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Nishant Kumar Mishra, MD, PhD, FRCP, FAHA

he/him/his
Assistant Professor of Neurology
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Additional Titles

Affiliated Faculty, Yale Institute of Global Health

Stroke Director, U.S. Department of Veterans Affairs, West Haven VA Medical Center

About

Titles

Assistant Professor of Neurology

Affiliated Faculty, Yale Institute of Global Health

Positions outside Yale

Stroke Director, U.S. Department of Veterans Affairs, West Haven VA Medical Center

Biography

Nishant K. Mishra, MD, PhD, FRCP, FESO, FAHA, is a stroke neurologist at Yale University School of Medicine's main hospital in New Haven and the Stroke Director at the West Haven Veteran Affairs Medical Center. He enjoys serving veterans and making a meaningful contribution to their lives. Dr. Mishra enrolled in Government Medical College/ Maharashtra University of Health Sciences in July 1999. He finished medical school in 2003 and his internship in January 2005.


Dr. Mishra's journey in stroke medicine started in 2005 at the Lilavati Hospital and Research Center, Bandra, Mumbai, where he found Praful M Dalal, MD, and Shirish M Hastak, MD, as his mentors, who introduced him to the art of clinical neurology, particularly vascular neurology. Dr. Dalal would tell him how he extracted tissue plasminogen activator from blood during his time at Oxford, studied the vascular anatomy by injecting dyes in the human brain, and how his approach was shaped working with his mentor Miller Fisher a long time ago. Young, enthusiastic, and focused, Dr. Mishra began looking for opportunities and went to Lausanne, known for the Lausanne Stroke Registry, in 2006. The Swiss Government fully funded this, and he learned clinical stroke and behavioral neurology under the mentorship of Antonio Carota, MD, Jean Marie Annoni, and many others.


Dr. Mishra was selected by Kennedy Lees, MD, at Glasgow, where he was fully funded to conduct his clinical research at the Western Infirmary Hospital, Glasgow. He was fully supported by the University of Glasgow and the Scottish Government's ORS funding. Through this, Dr. Mishra successfully defended a PhD thesis on using thrombolytic therapy beyond recommendations in acute ischemic stroke.


Subsequently, Dr. Greg Albers recruited him to Stanford, where he closely worked with experts like Maarten Lansberg, MD, PhD, and Soren Christensen, PhD, to develop expertise in perfusion image-based stroke outcome prognostication.


Subsequently, Dr. Mishra spent a year at the US Food and Drug Administration Center for Devices and Radiological Health, investigating sex differences in outcomes using TAVR devices.


Then, he spent five years doing a US ACGME residency (two years at Tulane, two years at Icahn School of Mount Sinai, and one year at UCLA) before moving to Yale.


Dr. Mishra has come to Yale and the West Haven VA Medical Center, Connecticut, with the following mission: (1) service through excellent clinical care; (2) build an extensive collaborative research program to promote stroke outcomes, e.g., IPSERC; (3) support the younger generation (trainees, junior faculties) in succeeding with their vision and making a meaningful contribution to society. IPSERC stands for International Post-Stroke Epilepsy Research Consortium, which Dr. Mishra founded together with Dr. Patrick Kwan, Professor of Epileptology at Monash University, Australia.

The research interests include post-stroke epilepsy, outcomes after cardiovascular procedures, women's health, thrombolysis, and prevention of complications from reperfusion therapy


See CURE Epilepsy talk on Post-Stroke Epilepsy Research Effort: https://cureepilepsy.org/webinars/webinar-epilepsy-and-neurodegenerative-disorders-the-relationship-between-stroke-and-seizures/ .


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Funded clinical research opportunities


Clinical research opportunities are funded through the VA/ Yale Advanced Postdoctoral Fellowship. Interested candidates can contact Dr. Mishra at nishant.mishra@va.gov.


We can host visiting trainees at Yale for collaborative projects.




