1997
Suppression of Task-Related Saccades by Electrical Stimulation in the Primate's Frontal Eye Field
Burman D, Bruce C. Suppression of Task-Related Saccades by Electrical Stimulation in the Primate's Frontal Eye Field. Journal Of Neurophysiology 1997, 77: 2252-2267. PMID: 9163356, DOI: 10.1152/jn.1997.77.5.2252.Peer-Reviewed Original ResearchConceptsFrontal eye fieldPrimate frontal eye fieldSaccadic eye movementsElectrical stimulationEye fieldFEF sitesFoveal receptive fieldsSuppression of saccadesLow-intensity stimulationEye movementsCentral fixation targetMemory-guided saccadesAppropriate saccadeCortex anteriorFEF projectionsContraversive saccadesAnterior bankIntracortical microstimulationStimulation trialsPremotor cortexEvidence of suppressionReflexive saccadesMacaque monkeysSubcortical regionsFrontal lobe damage
1994
Physiological correlate of fixation disengagement in the primate's frontal eye field
Dias E, Bruce C. Physiological correlate of fixation disengagement in the primate's frontal eye field. Journal Of Neurophysiology 1994, 72: 2532-2537. PMID: 7884478, DOI: 10.1152/jn.1994.72.5.2532.Peer-Reviewed Original ResearchConceptsFrontal eye fieldPresaccadic activityEye fieldPrimate frontal eye fieldMs. 3Short-latency saccadesGap taskDisengagement of fixationFixation disengagementVisuomovement cellsExpress saccadesFEF neuronsMean latencyFixation targetSaccade latencyRhesus monkeysSaccade taskSaccadic targetTrialsResponse fieldSaccadesSaccade targetCell fieldNeuronsFixation pointNeural responses related to smooth-pursuit eye movements and their correspondence with electrically elicited smooth eye movements in the primate frontal eye field
Gottlieb J, MacAvoy M, Bruce C. Neural responses related to smooth-pursuit eye movements and their correspondence with electrically elicited smooth eye movements in the primate frontal eye field. Journal Of Neurophysiology 1994, 72: 1634-1653. PMID: 7823092, DOI: 10.1152/jn.1994.72.4.1634.Peer-Reviewed Original ResearchConceptsSmooth eye movementsFrontal eye fieldPursuit neuronsEye movementsEye fieldPosterior bankPursuit directionPrimate frontal eye fieldMonkey frontal eye fieldSmooth pursuit eye movementsDirectional tuningBroad directional tuningSaccadic eye movementsSmooth pursuit trackingPursuit cellsMost neuronsIntracortical microstimulationPursuit velocityFEF neuronsFEF regionSmooth pursuitRhesus monkeysRegion involvementNeuron responsesNeurons
1993
Dorsolateral prefrontal lesions and oculomotor delayed-response performance: evidence for mnemonic "scotomas"
Funahashi S, Bruce C, Goldman-Rakic P. Dorsolateral prefrontal lesions and oculomotor delayed-response performance: evidence for mnemonic "scotomas". Journal Of Neuroscience 1993, 13: 1479-1497. PMID: 8463830, PMCID: PMC6576716, DOI: 10.1523/jneurosci.13-04-01479.1993.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCuesEye MovementsMacaca mulattaMemoryOculomotor MusclesPrefrontal CortexReaction TimeSaccadesSpace PerceptionConceptsMemory-guided eye movementsPrefrontal lesionsPrefrontal cortexEye movementsDelay periodDelayed-response deficitsDorsolateral prefrontal lesionsDelayed-response performancePeripheral visual cuesDelayed-response paradigmFrontal eye field regionVisual field locationsSaccadic reaction timesUnilateral lesionsSpatial memory functionIpsilateral cuesMonkey prefrontal cortexODR taskOpposite hemifieldSpatial cuesVisual cuesSimple sensoryMemory mechanismsMemory deficitsVisual targets
1990
Visuospatial coding in primate prefrontal neurons revealed by oculomotor paradigms
Funahashi S, Bruce C, Goldman-Rakic P. Visuospatial coding in primate prefrontal neurons revealed by oculomotor paradigms. Journal Of Neurophysiology 1990, 63: 814-831. PMID: 2341879, DOI: 10.1152/jn.1990.63.4.814.Peer-Reviewed Original ResearchConceptsODR taskVisual cuesPrefrontal cortexVisual responsesVisual probe taskLocation of cuesPrincipal sulcusVisual fieldDelay-period activitySame visual stimuliPrimate Prefrontal NeuronsDirectional visual responsesPassive visual responsesPS neuronsTask-related activityProbe taskSaccadic eye movementsVisuospatial codingCue locationSingle neuron activityVisual stimuliBehavioral enhancementOculomotor paradigmsPhasic visual responsesPrefrontal neurons
1989
Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex
Funahashi S, Bruce C, Goldman-Rakic P. Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex. Journal Of Neurophysiology 1989, 61: 331-349. PMID: 2918358, DOI: 10.1152/jn.1989.61.2.331.Peer-Reviewed Original ResearchConceptsDelay-period activityDorsolateral prefrontal cortexPS neuronsPrefrontal cortexPrincipal sulcusDirectional delay-period activityMonkey dorsolateral prefrontal cortexSpontaneous rateFrontal eye field regionOculomotor delayed-response taskSpatial memory functionPeriod activityCue directionSaccadic eye movementsOculomotor behaviorPrimate prefrontal cortexSubsequent delay periodTask-related activityVisual field locationsExcitatory responsesMost neuronsAnterior bankArcuate sulcusInhibitory responsesFixation target
1987
The role of striate cortex in the guidance of eye movements in the monkey
Segraves M, Goldberg M, Deng S, Bruce C, Ungerleider L, Mishkin M. The role of striate cortex in the guidance of eye movements in the monkey. Journal Of Neuroscience 1987, 7: 3040-3058. PMID: 3668615, PMCID: PMC6569180, DOI: 10.1523/jneurosci.07-10-03040.1987.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEye MovementsMacacaMacaca mulattaPsychomotor PerformanceReaction TimeSaccadesVisual CortexConceptsInitiation of saccadesCentral fixation pointLatency of saccadesSaccadic eye movementsStriate cortexSmooth pursuitEye velocityEye movementsImpaired fieldSmooth pursuit eye velocityFixation pointStep-ramp stimuliPursuit eye velocityIntact visual systemCortical ablationOculomotor abnormalitiesStimulus velocityFoveal targetAccurate saccadesStationary stimuliCortexSaccadesMonkeysVisual hemifieldLong latency
1975
Quantitative analysis of unit response patterns in cat visual cortex
Pfingst B, Bruce C, Shinkman P. Quantitative analysis of unit response patterns in cat visual cortex. Experimental Neurology 1975, 46: 215-228. PMID: 1109339, DOI: 10.1016/0014-4886(75)90044-8.Peer-Reviewed Original ResearchConceptsCat visual cortexArea 18Visual cortexLong-latency componentsResponse patternsPeristimulus time histogramsContralateral eyeArea 17Cortical areasInhibitory periodExtracellular recordingsFlash stimuliTime histogramsResponse latency increasesLatency increaseExcitatoryCortexInhibitory activityTrial varianceSame vertical columnCellsDurationResponsePeriodNearby cells