2024
Comparison of organ involvement clusters in Black and White American sarcoidosis patients from a prospectively collected patient registry
Harper L, Tauquir A, Huang S, Wang X, Schupp J, Baughman R, Culver D. Comparison of organ involvement clusters in Black and White American sarcoidosis patients from a prospectively collected patient registry. Respiratory Medicine 2024, 226: 107605. PMID: 38537782, DOI: 10.1016/j.rmed.2024.107605.Peer-Reviewed Original Research
2023
Genetic and geographic influence on phenotypic variation in European sarcoidosis patients
Freitag-Wolf S, Schupp J, Frye B, Fischer A, Anwar R, Kieszko R, Mihailović-Vučinić V, Milanowski J, Jovanovic D, Zissel G, Bargagli E, Rottoli P, Bumbacea D, Jonkers R, Ho L, Gaede K, Dubaniewicz A, Marshall B, Günther A, Petrek M, Keane M, Haraldsdottir S, Bonella F, Grah C, Peroš-Golubičić T, Kadija Z, Pabst S, Grohé C, Strausz J, Safrankova M, Millar A, Homolka J, Wuyts W, Spencer L, Pfeifer M, Valeyre D, Poletti V, Wirtz H, Prasse A, Schreiber S, Dempfle A, Müller-Quernheim J. Genetic and geographic influence on phenotypic variation in European sarcoidosis patients. Frontiers In Medicine 2023, 10: 1218106. PMID: 37621457, PMCID: PMC10446882, DOI: 10.3389/fmed.2023.1218106.Peer-Reviewed Original ResearchAcute onsetOrgan involvementSarcoidosis phenotypesSingle nucleotide polymorphismsType of onsetCompetent ethics committeeGenetic variantsSarcoidosis cohortSarcoidosis patientsClinical featuresAcute diseaseVariable diseaseFull cohortClinical phenotypeHLA polymorphismObserved associationsEthics CommitteeOnset phenotypeStrong associationGenetic polymorphismsSignificant genetic associationSarcoidosisPatientsCohortAssociation
2021
FeV1 and BMI influence King’s Sarcoidosis Questionnaire score in sarcoidosis patients
Frye B, Potasso L, Farin-Glattacker E, Birring S, Müller-Quernheim J, Schupp J. FeV1 and BMI influence King’s Sarcoidosis Questionnaire score in sarcoidosis patients. BMC Pulmonary Medicine 2021, 21: 395. PMID: 34861850, PMCID: PMC8643005, DOI: 10.1186/s12890-021-01761-7.Peer-Reviewed Original ResearchConceptsKing's Sarcoidosis QuestionnaireBody mass indexSarcoidosis patientsQuality of lifeSerological parametersHigher body mass indexGerman Clinical Trials RegisterLife style modificationClinical Trials RegisterEffect of obesitySteroid-sparing therapiesLung functional parametersGeneral health statusOrgan-specific domainsConclusionThis observationKSQ scoresTrials RegisterClinical chartsMethodsClinical dataOrgan manifestationsLung functionMass indexClinical parametersStyle modificationTRIAL REGISTRATIONAbnormal FeV1 and body mass index are associated with impaired cough-related quality of life in sarcoidosis patients
Frye B, Potasso L, Farin E, Fichtner U, Birring S, Müller-Quernheim J, Schupp J. Abnormal FeV1 and body mass index are associated with impaired cough-related quality of life in sarcoidosis patients. Respiratory Medicine 2021, 188: 106600. PMID: 34530353, DOI: 10.1016/j.rmed.2021.106600.Peer-Reviewed Original ResearchConceptsLeicester Cough QuestionnaireCough-related qualityQuality of lifeSarcoidosis patientsLCQ scoreBody mass indexAbnormal FEV1Routine followLung functionOrgan impairmentTreatable traitsMass indexDisease burdenGranulomatous diseaseFEV1PatientsSarcoidosisBMIScoresQuestionnaireLungCohortFollowDiseaseLife
2019
Translation and psychometric properties of the King’s Sarcoidosis Questionnaire (KSQ) in German language
Farin E, Heyduck K, Frye BC, Birring SS, Müller-Quernheim J, Schupp JC. Translation and psychometric properties of the King’s Sarcoidosis Questionnaire (KSQ) in German language. Health And Quality Of Life Outcomes 2019, 17: 62. PMID: 30975148, PMCID: PMC6460543, DOI: 10.1186/s12955-019-1131-z.Peer-Reviewed Original ResearchConceptsKing's Sarcoidosis QuestionnaireGood psychometric propertiesGerman Clinical Trials RegisterGerman versionResultsOne hundred ninetyClinical Trials RegisterHealth-related qualityPsychometric propertiesGeneral health statusRasch model fitStructural validityInternal consistencyConstruct validityTrials RegisterConsecutive patientsSarcoidosis patientsOutpatient clinicInterventional studyLife QuestionnaireHealth statusSarcoidosisPatientsMeasurement propertiesCronbach's alphaStructured interviews
2018
Psychometric properties of the German version of the Leicester Cough Questionnaire in sarcoidosis
Schupp JC, Fichtner UA, Frye BC, Heyduck-Weides K, Birring SS, Windisch W, Criée CP, