2015
Regional brain volumes, diffusivity, and metabolite changes after electroconvulsive therapy for severe depression
Jorgensen A, Magnusson P, Hanson L, Kirkegaard T, Benveniste H, Lee H, Svarer C, Mikkelsen J, Fink-Jensen A, Knudsen G, Paulson O, Bolwig T, Jorgensen M. Regional brain volumes, diffusivity, and metabolite changes after electroconvulsive therapy for severe depression. Acta Psychiatrica Scandinavica 2015, 133: 154-164. PMID: 26138003, DOI: 10.1111/acps.12462.Peer-Reviewed Original ResearchElectroconvulsive therapyDiffusion tensor imagingDorsolateral prefrontal cortexAntidepressant effectsSevere depressionMetabolite changesRegional brain volumesBrain metabolite concentrationsProton MR spectroscopyT MR scanAntidepressant actionClinical responseHippocampal plasticityHippocampal volumeAmygdala volumeMagnetic resonanceBrain volumeOrbitofrontal cortexPrefrontal cortexBrain structuresTensor imagingMR spectroscopyMR scansLack of correlationMetabolite concentrations
2001
Tracking Brain Volume Changes in C57BL/6J and ApoE-Deficient Mice in a Model of Neurodegeneration: A 5-Week Longitudinal Micro-MRI Study
McDaniel B, Sheng H, Warner D, Hedlund L, Benveniste H. Tracking Brain Volume Changes in C57BL/6J and ApoE-Deficient Mice in a Model of Neurodegeneration: A 5-Week Longitudinal Micro-MRI Study. NeuroImage 2001, 14: 1244-1255. PMID: 11707081, DOI: 10.1006/nimg.2001.0934.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApolipoproteins EAtrophyBrainBrain IschemiaBrain MappingCerebral VentriclesDisease Models, AnimalHippocampusImage EnhancementImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingMaleMiceMice, Inbred C57BLMice, Neurologic MutantsMicroscopyNeurodegenerative DiseasesProsencephalonConceptsApoE-deficient miceModels of neurodegenerationPostischemic dayBrain atrophyMouse modelNeurodegenerative diseasesDorsal hippocampal volumeBrain volume changesMin of ischemiaHigh signal intensity areaTransgenic mouse modelProgression of pathologyCorresponding time pointsSignal intensity areaMagnetic resonance imagingHigh-resolution MRIT1-weighted MR imagingC57 miceDorsal hippocampusHippocampal volumeClinical conditionsIschemiaMRI studiesPredetermined protocolCognitive decline