2013
Concurrent Bloodstream Infections in Infants with Necrotizing Enterocolitis
Bizzarro MJ, Ehrenkranz RA, Gallagher PG. Concurrent Bloodstream Infections in Infants with Necrotizing Enterocolitis. The Journal Of Pediatrics 2013, 164: 61-66. PMID: 24139563, DOI: 10.1016/j.jpeds.2013.09.020.Peer-Reviewed Original ResearchConceptsBloodstream infectionsPost-NECNegative bacilliLate-onset bloodstream infectionConcurrent bloodstream infectionHospital course dataMean gestational ageCases of NECDiagnosis of NECOnset of diseaseMicrobiologic etiologyUnderappreciated complicationMicrobiologic dataNecrotizing enterocolitisGestational ageRetrospective reviewSingle centerSurgical interventionBirth weightRisk factorsHigher oddsInfantsNECEnterocolitisInfection
2008
Matched Case-Control Analysis of Polymicrobial Bloodstream Infection In A Neonatal Intensive Care Unit
Bizzarro MJ, Dembry LM, Baltimore RS, Gallagher PG. Matched Case-Control Analysis of Polymicrobial Bloodstream Infection In A Neonatal Intensive Care Unit. Infection Control And Hospital Epidemiology 2008, 29: 914-920. PMID: 18808341, DOI: 10.1086/591323.Peer-Reviewed Original ResearchMeSH KeywordsBacteremiaCase-Control StudiesFemaleFungemiaFungiGram-Negative BacteriaGram-Negative Bacterial InfectionsGram-Positive BacteriaGram-Positive Bacterial InfectionsHumansIncidenceInfant, Low Birth WeightInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfant, Very Low Birth WeightIntensive Care Units, NeonatalMaleRisk FactorsConceptsPolymicrobial bloodstream infectionsMonomicrobial bloodstream infectionSevere underlying conditionsBloodstream infectionsOnset of infectionUnderlying conditionRisk factorsMultivariate analysisIndwelling central venous catheterIntensive care unit patientsNeonatal intensive care unitMatched Case-Control AnalysisIndependent risk factorNewborn intensive care unit (NICU) patientsCare unit patientsCentral venous cathetersIntensive care unitNeonatal bloodstream infectionsMost risk factorsCase-control studyCase-control analysisCoagulase-negative staphylococciHospital NICUUnit patientsVenous cathetersChanging Patterns in Neonatal Escherichia coli Sepsis and Ampicillin Resistance in the Era of Intrapartum Antibiotic Prophylaxis
Bizzarro MJ, Dembry LM, Baltimore RS, Gallagher PG. Changing Patterns in Neonatal Escherichia coli Sepsis and Ampicillin Resistance in the Era of Intrapartum Antibiotic Prophylaxis. Pediatrics 2008, 121: 689-696. PMID: 18381532, DOI: 10.1542/peds.2007-2171.Peer-Reviewed Original ResearchMeSH KeywordsAmpicillinAmpicillin ResistanceAntibiotic ProphylaxisBacteremiaEscherichia coliEscherichia coli InfectionsFemaleFollow-Up StudiesHumansIncidenceInfant, NewbornInfectious Disease Transmission, VerticalMaleMultivariate AnalysisOdds RatioPregnancyPregnancy Complications, InfectiousPrenatal CareProbabilityRetrospective StudiesRisk AssessmentSeverity of Illness IndexStatistics, NonparametricSurvival RateConceptsE. coli early-onset sepsisEarly-onset sepsisLate-onset sepsisYale-New Haven HospitalIntrapartum antibiotic prophylaxisAntibiotic prophylaxisColi sepsisLow birth weight infantsAmpicillin resistanceAntibiotic prophylaxis practiceIntrapartum antibiotic exposureBirth weight infantsE. coli sepsisIndependent risk factorEscherichia coli sepsisAmpicillin exposureAmpicillin-resistant E. coliProphylaxis practicesSepsis rateWeight infantsNeonatal sepsisPreterm infantsTerm infantsRetrospective reviewRisk factors
2007
Case-control analysis of endemic Serratia marcescens bacteremia in a neonatal intensive care unit
