2002
Biological significance of insulin-like growth factor binding proteins
Weinzimer S, Cohen P. Biological significance of insulin-like growth factor binding proteins. NeuroImmune Biology 2002, 2: 37-65. DOI: 10.1016/s1567-7443(02)80007-2.Peer-Reviewed Original ResearchInsulin-like growth factorGrowth factorFree insulin-like growth factorIGF/IGFBP axisCleavage of IGFBPsIGF-dependent actionsIGF-independent actionsPotent mitogenic agentsIGFBP axisIGFBP proteasesIGF receptorInflammatory diseasesIGFBPsGrowth disordersMitogenic agentsCellular proliferationCell growthSomatic growthHigh affinityPathophysiologyCancerProteinFactorsDiseaseBiological significance
1999
Cellular Actions of Insulin-Like Growth Factor Binding Proteins
Ferry R, Katz L, Grimberg A, Cohen P, Weinzimer S. Cellular Actions of Insulin-Like Growth Factor Binding Proteins. Hormone And Metabolic Research 1999, 31: 192-202. PMID: 10226802, PMCID: PMC4151550, DOI: 10.1055/s-2007-978719.Peer-Reviewed Original ResearchConceptsInsulin-like growth factorFree insulin-like growth factorInsulin-like growth factor binding proteinGrowth factorCleavage of IGFBPsIGF-dependent actionsGrowth factor binding proteinFactor binding proteinPotent mitogenic agentsIGFBP proteasesIGF axisIGF receptorIGFBPsCellular actionsMitogenic agentsModulate levelsCellular proliferationCell growthBinding proteinSomatic growthHigh affinityProteinReceptorsThe IGF Axis in the Male Reproductive System
Weinzimer S, Cohen P. The IGF Axis in the Male Reproductive System. Contemporary Endocrinology 1999, 407-423. DOI: 10.1007/978-1-59259-712-3_18.Peer-Reviewed Original ResearchBenign prostatic hypertrophyIGF systemIGF receptorInsulin-like growth factor (IGF) systemAbnormal prostate growthGrowth factor systemMale reproductive systemIGF axisProstate growthProstatic hypertrophyProstatic carcinomaCommon conditionUrinary systemAutocrine interactionsObstructive conditionsHealthy prostateImportant cellsPeptide hormonesReproductive systemFactor systemIGFHypertrophyMetabolic functionsCell growthCarcinoma