2022
Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65
Schonberger RB, Dai F, Michel G, Vaughn MT, Burg MM, Mathis M, Kheterpal S, Akhtar S, Shah N, Bardia A. Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65. Journal Of Clinical Anesthesia 2022, 80: 110846. PMID: 35489305, PMCID: PMC11150018, DOI: 10.1016/j.jclinane.2022.110846.Peer-Reviewed Original ResearchConceptsPropofol induction doseGeneral anesthetic inductionSevere hypotensionInduction doseBlood pressure measurementsYears of ageSurgical patientsEndotracheal intubationAnesthetic inductionInvasive blood pressure measurementsGeriatric surgical patientsNon-vascular surgeryDose of propofolNon-invasive blood pressure measurementBlood pressure dropSignificant independent associationPostoperative morbidityRetrospective observationalTotal patientsMulticenter cohortPrimary outcomeAnesthesia inductionPrimary exposureIndependent associationSurgical incision
2006
Ischemic Heart Disease
Akhtar S. Ischemic Heart Disease. Anesthesiology Clinics 2006, 24: 461-485. PMID: 17240602, DOI: 10.1016/j.atc.2006.04.002.Peer-Reviewed Original ResearchConceptsLee Cardiac Risk IndexACC/AHA guidelinesPerioperative cardiac riskPreoperative coronary revascularizationStructured management protocolCardiac Risk IndexPostoperative myocardial injuryIntraoperative anesthetic managementIschemic heart diseaseAlpha-2 agonistsLong-term outcomesRole of biomarkersNumber of patientsCoronary revascularizationNoncardiac surgeryPerioperative morbidityPostoperative morbidityAHA guidelinesAnesthetic managementCardiac riskPostoperative managementPostoperative phaseRisk stratificationMyocardial injuryHemodynamic control