2018
Bronchial hyper-responsiveness: a technical update
Borak J, Lefkowitz R, Linde B. Bronchial hyper-responsiveness: a technical update. Occupational Medicine 2018, 68: 519-522. PMID: 30192977, DOI: 10.1093/occmed/kqy122.Peer-Reviewed Original ResearchConceptsMethacholine challenge testingEuropean Respiratory SocietyAmerican Thoracic SocietyDiagnosis of asthmaNew guidelinesAsymptomatic asthmaticsBronchoprovocation testingPD20 valuesATS guidelinesDeep inspirationRespiratory SocietyThoracic SocietyTidal breathingChallenge testingHand searchSystematic reviewClinical testsLongitudinal assessmentBreath holdingAsthmaPD20CliniciansGuidelinesDelivery systemTechnical update
2017
Persistence of mercury-induced motor and sensory neurotoxicity: systematic review of workers previously exposed to mercury vapor
Fields CA, Borak J, Louis ED. Persistence of mercury-induced motor and sensory neurotoxicity: systematic review of workers previously exposed to mercury vapor. Critical Reviews In Toxicology 2017, 47: 849-870. PMID: 28722535, PMCID: PMC5962347, DOI: 10.1080/10408444.2017.1342599.Peer-Reviewed Original ResearchConceptsPhysical examinationElectrophysiological studiesSystematic reviewCessation of exposureHigh-dose exposurePrevious exposure studiesMercury workersSensory neurotoxicityNeurological findingsHistorical groupNeurobehavioral testsNeurotoxic effectsNB testingNeurotoxicityLimited available dataLongitudinal studyExposureFunctional significanceSensory effectsReviewHgCohortWorkersYearsStudyMercury-induced motor and sensory neurotoxicity: systematic review of workers currently exposed to mercury vapor
Fields CA, Borak J, Louis ED. Mercury-induced motor and sensory neurotoxicity: systematic review of workers currently exposed to mercury vapor. Critical Reviews In Toxicology 2017, 47: 815-848. PMID: 28718354, PMCID: PMC5931703, DOI: 10.1080/10408444.2017.1342598.Peer-Reviewed Original ResearchConceptsPhysical examinationMercury workersUrine mercury levelsStudy of neurotoxicityDental cohortNB outcomesSensory neurotoxicityAbnormal reflexesEligible studiesImpaired coordinationNeurobehavioral testsPE findingsNeurological effectsElectrophysiological studiesSystematic reviewNeurotoxicityNB testingManual dexterityNB testsTremorExposureOutcomesHistorical exposureMercury levelsTextbook chapters
2016
Chronic Beryllium Disease
Borak J. Chronic Beryllium Disease. Journal Of Occupational And Environmental Medicine 2016, 58: e355-e361. PMID: 27820771, DOI: 10.1097/jom.0000000000000869.Peer-Reviewed Original Research
2015
Bronchial hyperresponsiveness
Borak J, Lefkowitz RY. Bronchial hyperresponsiveness. Occupational Medicine 2015, 66: 95-105. PMID: 26590957, DOI: 10.1093/occmed/kqv158.Peer-Reviewed Original ResearchConceptsBronchial hyperresponsivenessBronchoprovocation testingChronic obstructive pulmonary disease patientsVariety of stimuliAssessment of BHRPrevalence of BHRObstructive pulmonary disease patientsPulmonary disease patientsDiagnosis of asthmaStudy of smokersGreat clinical valueBHR testingAirway diseaseLung diseaseDisease patientsClinical valueGeneral populationPathological mechanismsAsthmaHand searchSystematic reviewClinical patientsPatientsWorking populationHyperresponsiveness
2013
Is Diacetyl a Respiratory Sensitizer? A Reconsideration Using QSAR, QMM, and Competition Experiments
Dworak J, Roberts D, Calter M, Fields C, Borak J. Is Diacetyl a Respiratory Sensitizer? A Reconsideration Using QSAR, QMM, and Competition Experiments. Chemical Research In Toxicology 2013, 26: 631-633. PMID: 23593960, DOI: 10.1021/tx400097v.Peer-Reviewed Original Research
2012
Ecological Bias and Data Entry Errors
Borak J, Slade M, Allen R, Salipante-Zaidel C, Fields C. Ecological Bias and Data Entry Errors. Journal Of Occupational And Environmental Medicine 2012, 54: 770-773. DOI: 10.1097/jom.0b013e31825cb7c4.Peer-Reviewed Original ResearchMortality Disparities in Appalachia
Borak J, Salipante-Zaidel C, Slade MD, Fields CA. Mortality Disparities in Appalachia. Journal Of Occupational And Environmental Medicine 2012, 54: 146-156. PMID: 22258162, DOI: 10.1097/jom.0b013e318246f395.Peer-Reviewed Original Research
2011
Heavy Metals
Fields C, Borak J. Heavy Metals. Journal Of Occupational And Environmental Medicine 2011, 53: 587. DOI: 10.1097/jom.0b013e318216d0f5.Peer-Reviewed Original ResearchMethyl methacrylate and respiratory sensitization: A Critical review