Appointments

Other Departments & Organizations

Education & Training

Vascular Neurology ACGME Fellow
UCLA (2021)
NIH StrokeNet Fellow
UCLA (Mentors: J. Saver, MD; D.S. Liebeskind, MD) (2021)
MD
The University of The State of New York, By Conferral (2020)
Neurology Resident
Mt. Sinai Hospital, Icahn School of Medicine at Mt. Sinai (2020)
Neurology Resident
Tulane University (2018)
Internship
Tulane University (2017)
ORISE Medical Scientist
US Food and Drug Administration (2016)
Postdoctoral Fellow in Vascular Neurology
Stanford University (Mentors: G. Albers, MD; M. Lansberg, MD) (2014)
PhD
University of Glasgow, Medicine and Therapeutics (Mentor: K.R. Lees, MD, FRCP) (2012)
Visiting Researcher
UT Houston (Mentors: J. Grotta, MD; Collaborator: TA Kent, MD; P Mandava, MD) (2011)
Visiting ESO researcher
Karolinska University (Collaborator: N. Wahlgren, MD) (2009)
ESKAS Clinical Fellow
University of Lausanne, CHUV (Mentors: A. Carota, MD; J.M. Annoni, MD) (2008)
MBBS
Maharashtra University of Health Sciences, Nashik, India (2005)

Research

Overview

VA offers funded clinical research opportunities through the VA/ Yale Advanced Postdoctoral Fellowship. Interested candidates are welcome to contact Dr. Mishra at nishant.mishra@va.gov

Medical Research Interests

Biomarkers; Cerebrovascular Disorders; Clinical Protocols; Cognitive Reserve; Epilepsy; Global Health; Ischemic Stroke; Mechanical Thrombolysis; Neuroimaging; Neurology; Perfusion Imaging; Postoperative Cognitive Complications; Proteomics; Systematic Review

Public Health Interests

Clinical Guidelines; Clinical Trials; Global Health; History of Medicine and Science

Research at a Glance

Yale Co-Authors

Frequent collaborators of Nishant Kumar Mishra's published research.

Publications

Featured Publications

Clinical Trials

Current Trials

Academic Achievements & Community Involvement

  • activity

    PLOS One

  • activity

    World Stroke Organisation

  • activity

    European Stroke Organisation

  • activity

    Frontiers in Neurology (Stroke)

  • activity

    Stroke Journal

Clinical Care

Overview

Nishant Kumar Mishra, MBBS, PhD, MD, is a neurologist who specializes in vascular neurology and stroke. “My goal is to make a positive impact in the lives of stroke patients, not only by offering the best care, but also by advancing the field through clinical research and novel discoveries,” he says.

Dr. Mishra says he became a doctor because he wanted to be of service to people. “We deal with stroke on a daily basis, but our patients are dealing with it for the first time,” he says. Often stroke patients are figuring out how to manage cognitive issues, changes in mood, or questions about why this happened to them. “So, I try to offer them a good deal of time to get a sense of exactly what is going on with them, and then put myself in their shoes,” Dr. Mishra says. “If I wasn’t the doctor, how would I expect to be treated?”

Before he came to Yale in 2021, Dr. Mishra worked at several major stroke centers and neurology institutes around the world, and was a clinical scientist at the Food and Drug Administration. He made significant contributions to the field through his doctoral work, informing whether the exclusion criteria proposed by drug authorities for the treatment of ischemic stroke patients were meaningful and should be followed.

He also pursues clinical research that spans the breadth of stroke care, including acute intervention, prevention, and post-stroke recovery. “I’ve spent a large part of my life not only improving the outcomes of patients by optimizing their medical care, but also though research in collaborative efforts with my colleagues, and that has contributed to significant changes to the way we treat patients, which has really encouraged me to keep going,” he says.

Clinical Specialties

Neurology; Stroke

Get In Touch

Contacts

Locations

  • Department of Neurology

    Academic Office

    VA Connecticut Healthcare

    950 Campbell Avenue, Fl 6

    West Haven, CT 06516

  • 100 York Street

    Lab

    Wing Neurology, Ste 1-N, Rm 123

    New Haven, CT 06511

  • International Post-Stroke Epilepsy Research Consortium (IPSERC); Vascular Neurology Research Office

    Academic Office

    100 York Street, Ste Suite 1-N

    New Haven, CT 06511

    General Information

    785.785.5867
  • Patient Care Locations

    Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.