Elizabeth Woo
MD, PhD Student, NeuroscienceAbout
Research
Publications
2025
Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness
Yang S, Datta D, Krienen F, Woo E, May A, Anderson G, Galvin V, Gonzalez-Burgos G, Lewis D, Ling E, McCarroll S, Arnsten A, Wang M. Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness. Molecular Psychiatry 2025, 31: 1190-1200. PMID: 41413200, PMCID: PMC12929064, DOI: 10.1038/s41380-025-03425-y.Peer-Reviewed Original ResearchAdvancements in Cellular Therapeutics in Corneal Diseases
Woo E, Henick D, Tahvildari M. Advancements in Cellular Therapeutics in Corneal Diseases. Cells 2025, 14: 1838. PMID: 41369327, PMCID: PMC12691177, DOI: 10.3390/cells14231838.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsRyanodine receptor 2-mediated calcium leak is associated with increased glyoxalase I in the aging brain
Woo E, Datta D, Bathla S, Beatty H, Caglayan P, Albizu A, Lam T, Kanyo J, Joyce M, Leslie S, Uchendu S, DeLong J, Guan Q, Li J, Abramson E, Herman A, Cooper D, Licznerski P, Horvath T, Jonas E, Nairn A, Arnsten A, Sansing L. Ryanodine receptor 2-mediated calcium leak is associated with increased glyoxalase I in the aging brain. JCI Insight 2025, 10: e184041. PMID: 41100182, PMCID: PMC12643534, DOI: 10.1172/jci.insight.184041.Peer-Reviewed Original ResearchDysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation
Bathla S, Datta D, Bolat D, Woo E, Duque A, Arellano J, Arnsten A, Nairn A. Dysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation. Frontiers In Aging Neuroscience 2025, 17: 1549770. PMID: 40365352, PMCID: PMC12069431, DOI: 10.3389/fnagi.2025.1549770.Peer-Reviewed Original Research
2024
Key Roles of CACNA1C/Cav1.2 and CALB1/Calbindin in Prefrontal Neurons Altered in Cognitive Disorders
Datta D, Yang S, Joyce M, Woo E, McCarroll S, Gonzalez-Burgos G, Perone I, Uchendu S, Ling E, Goldman M, Berretta S, Murray J, Morozov Y, Arellano J, Duque A, Rakic P, O’Dell R, van Dyck C, Lewis D, Wang M, Krienen F, Arnsten A. Key Roles of CACNA1C/Cav1.2 and CALB1/Calbindin in Prefrontal Neurons Altered in Cognitive Disorders. JAMA Psychiatry 2024, 81: 870-881. PMID: 38776078, PMCID: PMC11112502, DOI: 10.1001/jamapsychiatry.2024.1112.Peer-Reviewed Original Research
2022
Inhibition of glutamate-carboxypeptidase-II in dorsolateral prefrontal cortex: potential therapeutic target for neuroinflammatory cognitive disorders
Yang S, Datta D, Elizabeth Woo, Duque A, Morozov YM, Arellano J, Slusher BS, Wang M, Arnsten AFT. Inhibition of glutamate-carboxypeptidase-II in dorsolateral prefrontal cortex: potential therapeutic target for neuroinflammatory cognitive disorders. Molecular Psychiatry 2022, 27: 4252-4263. PMID: 35732693, PMCID: PMC9718677, DOI: 10.1038/s41380-022-01656-x.Peer-Reviewed Original ResearchGlutamate Metabotropic Receptor Type 3 (mGlu3) Localization in the Rat Prelimbic Medial Prefrontal Cortex
Woo E, Datta D, Arnsten AFT. Glutamate Metabotropic Receptor Type 3 (mGlu3) Localization in the Rat Prelimbic Medial Prefrontal Cortex. Frontiers In Neuroanatomy 2022, 16: 849937. PMID: 35444520, PMCID: PMC9013768, DOI: 10.3389/fnana.2022.849937.Peer-Reviewed Original ResearchUnusual Molecular Regulation of Dorsolateral Prefrontal Cortex Layer III Synapses Increases Vulnerability to Genetic and Environmental Insults in Schizophrenia
Arnsten AFT, Woo E, Yang S, Wang M, Datta D. Unusual Molecular Regulation of Dorsolateral Prefrontal Cortex Layer III Synapses Increases Vulnerability to Genetic and Environmental Insults in Schizophrenia. Biological Psychiatry 2022, 92: 480-490. PMID: 35305820, PMCID: PMC9372235, DOI: 10.1016/j.biopsych.2022.02.003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2021
Glutamate Carboxypeptidase II in Aging Rat Prefrontal Cortex Impairs Working Memory Performance
Datta D, Leslie SN, Woo E, Amancharla N, Elmansy A, Lepe M, Mecca AP, Slusher BS, Nairn AC, Arnsten AFT. Glutamate Carboxypeptidase II in Aging Rat Prefrontal Cortex Impairs Working Memory Performance. Frontiers In Aging Neuroscience 2021, 13: 760270. PMID: 34867287, PMCID: PMC8634091, DOI: 10.3389/fnagi.2021.760270.Peer-Reviewed Original ResearchDiscovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette JE, Bertozzi CR, Wilen CB, Satpathy AT. Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions. Cell 2021, 184: 2394-2411.e16. PMID: 33743211, PMCID: PMC7951565, DOI: 10.1016/j.cell.2021.03.012.Peer-Reviewed Original Research
News
News
- December 15, 2023
Yuen Directs Film Production for Novel Intervention Program
- April 11, 2023
#TraineeTuesday: Elizabeth Woo
- March 09, 2023
Anna Lynn and Elizabeth Woo are 3-Minute Thesis Divisional Winners