2009
Ligand Effects on Cross-linking Support a Conformational Mechanism for Serotonin Transport*
Tao Z, Zhang YW, Agyiri A, Rudnick G. Ligand Effects on Cross-linking Support a Conformational Mechanism for Serotonin Transport*. Journal Of Biological Chemistry 2009, 284: 33807-33814. PMID: 19837674, PMCID: PMC2797150, DOI: 10.1074/jbc.m109.071977.Peer-Reviewed Original ResearchConceptsN-terminal cyanogen bromide fragmentGamma-aminobutyric acid transporterCyanogen bromide fragmentsTransmembrane 1Cysteine residuesMutagenesis strategyAcid transportersConformational mechanismSerotonin transportCysteineCorresponding positionDisulfide CrossTransportersSynaptic cleftResiduesSame molecule
2002
Chemical Modification Strategies for Structure‐Function Studies
Rudnick G. Chemical Modification Strategies for Structure‐Function Studies. 2002, 125-141. DOI: 10.1002/0471434043.ch8.ChaptersTransmembrane domainConformational changesPolytopic membrane proteinsStructure-function studiesMembrane proteinsTransporter proteinsReactive residuesLipid bilayersProteinTransportersExternal faceExternal loopChemical modification strategiesDomainChemical modificationSubstrateCysteineResiduesSitesMembraneModificationBilayers