, 2022
“The Hippo Pathway: Signaling and Cancer”
Distinguished Professor of Pharmacology
University of California
Hosted by: Dr. Benjamin Turk

Dr. Matthew Potthoff
Thursday, November 3rd, 2022
“Endocrine Control of Nutrient and Energy Homeostasis by the Liver”
Roy J. Carver Associate Professor in Neuroscience
and Pharmacology
University of Iowa
Hosted by: Dr. Sangwon Lee

Dr. Gilead Barnea
Thursday, October 20th, 2022
“The Tango toolkit for trans-synaptic tracing and manipulation of neural circuits”
Sidney A. Fox and Dorothea Doctors Fox Professor
of Ophthalmology, Visual Sciences, and Neuroscience
Brown University
Hosted by: Dr. Joseph Schlessinger and Irit Lax

Dr. Steve Almo
Thursday, September 22, 2022
“Selectivity in Biology and Therapeutics”
Professor of Biochemistry
Albert Einstein College of Medicine
Hosted by: Dr. Elias Lolis and Dr. Karen Anderson

2021-2022

Dr. Ryan E. Hibbs
Thursday June 16th
“Structural mechanisms of ion channel gating, pharmacology, and CNS immune disorders”
Associate Professor
University of Texas Southwestern Medical Center
Hosted by Dr. Joel Butterwick

Dr. Wolfgang Peti
Thursday June 9th
“Function and Selectivity of Protein Phosphatases”
Professor and Department Chair
University of Connecticut Health Center
Hosted by Dr. Titus Boggon

Dr. John Kuriyan
Thursday May 19th
“Activation of the EGF Receptor”
Professor of Molecular & Cell Biology and Chemistry
University of California, Berkeley
Hosted by Dr. Leonard Kaczmarek

Dr. Rachelle Gaudet
Thursday May 12th
“Mechanics of an Nramp-Family Transition Metal Transporter”
Professor of Molecular and Cellular Biology
Harvard University
Hosted by Dr. Gary Rudnick

Dr. Florentine Rutaganira
Thursday April 28th
“Probing the Origin of Cell Communication in Animals”
Assistant Professor of Biochemistry & Developmental Biology,
Stanford University
Hosted by Dr. Elias Lolis

Dr. Minglei Zhao
Thursday April 21st
“Structural insights into Ubr1 mediated N-degron polyubiquitination”
Assistant Professor
University of Chicago
Hosted by Wei Mi

Dr. Yifan Cheng
Thursday April 14th
“Single particle cryo-EM of TRPV1: from atomic structure to gating mechanism”
Professor, HHMI Investigator
University of California San Francisco
Hosted by Dr. Wei Mi

Dr. Natalie Ahn
Thursday March 31st
“The importance of protein dynamics for kinase activation and inhibitor design: The case of ERK2”
Distinguished Professor
University of Colorado at Boulder
Hosted by Dr. Benjamin Turk

Dr. Donita Brady
Thursday March 24th
“Cellular and Molecular Determinants of Copper Activation of Protein Kinases in Cancer”
Associate Professor
University of Pennsylvania
Hosted by Dr. Mark Lemmon

Dr. Klaus Hahn
Thursday March 17th
“Spatio-temporal control of GTPase signaling revealed by new optogenetic, biosensor and single molecule imaging tools”
Thurman Distinguished Professor
UNC-Chapel Hill
Hosted by Dr. David Calderwood

Dr. Natalia Jura
Thursday March 10th
“HER2 and HER3 receptor tyrosine kinases - together in sickness and in health”
Associate Professor
University of California, San Francisco
Hosted by Dr. Kathryn Ferguson

Dr. Michael Eck
Thursday Feb. 24th
“Structural insights into the regulation and pharmacology of Ras/MAP kinase pathway”
Assistant Vice Chancellor for Health Sciences Faculty Affairs; University of California, San Diego
Hosted by Pharmacology Graduate Students

Dr. Jared Toettcher
Thursday Feb. 17th
“Signaling, illuminated: moving proteins and assembling organelles to crack the signaling code”
Associate Professor of Molecular Biology
Hosted by Dr. Mark Lemmon

Dr. Paolo Picotti
Thursday, Jan. 3rd
“Proteomes in 3D: Structural barcodes to probe protein functional alterations”
Deputy head of Institute for Molecular Systems Biology
Hosted by Dr. Yansheng Liu

Dr. Avery D. Posey
Thursday, Dec. 9th
"Chimeric antigen receptor T-cells and carbohydrate-based cancer targets"
Assistant Professor of Pharmacology; University of Pennsylvania
Hosted by Pharmacology Postdocs

Dr. Marc N. Wein
Thursday Dec. 2nd
“Signal transduction pathways that control osteocyte differentiation and function”.
Assistant Professor of Medicine, Massachusetts General Hospital, Harvard Medical School
Hosted by Dr. Joseph Schlessinger

Dr. JoAnn Trejo
Thursday, Nov. 18th
“Cell Signaling by Protease-activated Receptors”
Assistant Vice Chancellor for Health Sciences Faculty Affairs; University of California, San Diego
Hosted by Dr. Joel Butterwick

Dr. Jason Cai
Thursday, Nov. 11th
“PET Imaging in Disease Diagnosis and Drug Development”
Assistant Professor of Radiology and Biomedical Imaging; Yale University
Hosted by Dr. Elias Lolis

Dr. Maria Lehtinen
Thursday, Nov. 4th
“Illuminating the choroid plexus - cerebrospinal fluid system in health and disease”
Neuroscientist and Associate Professor; Harvard Medical School
Hosted by Dr. Leonard Kaczmarek

Dr. Cyril Zipfel
Thursday, Oct. 21st
“Regulation of plant receptor kinase-mediated immunity”
Chair of Molecular and Cellular Plant Physiology; University of Zurich
Hosted by Dr. Kathryn Ferguson

Dr. Lewis Kay
Thursday, Oct. 14th
“The importance of dynamics in the function and misfunction of molecular machines”
Professor, Biochemistry; University of Toronto
Hosted by Dr. Sangwon Lee

Dr. Mart Loog
Thursday, Sept. 23rd
“Temporal control of CDK signaling via multi-site phosphorylation”
Head of Laboratory, Professor of Molecular Systems Biology; University of Tartu
Hosted by Dr. Benjamin Turk

Dr. Hoang Duong (Kelly) Nguyen
Thursday, Sept. 16th
“Replenishing the ends: Visualization of human telomerase holoenzyme by cryo-EM”
Group Leader MRC Laboratory of Molecular; Biology University of Cambridge
Hosted by Dr. Sangwon Lee

Dr. Maria Sibilia
Thursday, Sept. 9th
“Microenvironmental Drivers of Inflammation and Tumorigenesis”
University Professor; Medical University of Vienna
Hosted by Dr. Irit Lax

Dr. Dirk Slotboom
Thursday, Sept. 2nd
“Interplay between the lipid bilayer and transport proteins in membrane transport processes”
Professor in Biochemistry
University of Groningen, The Netherlands
Hosted by Gary Rudnick