2020
Characterization of circulating and cultured Tfh-like cells in sickle cell disease in relation to red blood cell alloimmunization status
Balbuena-Merle R, Santhanakrishnan M, Devine L, Gibb DR, Tormey CA, Siddon AJ, Curtis SA, Gallagher PG, Weinstein JS, Hendrickson JE. Characterization of circulating and cultured Tfh-like cells in sickle cell disease in relation to red blood cell alloimmunization status. Transfusion And Apheresis Science 2020, 59: 102778. PMID: 32439490, PMCID: PMC7483805, DOI: 10.1016/j.transci.2020.102778.Peer-Reviewed Original ResearchConceptsTfh-like cellsNaïve CD4 T cellsSickle cell diseaseCD4 T cellsCD4 T cell subsetsT cell subsetsT cellsCell diseaseRed blood cell alloimmunizationPeripheral blood mononuclear cellsBlood mononuclear cellsCD3/CD28Electronic medical recordsAlloimmunization statusHLA alloantibodiesRBC autoantibodiesRBC alloantibodiesFollicular helperIL-12Mononuclear cellsMedical recordsIL-7Antigen specificityB cellsAlloantibodies
2005
Expression of a KCC1 Splice Variant Is Suppressed by NF-ΚB in Erythroid Cells.
Anderson K, Crable S, Hammond S, Gallagher P, Joiner C. Expression of a KCC1 Splice Variant Is Suppressed by NF-ΚB in Erythroid Cells. Blood 2005, 106: 1669. DOI: 10.1182/blood.v106.11.1669.1669.Peer-Reviewed Original ResearchSickle cell diseaseSickle cell patientsNF-κBCell patientsPeripheral blood mononuclear cellsSS cellsInvolvement of TNFαBlood mononuclear cellsNF-κB expressionEffects of TNFαTranscription factor NF-κBAddition of TNFαTransferrin receptor antibodyRed cell hydrationFactor NF-κBK562 cellsRed cell volumeErythroid precursor cellsReceptor antibodiesMononuclear cellsCytokine presentCell diseaseStem cell factorVitro expressPotential modifier genes