2016
Reproducibility measurement of glutathione, GABA, and glutamate: Towards in vivo neurochemical profiling of multiple sclerosis with MR spectroscopy at 7T
Prinsen H, de Graaf RA, Mason GF, Pelletier D, Juchem C. Reproducibility measurement of glutathione, GABA, and glutamate: Towards in vivo neurochemical profiling of multiple sclerosis with MR spectroscopy at 7T. Journal Of Magnetic Resonance Imaging 2016, 45: 187-198. PMID: 27351712, PMCID: PMC5167659, DOI: 10.1002/jmri.25356.Peer-Reviewed Original Research
2009
Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy
Boumezbeur F, Mason GF, de Graaf RA, Behar KL, Cline GW, Shulman GI, Rothman DL, Petersen KF. Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy. Cerebrovascular And Brain Metabolism Reviews 2009, 30: 211-221. PMID: 19794401, PMCID: PMC2949111, DOI: 10.1038/jcbfm.2009.197.Peer-Reviewed Original ResearchConceptsNeuronal mitochondrial metabolismHealthy agingBrain mitochondrial metabolismElderly subjectsYoung subjectsBrain functionBrain mitochondrial functionGlutamate-glutamine cyclingMitochondrial metabolismVivo magnetic resonance spectroscopyAge-related changesChronic reductionLabeling of glutamineGlutamate concentrationYoung volunteersBiologic basisMagnetic resonance spectroscopyMitochondrial functionMetabolismSubjectsIndividual subjectsResonance spectroscopyTricarboxylic acid cycleCycle fluxAging
2000
Dependence of Oxygen Delivery on Blood Flow in Rat Brain: A 7 Tesla Nuclear Magnetic Resonance Study
Hyder F, Kennan R, Kida I, Mason G, Behar K, Rothman D. Dependence of Oxygen Delivery on Blood Flow in Rat Brain: A 7 Tesla Nuclear Magnetic Resonance Study. Cerebrovascular And Brain Metabolism Reviews 2000, 20: 485-498. PMID: 10724113, DOI: 10.1097/00004647-200003000-00007.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingCapillary bedOxygen deliveryML xCerebral oxygen deliveryNicotine hydrogen tartrateRespective control conditionsValues of CBFMorphine anesthesiaSensorimotor cortexForepaw stimulationSodium pentobarbitalRat brainBlood flowCMRO2Mature ratsCortical activityResonance imagingBasal conditionsPercentage changeRatsAdministrationCBF
1998
A novel k‐space trajectory measurement technique
Zhang Y, Hetherington H, Stokely E, Mason G, Twieg D. A novel k‐space trajectory measurement technique. Magnetic Resonance In Medicine 1998, 39: 999-1004. PMID: 9621924, DOI: 10.1002/mrm.1910390618.Peer-Reviewed Original ResearchEvaluation of 31P metabolite differences in human cerebral gray and white matter
Mason G, Chu W, Vaughan J, Ponder S, Twieg D, Adams D, Hetherington H. Evaluation of 31P metabolite differences in human cerebral gray and white matter. Magnetic Resonance In Medicine 1998, 39: 346-353. PMID: 9498589, DOI: 10.1002/mrm.1910390303.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAdultAlgorithmsBrainBrain DiseasesEnergy MetabolismEvaluation Studies as TopicFemaleFourier AnalysisHumansHydrogen-Ion ConcentrationImage Processing, Computer-AssistedMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMalePhosphatesPhosphocreatinePhosphorusPhosphorus IsotopesRegression Analysis
1997
Biological and clinical MRS at ultra‐high field
Hetherington H, Pan J, Chu W, Mason G, Newcomer B. Biological and clinical MRS at ultra‐high field. NMR In Biomedicine 1997, 10: 360-371. PMID: 9542734, DOI: 10.1002/(sici)1099-1492(199712)10:8<360::aid-nbm477>3.0.co;2-8.Peer-Reviewed Original ResearchMeSH KeywordsBrainElectromagnetic FieldsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMagnetic Resonance SpectroscopySignal Processing, Computer-AssistedA Method to measure arbitrary k‐space trajectories for rapid MR imaging
