2012
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling
Bohdanowicz M, Balkin D, De Camilli P, Grinstein S. Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling. The FASEB Journal 2012, 26: 1065.1-1065.1. DOI: 10.1096/fasebj.26.1_supplement.1065.1.Peer-Reviewed Original Research
2001
PIP Kinase Iγ Is the Major PI(4,5)P2 Synthesizing Enzyme at the Synapse
Wenk M, Pellegrini L, Klenchin V, Di Paolo G, Chang S, Daniell L, Arioka M, Martin T, De Camilli P. PIP Kinase Iγ Is the Major PI(4,5)P2 Synthesizing Enzyme at the Synapse. Neuron 2001, 32: 79-88. PMID: 11604140, DOI: 10.1016/s0896-6273(01)00456-1.Peer-Reviewed Original ResearchConceptsSynaptojanin 1Clathrin-coated intermediatesPolyphosphoinositide phosphatase synaptojanin-1Coat recruitmentActin functionClathrin coatPositive regulatorEndocytic zonesPIPKIgammaSynthesizing enzymesRecruitmentIgammaSynapseDephosphorylationEndocytosisMajor brainElevated levelsRegulatorProteinActinEnzymeMembrane
2000
A Functional Link between Dynamin and the Actin Cytoskeleton at Podosomes
Ochoa G, Slepnev V, Neff L, Ringstad N, Takei K, Daniell L, Kim W, Cao H, McNiven M, Baron R, De Camilli P. A Functional Link between Dynamin and the Actin Cytoskeleton at Podosomes. Journal Of Cell Biology 2000, 150: 377-390. PMID: 10908579, PMCID: PMC2180219, DOI: 10.1083/jcb.150.2.377.Peer-Reviewed Original ResearchConceptsDynamin 2Rous sarcoma virus resultsFunctional linkAttachment sitesDynamin familyActin cytoskeletonActin turnoverGFP-actinAdhesion structuresPlasma membranePodosomesAdhesion plaquesDynaminCell transformationNontransformed cellsTubular invaginationsFluorescence recoverySimilar turnoverActinSubstratumVirus resultsCellsTurnoverCytoskeletonDramatic changes