2024
Inducing representational change in the hippocampus through real-time neurofeedback
Peng K, Wammes J, Nguyen A, Iordan C, Norman K, Turk-Browne N. Inducing representational change in the hippocampus through real-time neurofeedback. Philosophical Transactions Of The Royal Society B Biological Sciences 2024, 379: 20230091. PMID: 39428880, PMCID: PMC11491844, DOI: 10.1098/rstb.2023.0091.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingReal-time functional magnetic resonance imagingPatterns of fMRI activityCategorical perception taskReal-time neurofeedbackNeurocognitive mechanismsFMRI sessionStimulus similarityFMRI activationTask demandsBehavioral consequencesUntrained objectsNeural representationPerception taskMemory integrationRepresentational changeEndogenous neuromodulatorNeurofeedbackHippocampusCortical representationIncreased coactivationMagnetic resonance imagingVisual cortexMemoryMultiple theoriesAcute Stress Effects on Statistical Learning and Episodic Memory
Sherman B, Huang I, Wijaya E, Turk-Browne N, Goldfarb E. Acute Stress Effects on Statistical Learning and Episodic Memory. Journal Of Cognitive Neuroscience 2024, 36: 1741-1759. PMID: 38713878, PMCID: PMC11223726, DOI: 10.1162/jocn_a_02178.Peer-Reviewed Original ResearchEpisodic memoryAcute stressStatistical learningEffects of acute stressStress-induced cortisol levelsImpaired episodic memoryModulate learning processesAcute stress effectsImpact hippocampal functionEpisodic encodingRodent workEvidence of learningHippocampal functionStress effectsHippocampal pathwaysLearning tasksBehavioral experimentsPreliminary evidenceCortisol levelsNo stressMemoryMultiple measuresHippocampusScene categoriesParticipants
2023
Automated and manual segmentation of the hippocampus in human infants
Fel J, Ellis C, Turk-Browne N. Automated and manual segmentation of the hippocampus in human infants. Developmental Cognitive Neuroscience 2023, 60: 101203. PMID: 36791555, PMCID: PMC9957787, DOI: 10.1016/j.dcn.2023.101203.Peer-Reviewed Original ResearchConceptsManual segmentationHippocampal segmentationInter-rater reliabilityAutomated SegmentationSegmentation methodSegmentationAnatomical MRI scansEarly hippocampal developmentHead motionFreeSurfer softwareSoftwareHippocampal developmentMRI scansHippocampal structureAwake infantsInfantsHippocampusFMRI protocolAnatomical scansGold standardAdult templateHuman infantsScan qualityScansProtocol
2022
Remembering the pattern: A longitudinal case study on statistical learning in spatial navigation and memory consolidation
Graves KN, Sherman BE, Huberdeau D, Damisah E, Quraishi IH, Turk-Browne NB. Remembering the pattern: A longitudinal case study on statistical learning in spatial navigation and memory consolidation. Neuropsychologia 2022, 174: 108341. PMID: 35961387, PMCID: PMC9578695, DOI: 10.1016/j.neuropsychologia.2022.108341.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexStatistical learningSpatial navigationBrain systemsDistinct brain systemsIntracranial electroencephalographyOffline consolidationPerceptual experienceCortical consolidationMemory consolidationPrefrontal cortexCortical regionsFuture behaviorLearningLongitudinal case studySame patientHippocampusConsolidationProlonged retentionRapid acquisitionWeeksElectroencephalographyCortexDifferent timescalesRegularityIncreasing stimulus similarity drives nonmonotonic representational change in hippocampus