Bizzarro MJ, Dembry LM, Baltimore RS, Gallagher PG. Case-control analysis of endemic Serratia marcescens bacteremia in a neonatal intensive care unit. Archives Of Disease In Childhood - Fetal And Neonatal Edition 2007, 92: f120. PMID: 17088342, PMCID: PMC2675455, DOI: 10.1136/adc.2006.102855.Peer-Reviewed Original ResearchMeSH KeywordsBacteremiaBirth WeightCase-Control StudiesConnecticutCross InfectionDrug Resistance, BacterialEndemic DiseasesEscherichia coliEscherichia coli InfectionsFemaleHumansInfant, NewbornIntensive Care Units, NeonatalMaleMicrobial Sensitivity TestsPrognosisRisk FactorsSerratia InfectionsSerratia marcescensConceptsNeonatal intensive care unitIntensive care unitCare unitUninfected controlsHospital Neonatal Intensive Care UnitSerratia marcescens bacteremiaMedian gestational ageCentral vascular catheterEscherichia coli bacteremiaRecords of infantsCase-control studyHigher overall mortalityE coliOnset of infectionCase-control analysisTime of infectionHigh rateAssociated meningitisHospital courseColi bacteremiaOverall mortalityGestational agePremature infantsVascular cathetersBirth weight
2005
Vancomycin-Resistant Enterococcal Bacteremia and Necrotizing Enterocolitis in a Preterm Neonate
Raskind CH, Dembry LM, Gallagher PG. Vancomycin-Resistant Enterococcal Bacteremia and Necrotizing Enterocolitis in a Preterm Neonate. The Pediatric Infectious Disease Journal 2005, 24: 943-944. PMID: 16220106, DOI: 10.1097/01.inf.0000180987.00122.5d.Peer-Reviewed Original ResearchSeventy-Five Years of Neonatal Sepsis at Yale: 1928–2003
Bizzarro MJ, Raskind C, Baltimore RS, Gallagher PG. Seventy-Five Years of Neonatal Sepsis at Yale: 1928–2003. Pediatrics 2005, 116: 595-602. PMID: 16140698, DOI: 10.1542/peds.2005-0552.Peer-Reviewed Original ResearchConceptsYale-New Haven HospitalEpisodes of sepsisLate-onset sepsisRecords of infantsPositive blood culturesNeonatal sepsisPreterm infantsBlood culturesSepsis-related mortality rateEarly-onset sepsisProlonged mechanical ventilationCentral vascular catheterNeonatal sepsis casesPopulation of infantsGroup B streptococciPercentage of casesDays of ageParenteral nutritionSepsis casesMechanical ventilationVascular cathetersIntensive careS pyogenesB streptococciSepsis
1999
Bacteremia, Meningitis, and Brain Abscesses in a Hospitalized Infant: Complications of Pseudomonas aeruginosa Conjunctivitis
Shah S, Gloor P, Gallagher P. Bacteremia, Meningitis, and Brain Abscesses in a Hospitalized Infant: Complications of Pseudomonas aeruginosa Conjunctivitis. Journal Of Perinatology 1999, 19: 462-465. PMID: 10685281, DOI: 10.1038/sj.jp.7200247.Peer-Reviewed Original ResearchConceptsSystemic complicationsBrain abscessesLow birth weight infantsNeonatal intensive care unitMultiple brain abscessesBirth weight infantsIntensive care unitWeight infantsPreterm infantsCorneal ulcerationNeonatal conjunctivitisCare unitSystemic diseasePoor visionCommon causeEye diseaseEye infectionsConjunctivitisMeningitisBacteremiaComplicationsInfantsAbscessP. aeruginosaPrompt detectionIncreasing incidence of Gram-negative rod bacteremia in a newborn intensive care unit
SHAH S, EHRENKRANZ R, GALLAGHER P. Increasing incidence of Gram-negative rod bacteremia in a newborn intensive care unit. The Pediatric Infectious Disease Journal 1999, 18: 591-595. PMID: 10440433, DOI: 10.1097/00006454-199907000-00005.Peer-Reviewed Original ResearchConceptsGNR bacteremiaCare unitNewborn Special Care UnitPercutaneous central venous cathetersNewborn intensive care unitYale-New Haven HospitalMaternal intrapartum antibioticsGram-negative rod bacteremiaDuration of hospitalizationCentral venous cathetersNegative rod bacteremiaIntensive care unitStepwise multivariate analysisSpecial care unitsNumber of admissionsIntrapartum antibioticsVenous cathetersRetrospective reviewOverall incidenceNeonatal careProspective studyPatient populationBacteremiaMultivariate analysisIncidence