2024
P-438 Association of uterine cavity immune cells at the time of frozen embryo transfer with live birth
Rodriguez S, Ibrahim M, Padula L, Fisher E, Rivas K, Paidas M, Strbo N, Attia G. P-438 Association of uterine cavity immune cells at the time of frozen embryo transfer with live birth. Human Reproduction 2024, 39: deae108.787. DOI: 10.1093/humrep/deae108.787.Peer-Reviewed Original ResearchTiming of frozen embryo transferFrozen embryo transferImprove pregnancy ratesT regulatory cellsLive birthsEmbryo transferImmune cellsPregnancy rateUterine segmentInfluence implantationUltrasound guidanceUterine milieuEndometrial receptivityElective single embryo transferFc receptor-positive cellsUpper uterusTotal immune cellsLower uterine segmentInstitutional review board approvalLive-born infantsSingle embryo transferImmune cell profilesLive birth rateGamma delta TCRImmune cell subsetsAssessment of immune cells in the uterine fluid at the time of the embryo transfer
Strbo N, Rodriguez S, Padula L, Fisher E, Lyons A, Rodriguez C, Rivas K, Ibrahim M, Paidas M, Attia G. Assessment of immune cells in the uterine fluid at the time of the embryo transfer. American Journal Of Reproductive Immunology 2024, 91: e13842. PMID: 38650366, DOI: 10.1111/aji.13842.Peer-Reviewed Original ResearchConceptsGamma delta T cellsFrozen embryo transferLower uterusAssisted reproductive technologyIn vitro fertilizationTransfer catheterT cellsEmbryo transferTime of implantationImmune milieuUpper uterusImmune cellsUltrasound guidanceExpression of CD4+ T cellsAssessment of immune cellsImprove IVF outcomesCD8+ T cellsCD4+ T cellsPopulation of T cellsComposition of immune cellsLower uterine segmentTime of embryo transferExpression of CD3+T regulatory cellsCD3+ cells
2023
P-489 Uterine fluid-immune cell analysis at the time of the embryo transfer
Strbo N, Rodriguez S, Ibrahim M, Padula L, Fisher E, Rivas K, Paidas M, Attia G. P-489 Uterine fluid-immune cell analysis at the time of the embryo transfer. Human Reproduction 2023, 38 DOI: 10.1093/humrep/dead093.832.Peer-Reviewed Original ResearchFrozen embryo transfer cyclesGamma delta T cellsLower uterusT cellsEmbryo transferTime of implantationImmune milieuImmune cellsUltrasound guidanceTransfer catheterUpper uterusProspective observational cohort studyDifferent immune cell subsetsFlow cytometryVitro Fertilization CyclesReproductive technology cyclesEmbryo transfer cyclesObservational cohort studyLower uterine segmentTRIAL REGISTRATION NUMBERFrozen embryo transferImmune cell subsetsNumber of CD45Delta T cellsExpression of CD4
2012
PreImplantation Factor (PIF) orchestrates systemic antiinflammatory response by immune cells: effect on peripheral blood mononuclear cells
Barnea ER, Kirk D, Ramu S, Rivnay B, Roussev R, Paidas MJ. PreImplantation Factor (PIF) orchestrates systemic antiinflammatory response by immune cells: effect on peripheral blood mononuclear cells. American Journal Of Obstetrics And Gynecology 2012, 207: 313.e1-313.e11. PMID: 23021695, DOI: 10.1016/j.ajog.2012.07.017.Peer-Reviewed Original ResearchConceptsPeripheral blood mononuclear cellsPreImplantation FactorSynthetic PIFBlood mononuclear cellsLymphocyte reactionMononuclear cellsImmune cellsSystemic effectsNaïve peripheral blood mononuclear cellsSynthetic preimplantation factorSystemic antiinflammatory effectMixed lymphocyte reactionImmune-modulatory propertiesTumor necrosis factorGranulocyte-macrophage colony-stimulating factorColony-stimulating factorSPIF effectNonpregnant patientsDiabetes mellitusMale patientsAntiinflammatory effectsIL-4Immune modulationSubset populationsAntiinflammatory response57: Preimplantation factor (PIF*) orchestrates systemic anti-inflammatory response by immune cells: a direct effect on peripheral blood mononuclear cells (PBMC)
Barnea E, Paidas M, Kirk D, Ramu S, Rivnay B, Sathiyaseelan T, Stamatkin C, Roussev R. 57: Preimplantation factor (PIF*) orchestrates systemic anti-inflammatory response by immune cells: a direct effect on peripheral blood mononuclear cells (PBMC). American Journal Of Obstetrics And Gynecology 2012, 206: s36-s37. DOI: 10.1016/j.ajog.2011.10.083.Peer-Reviewed Original Research