Wammes J, Norman KA, Turk-Browne N. Increasing stimulus similarity drives nonmonotonic representational change in hippocampus. ELife 2022, 11: e68344. PMID: 34989336, PMCID: PMC8735866, DOI: 10.7554/elife.68344.Peer-Reviewed Original ResearchConceptsRepresentational changeHigh-level visual regionsShaped functionPairs of stimuliHigh-resolution fMRIStimulus similarityVisual regionsHuman participantsHippocampal learningMemoryPlasticity hypothesisCoactivationFMRIHippocampusGyrusStimuliWide enough rangeContradictory resultsParticipantsImage similarityLearningHypothesisU-shapeSimilar imagesEnough range
2021
Evidence of hippocampal learning in human infants
Ellis CT, Skalaban LJ, Yates TS, Bejjanki VR, Córdova NI, Turk-Browne NB. Evidence of hippocampal learning in human infants. Current Biology 2021, 31: 3358-3364.e4. PMID: 34022155, DOI: 10.1016/j.cub.2021.04.072.Peer-Reviewed Original ResearchConceptsStatistical learningHuman infantsTask-based fMRIMedial prefrontal cortexHuman memoryVisual sequencesDurable memoriesMemory capacityMemory integrationAnterior hippocampusHippocampal activityPrefrontal cortexVital abilityTemporal orderHippocampal learningEarly childhoodLearningMemoryMonosynaptic pathwayTrisynaptic pathwayHippocampusInfantsYounger agePosterior divisionFunctional activityLearning hierarchical sequence representations across human cortex and hippocampus
Henin S, Turk-Browne NB, Friedman D, Liu A, Dugan P, Flinker A, Doyle W, Devinsky O, Melloni L. Learning hierarchical sequence representations across human cortex and hippocampus. Science Advances 2021, 7: eabc4530. PMID: 33608265, PMCID: PMC7895424, DOI: 10.1126/sciadv.abc4530.Peer-Reviewed Original ResearchConceptsOrdinal positionTransitional probabilitiesBrain areasEarliest brain areasGradient of complexityVisual sequencesCortico-hippocampal circuitsNeural representationNeural trackingEarly processingBrain's abilityTemporal regularityStatistical learningAssociative regionsSensory inputLow-level featuresHuman cortexSequence representationParallel computational systemsMultiple levelsComputational systemsIntracranial electrodesCortexHippocampusProcessing
2020
Statistical prediction of the future impairs episodic encoding of the present
Sherman BE, Turk-Browne NB. Statistical prediction of the future impairs episodic encoding of the present. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 22760-22770. PMID: 32859755, PMCID: PMC7502714, DOI: 10.1073/pnas.2013291117.Peer-Reviewed Original ResearchConceptsFunction of memoryEpisodic encodingSource recallEpisodic memoryUpcoming itemsStatistical learningAdaptive purposeFuture experiencesMemoryCurrent itemPast experienceBrain imagingSpecific experiencesBehavioral testsIdiosyncratic propertiesItemsFuture situationsExperienceParticular momentHippocampusRecallEncodingSimilar situationLearningSituation
2019
The hippocampus as a visual area organized by space and time: A spatiotemporal similarity hypothesis
Turk-Browne NB. The hippocampus as a visual area organized by space and time: A spatiotemporal similarity hypothesis. Vision Research 2019, 165: 123-130. PMID: 31734633, PMCID: PMC6881556, DOI: 10.1016/j.visres.2019.10.007.Peer-Reviewed Original ResearchConceptsVision scienceMemory systemVisual systemVentral visual streamHippocampal memory systemRelational bindingEpisodic memoryVisual streamVisual expectationsHippocampal mechanismsPattern separationVisual areasStatistical learningSimilarity hypothesisVisual representationComputational functionsBrief primerHippocampusCertain aspectsMemoryHypothesisLearningUnique formCircuityScienceHippocampal-neocortical interactions sharpen over time for predictive actions
Hindy NC, Avery EW, Turk-Browne NB. Hippocampal-neocortical interactions sharpen over time for predictive actions. Nature Communications 2019, 10: 3989. PMID: 31488845, PMCID: PMC6728336, DOI: 10.1038/s41467-019-12016-9.Peer-Reviewed Original ResearchConceptsBackground connectivityAction-outcome associationsVisual cortexHigh-resolution fMRICo-occurring eventsHippocampal predictionsNeural patternsV1/V2Behavioral paradigmsAction informationPrediction changesIndiscriminate bindingGreater differentiationPredictive actionCortexHippocampusFMRIWeak associationReinstatementConnectivityAssociationParadigmOutcomesRetrievalAction
