1999
Bound‐solvent structures for microgravity‐, ground control‐, gel‐ and microbatch‐grown hen egg‐white lysozyme crystals at 1.8 Å resolution
Dong J, Boggon T, Chayen N, Raftery J, Bi R, Helliwell J. Bound‐solvent structures for microgravity‐, ground control‐, gel‐ and microbatch‐grown hen egg‐white lysozyme crystals at 1.8 Å resolution. Acta Crystallographica Section D, Structural Biology 1999, 55: 745-752. PMID: 10089304, DOI: 10.1107/s0907444998016047.Peer-Reviewed Original ResearchConceptsHen egg white lysozymeX-ray dataAdvanced Protein Crystallization FacilityDifferent crystallization methodsLysozyme crystalsCrystal growth environmentProtein structureHen egg-white lysozyme crystalsEgg white lysozymeCrystallization methodProtein crystalsGelÅ resolutionCrystalsMicrogravity Spacelab (LMS) missionCrystallizationCrystallization FacilityAgarose gelStructureDiffusion methodPhase boundaryPhysics statesOilNumber of methodsLysozyme
1997
CCD Video Observation of Microgravity Crystallization of Lysozyme and Correlation with Accelerometer Data
Snell E, Boggon T, Helliwell J, Moskowitz M, Nadarajah A. CCD Video Observation of Microgravity Crystallization of Lysozyme and Correlation with Accelerometer Data. Acta Crystallographica Section D, Structural Biology 1997, 53: 747-755. PMID: 11540584, DOI: 10.1107/s0907444997007968.Peer-Reviewed Original ResearchPartial Improvement of Crystal Quality for Microgravity‐Grown Apocrustacyanin C1
Snell E, Cassetta A, Helliwell J, Boggon T, Chayen N, Weckert E, Hölzer K, Schroer K, Gordon E, Zagalsky P. Partial Improvement of Crystal Quality for Microgravity‐Grown Apocrustacyanin C1. Acta Crystallographica Section D, Structural Biology 1997, 53: 231-239. PMID: 15299925, DOI: 10.1107/s0907444996013996.Peer-Reviewed Original ResearchPartial improvement of crystal quality for microgravity-grown apocrustacyanin C1.
Snell E, Cassetta A, Helliwell J, Boggon T, Chayen N, Weckert E, Holzer K, Schroer K, Gordon E, Zagalsky P. Partial improvement of crystal quality for microgravity-grown apocrustacyanin C1. Acta Crystallographica Section D, Structural Biology 1997, 53: 231-9. PMID: 11540431.Peer-Reviewed Original Research
1996
Trends and Challenges in Experimental Macromolecular Crystallography
Chayen N, Boggon T, Cassetta A, Deacon A, Gleichmann T, Habash J, Harrop S, Helliwell J, Nieh Y, Peterson M, Raftery J, Snell E, Hädener A, Niemann A, Siddons D, Stojanoff V, Thompson A, Ursby T, Wulff M. Trends and Challenges in Experimental Macromolecular Crystallography. Quarterly Reviews Of Biophysics 1996, 29: 227-278. PMID: 8968112, DOI: 10.1017/s0033583500005837.Peer-Reviewed Original ResearchConceptsHuman genome sequencing projectGenome sequencing projectsModern drug discoveryStructural molecular biologyPrimary sequencingYeast genomeBiological chemistryStructural chemistrySequencing projectsBiological macromoleculesStructural DatabaseRational designMolecular biologyCognate ligandsDrug discoveryMolecular interactionsEnzyme reactivityMacromolecular crystallographyNovel inhibitorsChemistryNucleic acidsVirus structureFunctional detailsStructural detailsPharmaceutical industry