1995
Biogenic amine flux mediated by cloned transporters stably expressed in cultured cell lines: amphetamine specificity for inhibition and efflux.
Wall S, Gu H, Rudnick G. Biogenic amine flux mediated by cloned transporters stably expressed in cultured cell lines: amphetamine specificity for inhibition and efflux. Molecular Pharmacology 1995, 47: 544-50. PMID: 7700252.Peer-Reviewed Original ResearchMeSH Keywords1-Methyl-4-phenylpyridiniumAmphetaminesBiogenic MonoaminesBiological TransportCarrier ProteinsCell MembraneCells, CulturedCloning, MolecularCocaineDNA, ComplementaryDopamineDopamine Plasma Membrane Transport ProteinsHumansMazindolMembrane GlycoproteinsMembrane Transport ProteinsNerve Tissue ProteinsNeurotransmitter Uptake InhibitorsNorepinephrineNorepinephrine Plasma Membrane Transport ProteinsSerotoninSerotonin Plasma Membrane Transport ProteinsStimulation, ChemicalSubstrate SpecificitySymportersTransfectionConceptsBiogenic amine transportersCell linesAmine transportersRat serotonin transporterCultured cell linesInhibitor of transportRat dopamine transporterHuman norepinephrine transporterPlasma membraneLLC-PK1 cellsSubstrate effluxSubstrate influxDopamine transporterNorepinephrine transporterAmphetamine derivativesTransportersSerotonin transporterEffluxDistinct patternsP-chloroamphetamineAmine substratesCellsInhibited transportCDNAInhibitors
1993
From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters
Rudnick G, Clark J. From synapse to vesicle: The reuptake and storage of biogenic amine neurotransmitters. Biochimica Et Biophysica Acta 1993, 1144: 249-263. PMID: 8104483, DOI: 10.1016/0005-2728(93)90109-s.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPresynaptic plasma membraneBiogenic amine neurotransmittersEndogenous regulatory mechanismsSynaptic transmitter levelsPlasma membraneIndividual proteinsRegulatory mechanismsTransport systemMolecular levelSynaptic vesiclesAmine neurotransmittersIon gradientsTransportersVesiclesCDNARapid progressProteinNeurotransmittersRegulationMechanismMembraneSynapseTransmitter levels