2012
Filamins in Mechanosensing and Signaling
Razinia Z, Mäkelä T, Ylänne J, Calderwood DA. Filamins in Mechanosensing and Signaling. Annual Review Of Biophysics 2012, 41: 227-246. PMID: 22404683, PMCID: PMC5508560, DOI: 10.1146/annurev-biophys-050511-102252.Peer-Reviewed Original ResearchConceptsPlasma membraneActin filamentsActin-binding proteinsExtracellular matrix connectionsCortical rigidityActin cytoskeletonCellular functionsCell cortexTranscription factorsTransmembrane receptorsAdhesion proteinsCell shapeFilaminIon channelsDiverse arrayFunctional evidenceEssential roleProteinMatrix connectionsPhysical forcesMembraneFilamentsCytoskeletalMechanosensingCytoskeleton
2007
Integrin Cytoskeletal Interactions
Lad Y, Harburger DS, Calderwood DA. Integrin Cytoskeletal Interactions. Methods In Enzymology 2007, 426: 69-84. PMID: 17697880, DOI: 10.1016/s0076-6879(07)26004-5.Peer-Reviewed Original ResearchConceptsIntegrin cytoplasmic tailsCytoplasmic tailProtein-protein interaction studiesIntegrin-binding proteinsIntegrin adhesion receptorsCell-substratum adhesionCytoskeletal interactionsPlasma membraneCytoskeletal proteinsBiochemical signalsAdhesion receptorsIntracellular ligandsTail interactionsCellular activitiesIntegrin-cytoskeletal interactionsMechanical forcesRecombinant modelProteinInteraction studiesTailAdhesionInteractionRegulationDynamic interactionMembrane
2003
Talin forges the links between integrins and actin
Calderwood DA, Ginsberg MH. Talin forges the links between integrins and actin. Nature Cell Biology 2003, 5: 694-696. PMID: 12894175, DOI: 10.1038/ncb0803-694.Peer-Reviewed Original Research