Hari Mcgrath
About
Biography
I work in the Yale Clinical Neuroscience Neuroanalytics lab as a graduate researcher. The focus of my work is on using brain atlases for multimodal data exploration and analysis in epilepsy surgery. I am also a final year medical student at King's College London. In the near future I hope to
Research
Publications
Featured Publications
High-resolution cortical parcellation based on conserved brain landmarks for localization of multimodal data to the nearest centimeter
McGrath H, Zaveri H, Collins E, Jafar T, Chishti O, Obaid S, Ksendzovsky A, Wu K, Papademetris X, Spencer D. High-resolution cortical parcellation based on conserved brain landmarks for localization of multimodal data to the nearest centimeter. Scientific Reports 2022, 12: 18778. PMID: 36335146, PMCID: PMC9637135, DOI: 10.1038/s41598-022-21543-3.Peer-Reviewed Original ResearchConceptsEpilepsy surgery cohortStandardized brain regionsBrain structure-function relationshipsSurgery cohortClinical usefulnessBrain metricsAnatomical locationBrain regionsBrain localizationCortical parcellationOwn unique benefitsIntracranial electroencephalographyAnatomical designationBrain anatomyHuman brain anatomyHuman brainBrain atlasBrain landmarksBrain atlasesParcellationMagnetic resonanceNearest centimeterAnatomical featuresAnatomyCortical localization
2024
Systematic 1 Hz direct electrical stimulation for seizure induction: A reliable method for localizing seizure onset zone and predicting seizure freedom
Sivaraju A, Quraishi I, Collins E, McGrath H, Ramos A, Turk-Browne N, Zaveri H, Damisah E, Spencer D, Hirsch L. Systematic 1 Hz direct electrical stimulation for seizure induction: A reliable method for localizing seizure onset zone and predicting seizure freedom. Brain Stimulation 2024, 17: 339-345. PMID: 38490472, DOI: 10.1016/j.brs.2024.03.011.Peer-Reviewed Original ResearchSeizure inductionSeizure onset zoneSurgical outcomesHabitual seizuresOnset zonePredicting seizure freedomExcellent surgical outcomesProspective cohort studyMann-Whitney testConsecutive patientsFisher's exactSeizure freedomRefractory epilepsyCohort studyPost-surgeryInsular regionsMann-WhitneyPatientsIntracranial EEGSeizuresLocalizing seizure onset zonesStimulationElectrical stimulationMedial temporal regionsTemporal regions
2023
Low-frequency monitoring for community clozapine initiations: A comparative study relative to standard frequency assessments
Mizuno Y, Bridglal D, Coumbe J, McGrath H, Adhikari A, Butler E, Bonoldi I, Taylor D, Howes O. Low-frequency monitoring for community clozapine initiations: A comparative study relative to standard frequency assessments. Journal Of Psychopharmacology 2023, 37: 627-629. PMID: 37171177, PMCID: PMC10291364, DOI: 10.1177/02698811231171532.Peer-Reviewed Original ResearchConceptsClozapine initiationChapter 7 The role of febrile seizures in directing surgical therapies for temporal lobe epilepsy
McGrath H, Lamsam L, Spencer D. Chapter 7 The role of febrile seizures in directing surgical therapies for temporal lobe epilepsy. 2023, 121-139. DOI: 10.1016/b978-0-323-89932-1.00010-x.ChaptersTemporal lobe epilepsyFebrile seizuresEpilepsy surgeryLobe epilepsyTreatment modalitiesMesial temporal sclerosisSurgical treatment optionsComprehensive preoperative evaluationSurgical treatment modalitiesTemporal sclerosisSurgical therapyPreoperative evaluationPreoperative findingsAppropriate therapyIntractable epilepsySurgical dataTreatment optionsClinical historyDisease processBetter outcomesSurgeryEpilepsySeizuresPatientsTherapy
2022
