2002
Beta IV Spectrin in Normal and Cancer Breast Cells
De Camilli P. Beta IV Spectrin in Normal and Cancer Breast Cells. 2002 DOI: 10.21236/ada418127.Peer-Reviewed Original ResearchBeta IV spectrinBreast cancerLower motor neuron syndromeMotor neuron syndromeNervous system functionSignificant neurological defectsAutoimmune impairmentParaneoplastic conditionNeuronal antigensNovel autoantigenAutoimmune responseCancer immunotherapyCancer patientsPathogenetic mechanismsNeurological conditionsSuch antibodiesSide effectsCancer tissuesNeurological defectsMutant miceAxonal physiologyBreast cellsCancerCancer cellsDiagnostic tool
2001
Autoimmunity to βIV spectrin in paraneoplastic lower motor neuron syndrome
Berghs S, Ferracci F, Maksimova E, Gleason S, Leszczynski N, Butler M, De Camilli P, Solimena M. Autoimmunity to βIV spectrin in paraneoplastic lower motor neuron syndrome. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 6945-6950. PMID: 11391009, PMCID: PMC34458, DOI: 10.1073/pnas.121170798.Peer-Reviewed Original ResearchConceptsLower motor neuron syndromeMotor neuron syndromeParaneoplastic neurological disordersAxons of motoneuronsSevere neurological diseaseAxon initial segmentNodes of RanvierAutoimmune pathogenesisAutoimmune targetNeurological symptomsBreast cancerPartial improvementNeurological diseasesAffected neuronsNeurological disordersSyndromeAutoantibodiesCancer removalCancer cellsBetaIV spectrinAutoimmunityMajor targetSurface epitopesPathogenesisAxons