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The Swartz Center

The Swartz Foundation sponsors a Center that fosters collaborative research and inter- disciplinary training in Computational and Systems Neuroscience at Yale. This Center was founded and directed by Xiao-Jing Wang from 2006 – 2012 and is currently directed by Jess Cardin and Steve Zucker.

Recent years have seen great strides in our understanding of sensory processing and plasticity at the cellular and molecular levels. A major challenge today is to firmly establish general principles of neural network function in the context of detailed neural mechanisms of basic cognitive functions.

Theory, computational modeling, and systems neuroscience play a critical role in this enterprise, especially in studies of neural circuits, which we believe hold the key to understanding the chain of causal links from molecules to complex and flexible behaviors. Topics of active research in this Program include attention and working memory, decision making, reinforcement learning, timing, variability and synchrony of neural activity, quantitative models for neural development and function, and sensory processing in naturalistic environments.

Core Labs

The core faculty consists of several labs that share a common goal of using computational and theoretical tools to elucidate the cellular mechanisms and neural dynamics underlying brain functions. We welcome new members of the Yale community whose work involves computational or theoretical approaches to join us.

Principal Investigators

  • Co-director

    Professor of Neuroscience; Deputy Chair, Neuroscience

    Research Interests
    • Autistic Disorder
    • Cerebral Cortex
    • Electrophysiology
    • Epilepsy
    • Interneurons
    • Neurobiology
    • Neurosciences
    • Schizophrenia
  • Co-director

    David and Lucille Packard Professor of Computer Science and Professor of Biomedical Engineering

    Research Interests
    • Biomedical Engineering
    • Computers
    • Mathematical Computing
    • Mathematics
    • Neurophysiology
    • Neurosciences
    • Robotics
    • Biomedical Research
  • Professor of Molecular, Cellular and Developmental Biology and of Physics and of Neuroscience

    Research Interests
    • Behavior
    • Drosophila
    • Motion Perception
    • Neurobiology
    • Sensation
    • Visual Perception
    • Computational Biology
    • Optogenetics
  • Vice Provost for Research and William Ziegler III Professor of Neuroscience and Professor of Ophthalmology and Visual Science; Vice Provost for Research, Office of the Provost

    Research Interests
    • Brain
    • Cerebral Cortex
    • Child Development
    • Nervous System
    • Synaptic Transmission
    • Neuronal Plasticity
    • Neurosciences
    • Visual Cortex
  • Professor of Ophthalmology and Visual Science

    Research Interests
    • Adaptation, Physiological
    • Neurophysiology
    • Retinal Ganglion Cells
    • Synapses
    • Retinal Cone Photoreceptor Cells
    • Retinal Bipolar Cells
  • Associate Professor of Psychiatry and of Neuroscience

    Research Interests
    • Behavior, Animal
    • Cognition
    • Electrophysiology
    • Hippocampus
    • Learning
    • Neuronal Plasticity
    • Spatial Behavior
    • Spatial Memory
    • Psychiatry and Psychology
  • Professor of Neuroscience and Associate Professor of Biomedical Engineering and of Psychiatry; Member, Program in Cellular Neuroscience, Neurodegeneration and Repair (CNNR); Associate Director, MD-PhD Program

    Research Interests
    • Autistic Disorder
    • Behavior
    • Dendrites
    • Electrophysiology
    • Neurobiology
    • Microscopy, Fluorescence, Multiphoton
  • Eugene Higgins Professor of Molecular Biophysics and Biochemistry and Professor of Physics

    Research Interests
    • Biophysics
    • Cilia
    • Microtubules
    • Mitosis
    • Neurobiology
    • Physics
    • Developmental Biology
    • Molecular Motor Proteins
    • Nanotechnology
  • Assistant Professor of Psychiatry and of Neuroscience

    Research Interests
    • Autistic Disorder
    • Cerebral Cortex
    • Dendrites
    • Electrophysiology
    • Interneurons
    • Neurobiology
    • Neurosciences
    • Schizophrenia
    • Models, Statistical
    • Computational Biology
  • Assistant Professor in Neuroscience; Assistant Professor, Neuroscience

    Research Interests
    • Behavior
    • Drosophila melanogaster
    • Electrophysiology
    • Insecta
    • Neurons
    • Synapses
  • Assistant Professor; Assistant Professor, Neuroscience

    Research Interests
    • Behavior
    • Neurobiology
    • Neuronal Plasticity
    • Neurophysiology
    • Neurosciences
    • Visual Pathways
    • Visual Perception
    • Computational Biology
    • Optogenetics
  • Assistant Professor of Neuroscience and of Psychology

    Research Interests
    • Attention
    • Macular Degeneration
    • Neurobiology
    • Neurons
    • Neurosciences
    • Visual Cortex
    • Prefrontal Cortex
    • Social Cognition
  • Associate Professor of Psychiatry

    Research Interests
    • Behavior, Animal
    • Learning
    • Memory
    • Neurophysiology
    • Psychiatry
    • Schizophrenia
    • Prefrontal Cortex