2009
Fat Embolism
Akhtar S. Fat Embolism. Anesthesiology Clinics 2009, 27: 533-550. PMID: 19825491, DOI: 10.1016/j.anclin.2009.07.018.Peer-Reviewed Original ResearchConceptsFat embolism syndromeFat embolismProgressive respiratory insufficiencyHours of injuryPetechial rashClinical sequelaeRespiratory insufficiencyClinical presentationSerious manifestationsMental statusOrthopedic injuriesClinical signsLung microcirculationEmbolismPathologic consequencesInjuryFat dropletsRashSequelaePrognosisPathophysiologySyndromeEtiologyInsufficiencyMicrocirculation
2007
An Inflammatory Pathway of IFN-γ Production in Coronary Atherosclerosis
Ranjbaran H, Sokol SI, Gallo A, Eid RE, Iakimov AO, D’Alessio A, Kapoor JR, Akhtar S, Howes CJ, Aslan M, Pfau S, Pober JS, Tellides G. An Inflammatory Pathway of IFN-γ Production in Coronary Atherosclerosis. The Journal Of Immunology 2007, 178: 592-604. PMID: 17182600, DOI: 10.4049/jimmunol.178.1.592.Peer-Reviewed Original ResearchConceptsIL-12/ILIFN-gamma-inducible chemokinesCoronary atherosclerosisIL-12IL-18IFN-gammaPlasma levelsT cellsTh1-type cytokine productionHuman atherosclerotic coronary arteriesAcute coronary syndromeSubset of patientsHuman coronary atherosclerosisTh1-type cytokinesC-reactive proteinIFN-γ productionElevated plasma levelsPlasma of patientsInnate immune responseAtherosclerotic coronary arteriesCoronary syndromeSystemic inflammationCardiac catheterizationCardiopulmonary bypassGamma secretion