Alpha and Gamma Isoforms of the Type I Phosphatidylinositol 4‐phosphate 5‐kinase Regulate Distinct Stages of the Ca2+ Response in Mast Cells
Vasudevan L, Jeromin A, Volpicelli‐Daley L, De Camilli P, Baird B, Holowka D. Alpha and Gamma Isoforms of the Type I Phosphatidylinositol 4‐phosphate 5‐kinase Regulate Distinct Stages of the Ca2+ Response in Mast Cells. The FASEB Journal 2008, 22: 804.1-804.1. DOI: 10.1096/fasebj.22.1_supplement.804.1.Peer-Reviewed Original ResearchMast cellsER storesMast cell responsesRBL-2H3 mast cellsType IInflammatory mediatorsKO miceBone marrowStore-operated Ca 2IgE receptorCell responsesAntigen crosslinkingExocytotic releaseIP 3 receptorsCa 2Hydrolysis of phosphatidylinositolAntigenReceptorsEndoplasmic reticulumCellular localizationGamma isoformsInfluxCells