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It is an epidemic,” said Jennifer Sherr, MD, professor of pediatrics and medical director of the pediatric diabetes program at Yale University School of Medicine, New Haven, Connecticut. When asked to explain what makes it an epidemic — uncontrolled glycemic levels, more youngsters being diagnosed — she replied with “All of the above.”

“We’ve never seen weight loss at this level before,” says Ania Jastreboff, MD, PhD, the director of the Yale Obesity Research Center at the Yale School of Medicine, who has been involved in research on the drug.

In a recent study, researchers found that lowering parent stress can help protect young children from obesity. When parents practiced mindfulness and stress-management skills, their children showed healthier eating patterns and avoided the weight gain seen in families that only focused on diet and exercise. The study was led by Yale Child Study Center faculty members Rajita Sinha, PhD, and Wendy Silverman, PhD, with Professor of Medicine Ania Jastreboff, MD, PhD. Jastrebroff also serves as the medical director at Yale Stress Center.

In a new book, Yale endocrinologist Ania Jastreboff teams up with Oprah Winfrey to transform how we think about health, weight, and obesity.

Yale research helped redefine obesity as a chronic metabolic disease and advanced next-generation treatments.

Yale researchers helped develop the first insulin pump, pioneering continuous insulin delivery and modern automated diabetes care.

Oprah Winfrey sits down with TODAY’s Jenna Bush Hager and Sheinelle Jones to talk about her new book “Enough: Your Health, Your Weight, and What It’s Like to Be Free” about her weight loss, the lifestyle changes she experienced, why the journey gave her a new sense of freedom, and how she proved her dad wrong about obesity when she learned it is not the fault of people who suffer from it. Then, her co-author Dr. Ania M. Jastreboff, endocrinologist and associate professor at the Yale School of Medicine, joins the conversation to discuss how GLP-1s work.

In People's new cover story, Oprah Winfrey, who has cowritten a new book on obesity with Yale School of Medicine's Ania Jastreboff, MD, PhD,shares her past struggles — and what life is like now on weight loss drugs.

Oprah Winfrey calls her new book with Yale School of Medicine's Ania Jastreboff, MD, PhD, a "public service."