2000
Reversible Block of the Calcium Release Channel/Ryanodine Receptor by Protamine, a Heparin Antidote
Koulen P, Ehrlich B. Reversible Block of the Calcium Release Channel/Ryanodine Receptor by Protamine, a Heparin Antidote. Molecular Biology Of The Cell 2000, 11: 2213-2219. PMID: 10888663, PMCID: PMC14914, DOI: 10.1091/mbc.11.7.2213.Peer-Reviewed Original ResearchConceptsCalcium release channelRyanodine receptorChannel activityIntracellular calcium releaseRelease channelRyanodine receptor activityReceptor type 1Application of protamineMechanism of actionChannel/ryanodine receptorCalcium release channel/ryanodine receptorRelease channel/ryanodine receptorBulk calcium concentrationAddition of heparinRyanodine receptor type 1Single-channel activityReceptor activityCalcium releaseType 1Muscle cellsCalcium concentrationSkeletal muscleHeparin antidoteReversible blockProtamine sulfate
1998
Characterization of the ryanodine receptor/channel of invertebrate muscle
Quinn K, Castellani L, Ondrias K, Ehrlich B. Characterization of the ryanodine receptor/channel of invertebrate muscle. American Journal Of Physiology 1998, 274: r494-r502. PMID: 9486309, DOI: 10.1152/ajpregu.1998.274.2.r494.Peer-Reviewed Original ResearchConceptsInvertebrate musclesRyanodine receptor/channelVertebrate skeletal muscleDiverse organismsCalcium release channel/ryanodine receptorRelease channel/ryanodine receptorChannel/ryanodine receptorSingle-channel conductanceReceptor/channelElectron microscopic analysisRyanodine receptorSkeletal muscleRelease channelCytoplasmic Ca2Single-channel currentsSpecific ryanodine bindingChannel conductanceSarcoplasmic reticulumRyRsRuthenium redInvertebratesCa2MammalianRyanodine bindingOrganisms