2013
Oral Antimycobacterial Therapy in Chronic Cutaneous Sarcoidosis: A Randomized, Single-Masked, Placebo-Controlled Study
Drake WP, Oswald-Richter K, Richmond BW, Isom J, Burke VE, Algood H, Braun N, Taylor T, Pandit KV, Aboud C, Yu C, Kaminski N, Boyd AS, King LE. Oral Antimycobacterial Therapy in Chronic Cutaneous Sarcoidosis: A Randomized, Single-Masked, Placebo-Controlled Study. JAMA Dermatology 2013, 149: 1040-1049. PMID: 23863960, PMCID: PMC3927541, DOI: 10.1001/jamadermatol.2013.4646.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdultAgedAnti-Bacterial AgentsAzithromycinCD4-Positive T-LymphocytesChronic DiseaseDrug Therapy, CombinationEthambutolFemaleFollow-Up StudiesHumansLevofloxacinMaleMiddle AgedOfloxacinRifampinSarcoidosisSeverity of Illness IndexSingle-Blind MethodSkin DiseasesTranscriptomeTreatment OutcomeYoung AdultConceptsChronic cutaneous sarcoidosisCutaneous sarcoidosis lesionsAntimycobacterial therapyLesion diameterCutaneous sarcoidosisSarcoidosis lesionsDisease severityPlacebo-controlled studyPlacebo-treated groupCompletion of therapyT cell functionChronic granulomatous diseaseT cell receptor stimulationSignificant reductionConcomitant levofloxacinPlacebo regimenRifampin regimenSingle-MaskedPlacebo groupTreat analysisDermatology centersTherapeutic optionsGranulomatous diseaseT cellsLesion severity
2005
Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors
Segman RH, Shefi N, Goltser-Dubner T, Friedman N, Kaminski N, Shalev AY. Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors. Molecular Psychiatry 2005, 10: 500-513. PMID: 15685253, DOI: 10.1038/sj.mp.4001636.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdolescentAdultFollow-Up StudiesGene Expression ProfilingGenetic MarkersHumansLeukocytes, MononuclearLife Change EventsMiddle AgedOligonucleotide Array Sequence AnalysisPredictive Value of TestsSeverity of Illness IndexStress Disorders, Post-TraumaticStress, PsychologicalSurvivorsConceptsGene expression signaturesPeripheral blood mononuclear cell gene expressionExpression signaturesTrauma survivorsPeripheral blood mononuclear cell gene expression profilesTime pointsDSM-IV diagnostic criteriaKey clinical featuresPost-traumatic stress disorder symptomsPost-traumatic stress disorderCell gene expression profilesClinical featuresOutcome predictorsEmergency roomPTSD symptom clustersDevelopment of PTSDPathogenetic implicationsDiagnostic criteriaChronic PTSDDiagnostic utilityEarly symptomsMental disordersNeuropsychiatric disordersSymptom clustersPTSD criteria