When lung cancer and breast cancer relapse, they often metastasize in the brain. The tumors that arise in the brain develop novel characteristics, differences that oft en confer resistance to existing drug therapies and create opportunities for new detection and treatment approaches for Yale Cancer Center researchers.
- April 15, 2020
A class of experimental cancer drugs called BET inhibitors have shown promise for treating cancers of the blood, but can induce toxic side effects. Now Yale researchers have found a new inhibitor that in animal studies demonstrates greater potency against a wider variety of cancers, as well as against solid tumors, and also produces fewer side effects compared to others in the class.
- January 30, 2020
Qin Yan, Ph.D., was presented with the Yale Cancer Center (YCC) Class of 1961 Cancer Research Award at YCC’s annual Conclave.
- January 16, 2020
Yale doctors have developed a way to create vascular grafts from stem cells that are as strong as the original blood vessels they would replace.
- May 09, 2017
New Haven’s biotech community has seen fits and starts, but today it is achieving critical mass. Upwards of 50 biotech and medical device companies employ more than 5,000 people in greater New Haven. Yale School of Medicine has been instrumental in the communty's growth.
- February 14, 2017Source: Office of Cooperative Research
Seventeen applications from Yale innovators have been named finalists for grants and resources from the Blavatnik Fund for Innovation at Yale, competing for up to $300,000 in Development grants or up to $100,000 in Pilot grants to accelerate their life science research into the marketplace. The $10 million fund supported by the Blavatnik Family Foundation launched this year to advance entrepreneurship in the life sciences at Yale and is managed by the Yale Office of Cooperative Research. Over 60 researchers applied for funding from across the Yale science disciplines, including chemistry, pharmacology, neuroscience, biomedical engineering, obstetrics, biophysics and immunobiology.
- February 09, 2017
A Yale-led research team identified how insulin-producing cells that are typically destroyed in type 1 diabetes can change in order to survive immune attack. The finding may lead to strategies for recovering these cells in diabetic patients, said the researchers.
- January 03, 2017
To better understand how cancer initiates and spreads, Yale associate professor of pathology Qin Yan turned to the field of epigenetics.
- July 27, 2016
A Yale research team has designed a system to modify, or edit, multiple genes in the genome simultaneously, while also minimizing unintended effects.
- July 19, 2016Source: Medical XPress
A team of investigators from Emory University School of Medicine and Winship Cancer Institute, Yale, and the National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health have obtained detailed structural information, showing how inhibitors of the KDM5 family interact with their targets.