2017
Flexible weighting of diverse inputs makes hippocampal function malleable
Aly M, Turk-Browne NB. Flexible weighting of diverse inputs makes hippocampal function malleable. Neuroscience Letters 2017, 680: 13-22. PMID: 28587901, PMCID: PMC5712489, DOI: 10.1016/j.neulet.2017.05.063.Peer-Reviewed Original ResearchConceptsHippocampal functionAspects of cognitionDiverse cognitive functionsDedicated memory systemGeneral neural mechanismHippocampal computationsHippocampal representationsNeural mechanismsBehavioral goalsCognitive functionFlexible weightingMemory systemAnatomical inputsCognitionRecent researchPerceptionClassic theoryHippocampal modulationHippocampusDiverse inputsAttentionMemoryMalleabilityBroader roleRepresentationComplementary learning systems within the hippocampus: a neural network modelling approach to reconciling episodic memory with statistical learning
Schapiro AC, Turk-Browne NB, Botvinick MM, Norman KA. Complementary learning systems within the hippocampus: a neural network modelling approach to reconciling episodic memory with statistical learning. Philosophical Transactions Of The Royal Society B Biological Sciences 2017, 372: 20160049. PMID: 27872368, PMCID: PMC5124075, DOI: 10.1098/rstb.2016.0049.Peer-Reviewed Original ResearchConceptsStatistical learningRapid learningComplementary learning systems theoryComplementary learning systemsSequence of itemsEpisodic memoryIndividual episodesCognitive scienceAssociative reactivationTemporal regularityApparent representationIndividual experiencesNeural network modelling approachNeural network modelLearningLearning systemAnatomical pathwaysHippocampusSystems theoryHippocampal projectionsRegion CA1MemoryNetwork modelMemorizationExperience
2016
Linking pattern completion in the hippocampus to predictive coding in visual cortex
Hindy NC, Ng FY, Turk-Browne NB. Linking pattern completion in the hippocampus to predictive coding in visual cortex. Nature Neuroscience 2016, 19: 665-667. PMID: 27065363, PMCID: PMC4948994, DOI: 10.1038/nn.4284.Peer-Reviewed Original Research
2013
Mechanisms for Widespread Hippocampal Involvement in Cognition
Shohamy D, Turk-Browne NB. Mechanisms for Widespread Hippocampal Involvement in Cognition. Journal Of Experimental Psychology General 2013, 142: 1159-1170. PMID: 24246058, PMCID: PMC4065494, DOI: 10.1037/a0034461.Peer-Reviewed Original ResearchConceptsDeclarative memoryMedial temporal lobeCognitive psychologyMnemonic representationsCognitive processesBrain systemsHippocampal involvementModulation hypothesisMemory systemCognitionTemporal lobeMemoryHuman brainFunction hypothesisPervasive contributionTheoretical frameworkParallel researchHippocampusSpecial sectionPsychologyNeuroscienceSerendipitous encountersBrainDeclarativeHypothesis
2007
Interactions between attention and memory
Chun MM, Turk-Browne NB. Interactions between attention and memory. Current Opinion In Neurobiology 2007, 17: 177-184. PMID: 17379501, DOI: 10.1016/j.conb.2007.03.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMedial temporal lobe structuresRole of attentionDivision of attentionFrontal-parietal networkTemporal lobe structuresCognitive neuroscienceSpatial orientingAttention determineAttention taskConscious memoryUnconscious memoryConcurrent tasksSuch memoriesLobe structuresMemoryBrain areasStimuliTaskAttentionOrientingNeuroscienceLimited capacityRecent evidenceHippocampusInterdependence