2017
Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols
Fey D, Aksamitiene E, Kiyatkin A, Kholodenko BN. Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols. Methods In Molecular Biology 2017, 1636: 417-453. PMID: 28730495, DOI: 10.1007/978-1-4939-7154-1_27.Peer-Reviewed Original ResearchConceptsReceptor tyrosine kinasesReceptor tyrosine kinase signalingMultiple cellular processesTyrosine kinase signalingCellular processesProtein phosphorylationKinase signalingNetwork biologySystems biologyTyrosine kinaseCell survivalIntegration of experimentsPowerful approachIntegrative approachBiologyComputational protocolQuantitative datasetsKinasePhosphorylationSignalingIdentification of salientApoptosisDifferentiationGlucose metabolismRegulation
2009
Multistrip Western Blotting to Increase Quantitative Data Output
Kiyatkin A, Aksamitiene E. Multistrip Western Blotting to Increase Quantitative Data Output. Methods In Molecular Biology 2009, 536: 149-161. PMID: 19378054, PMCID: PMC2923389, DOI: 10.1007/978-1-59745-542-8_17.Peer-Reviewed Original ResearchConceptsCell signaling researchDiverse cellular processesWestern blottingHigh-throughput technologiesQuantitative data outputModification statesCellular processesProtein abundanceSystems biologyDifferent proteinsSingle membrane sheetMembrane sheetsPolyacrylamide gelsBlottingProteinElectrophoretic transferImmunoblotting procedureBiologyAbundance