Mason G, Harshbarger T, Hetherington H, Zhang Y, Pohost G, Twieg D. A Method to measure arbitrary k‐space trajectories for rapid MR imaging. Magnetic Resonance In Medicine 1997, 38: 492-496. PMID: 9339451, DOI: 10.1002/mrm.1910380318.Peer-Reviewed Original ResearchArtifactsBrainHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingReproducibility of ResultsA General Approach to Error Estimation and Optimized Experiment Design, Applied to Multislice Imaging ofT1in Human Brain at 4.1 T
Mason G, Chu W, Hetherington H. A General Approach to Error Estimation and Optimized Experiment Design, Applied to Multislice Imaging ofT1in Human Brain at 4.1 T. Journal Of Magnetic Resonance 1997, 126: 18-29. PMID: 9177795, DOI: 10.1006/jmre.1997.1143.Peer-Reviewed Original Research
1996
Quantitative 1H spectroscopic imaging of human brain at 4.1 T using image segmentation
Hetherington H, Pan J, Mason G, Adams D, Vaughn M, Twieg D, Pohost G. Quantitative 1H spectroscopic imaging of human brain at 4.1 T using image segmentation. Magnetic Resonance In Medicine 1996, 36: 21-29. PMID: 8795016, DOI: 10.1002/mrm.1910360106.Peer-Reviewed Original Research
1995
Proton nuclear magnetic resonance spectroscopic imaging of human temporal lobe epilepsy at 4.1 T
Hetherington H, Kuzniecky R, Pan J, Mason G, Morawetz R, Harris C, Faught E, Vaughan T, Pohost G. Proton nuclear magnetic resonance spectroscopic imaging of human temporal lobe epilepsy at 4.1 T. Annals Of Neurology 1995, 38: 396-404. PMID: 7668825, DOI: 10.1002/ana.410380309.Peer-Reviewed Original ResearchMeSH KeywordsAdultAspartic AcidCholineCreatineElectroencephalographyEpilepsy, Temporal LobeFemaleHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleProtonsConceptsTemporal lobe epilepsyMagnetic resonance spectroscopic imagingProton magnetic resonance spectroscopic imagingLobe epilepsyAcetylaspartate ratioMetabolic abnormalitiesEpileptic focusBilateral independent seizure onsetHuman temporal lobe epilepsyIntractable temporal lobe epilepsyIntracranial electroencephalographic studiesOperated temporal lobeNormal control subjectsDistinctive metabolic profileMagnetic resonance imagingContralateral abnormalitiesControl subjectsSeizure onsetCholine levelsHealthy volunteersN-acetylaspartateTemporal lobePatientsEpilepsyResonance imaging
1994
Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1T
Hetherington H, Mason G, Pan J, Ponder S, Vaughan J, Twieg D, Pohost G. Evaluation of cerebral gray and white matter metabolite differences by spectroscopic imaging at 4.1T. Magnetic Resonance In Medicine 1994, 32: 565-571. PMID: 7808257, DOI: 10.1002/mrm.1910320504.Peer-Reviewed Original Research2D 1H spectroscopic imaging of the human brain at 4.1 T
Hetherington H, Pan J, Mason G, Ponder S, Twieg D, Deutsch G, Mountz J, Pohost G. 2D 1H spectroscopic imaging of the human brain at 4.1 T. Magnetic Resonance In Medicine 1994, 32: 530-534. PMID: 7997121, DOI: 10.1002/mrm.1910320417.Peer-Reviewed Original ResearchDetection of brain glutamate and glutamine in spectroscopic images at 4.1 T
Mason G, Pan J, Ponder S, Twieg D, Pohost G, Hetherington H. Detection of brain glutamate and glutamine in spectroscopic images at 4.1 T. Magnetic Resonance In Medicine 1994, 32: 142-145. PMID: 7916115, DOI: 10.1002/mrm.1910320121.Peer-Reviewed Original Research