Optimizing the surgical management of MRI‐negative epilepsy in the neuromodulation era
McGrath H, Mandel M, Sandhu MRS, Lamsam L, Adenu‐Mensah N, Farooque P, Spencer DD, Damisah EC. Optimizing the surgical management of MRI‐negative epilepsy in the neuromodulation era. Epilepsia Open 2022, 7: 151-159. PMID: 35038792, PMCID: PMC8886105, DOI: 10.1002/epi4.12578.Peer-Reviewed Original ResearchConceptsDeep brain stimulationMRI-negative epilepsyInvasive monitoringResponsive neurostimulationBrain stimulationSeizure outcomeNerve stimulationMRI-negative focal epilepsyGood seizure outcomeLaser interstitial thermal therapyRetrospective chart reviewVagal nerve stimulationVagus nerve stimulationIntracranial electroencephalography monitoringClass 1Interstitial thermal therapyUnderwent resectionChart reviewMore patientsSurgical treatmentAppropriate therapySurgical managementPoor outcomeSurgical interventionSurgical outcomesArtificial intelligence and medical education: A global mixed-methods study of medical students’ perspectives
Ejaz H, McGrath H, Wong B, Guise A, Vercauteren T, Shapey J. Artificial intelligence and medical education: A global mixed-methods study of medical students’ perspectives. Digital Health 2022, 8: 20552076221089099. PMID: 35521511, PMCID: PMC9067043, DOI: 10.1177/20552076221089099.Peer-Reviewed Original ResearchMedical studentsMixed-methods studyMedical educationArtificial intelligenceComputer science studentsCore curriculumRobust teachingScience studentsTeachingStudentsMultidisciplinary educationCurriculumAlgorithm developmentEducationClinical medicineArtificial intelligence ethicsFocus groupsDigital futureKey stakeholdersIntelligence ethicsFoundational technologyIntelligenceKnowledgeSkillsPerspective
2021
Management of patients with medically intractable epilepsy and anterior temporal lobe encephaloceles.
Sandhu MRS, Mandel M, McGrath H, Lamsam L, Farooque P, Bronen RA, Spencer DD, Damisah EC. Management of patients with medically intractable epilepsy and anterior temporal lobe encephaloceles. Journal Of Neurosurgery 2021, 136: 709-716. PMID: 34507290, DOI: 10.3171/2021.3.jns21133.Peer-Reviewed Original ResearchConceptsTemporal lobe encephaloceleIdiopathic intracranial hypertensionRefractory epilepsyEEG findingsSigns of IIHIntractable temporal lobe epilepsyResective epilepsy surgeryManagement of patientsTemporal lobe epilepsyScalp EEG findingsSignificant neuropsychological deficitsRadiological findingsIntracranial hypertensionPreoperative evaluationEpileptogenic lesionsSurgical managementEpilepsy surgeryLobe epilepsySurgical outcomesIntractable epilepsySingle institutionSurgical dataEpileptogenic focusMedical recordsWorse outcomesBoost vaccine confidence with trust, not ire
McGrath H. Boost vaccine confidence with trust, not ire. Nature 2021, 595: 30-30. PMID: 34188214, DOI: 10.1038/d41586-021-01783-5.Commentaries, Editorials and LettersGerstmann Syndrome Deconstructed by Cortical Stimulation
Vaddiparti A, McGrath H, Benjamin C, Sivaraju A, Spencer DD, Hirsch LJ, Damisah E, Quraishi IH. Gerstmann Syndrome Deconstructed by Cortical Stimulation. Neurology 2021, 97: 420-422. PMID: 34187861, PMCID: PMC9246017, DOI: 10.1212/wnl.0000000000012441.Commentaries, Editorials and Letters
2020
Virtual Learning Innovations for Continuing Clinical Education during COVID-19
Hoernke K, McGrath H, Teh J, Salazar O. Virtual Learning Innovations for Continuing Clinical Education during COVID-19. Medical Science Educator 2020, 30: 1345-1346. PMID: 33020725, PMCID: PMC7527243, DOI: 10.1007/s40670-020-01090-0.Commentaries, Editorials and Letters