Borak J, Fields C, Andrews LS, Pemberton MA. Methyl methacrylate and respiratory sensitization: A Critical review. Critical Reviews In Toxicology 2011, 41: 230-268. PMID: 21401327, PMCID: PMC3072694, DOI: 10.3109/10408444.2010.532768.Peer-Reviewed Original ResearchConceptsRespiratory sensitizersRespiratory sensitizationLocal lymph nodesUpper respiratory tractIrritation of eyesShort-term peak exposuresOccupational asthmaLymph nodesHypersensitivity pneumonitisCase reportRespiratory tractRespiratory effectsGuinea pigsNonspecific cytotoxicityRespiratory irritantsMedicine reportWorker studiesAsthmaSensitization testSkin sensitizationPeak exposuresDermal sensitizerVivo studiesToxicology literatureSensitization
2009
Hazardous Chemicals: Control and Regulation in the European Market
Lewis P, Borak J. Hazardous Chemicals: Control and Regulation in the European Market. Journal Of Occupational And Environmental Medicine 2009, 51: 112-113. DOI: 10.1097/jom.0b013e3181965dc9.Peer-Reviewed Original ResearchChapter 54 Iodine Deficiency in Vegetarian and Vegan Diets Evidence-Based Review of the World’s Literature on Iodine Content in Vegetarian Diets
Fields C, Borak J. Chapter 54 Iodine Deficiency in Vegetarian and Vegan Diets Evidence-Based Review of the World’s Literature on Iodine Content in Vegetarian Diets. 2009, 521-531. DOI: 10.1016/b978-0-12-374135-6.00054-6.Peer-Reviewed Original ResearchIodine deficiencyVegetarian dietRisk of iodineAdequate iodine intakeIodine contentEvidence-based reviewStrict vegetarian dietHigher socioeconomic statusPrenatal vitaminsIodine supplementsIodine intakeRestrictive dietsIodine nutritionLifestyle characteristicsPregnant vegetariansEpidemiological studiesIodized saltStrict vegetariansHealthful behaviorsDietary supplementsSuch dietsParticular riskSocioeconomic statusDietVegetarians
2008
Working Health: A Manual on Health Techniques for Aviators, Maintainers, and Aircraft Builders
DeHart R, Borak J. Working Health: A Manual on Health Techniques for Aviators, Maintainers, and Aircraft Builders. Journal Of Occupational And Environmental Medicine 2008, 50: 1084-1085. DOI: 10.1097/jom.0b013e31816fd6ae.Peer-Reviewed Original ResearchStatistical Evidence in Medical Trials: What Do the Data Really Tell Us?
Borak J. Statistical Evidence in Medical Trials: What Do the Data Really Tell Us? Journal Of Occupational And Environmental Medicine 2008, 50: 602. DOI: 10.1097/jom.0b013e3181650f20.Peer-Reviewed Original ResearchHow Everyday Products Make People Sick: Toxins at Home and in the Workplace
Borak J. How Everyday Products Make People Sick: Toxins at Home and in the Workplace. Journal Of Occupational And Environmental Medicine 2008, 50: 371-372. DOI: 10.1097/jom.0b013e318162f66e.Peer-Reviewed Original ResearchChapter 22: Toxicology of Complex Chemical Mixtures
Borak J, Fields C, Sirianni G, Luttrell W, Jederberg W, Still K. Chapter 22: Toxicology of Complex Chemical Mixtures. 2008, 275-282. DOI: 10.3320/978-1-931504-88-1.275.Peer-Reviewed Original Research
2007
Authors' Response
Borak J, Woolf S, Fields C. Authors' Response. Journal Of Occupational And Environmental Medicine 2007, 49: 358-359. DOI: 10.1097/jom.0b013e31803b9554.Peer-Reviewed Original Research
2006
Seafood arsenic: Implications for human risk assessment
Borak J, Hosgood HD. Seafood arsenic: Implications for human risk assessment. Regulatory Toxicology And Pharmacology 2006, 47: 204-212. PMID: 17092619, DOI: 10.1016/j.yrtph.2006.09.005.Peer-Reviewed Original ResearchConceptsComplex organic compoundsCarcinogenic mechanismsChronic arsenic exposureMargin of exposureOrganic compoundsDose-response curveArsenic speciesDietary seafoodHuman risk assessmentCarcinogenic dosesRodent studiesWorkplace exposuresArsenic exposureUS dietAdverse effectsInorganic formsFormation of metabolitesConservative dose estimatesCompoundsDose estimatesArsenical compoundsArsenicExposureSmall proportionRecent studiesAuthor's Response
Borak J. Author's Response. Journal Of Occupational And Environmental Medicine 2006, 48: 1000-1001. DOI: 10.1097/01.jom.0000237431.76206.6f.Peer-Reviewed Original ResearchUse of Beryllium Lymphocyte Proliferation Testing for Screening of Asymptomatic Individuals: An Evidence-Based Assessment
Borak J, Woolf SH, Fields CA. Use of Beryllium Lymphocyte Proliferation Testing for Screening of Asymptomatic Individuals: An Evidence-Based Assessment. Journal Of Occupational And Environmental Medicine 2006, 48: 937-947. PMID: 16966961, DOI: 10.1097/01.jom.0000232548.03207.9f.Peer-Reviewed Original ResearchConceptsAsymptomatic individualsLymphocyte proliferation testingProliferation testingBurden of sufferingChronic beryllium diseaseComputerized literature searchInsufficient scientific evidenceClinical benefitPreventive servicesEvidence-based assessmentRoutine screeningBeryllium diseaseBeryllium sensitizationEarly interventionHand searchLiterature searchBeLPTEarly detectionScientific evidenceMarked intraRelevant bibliographiesInterlaboratory variabilityIndividualsScreeningEvidence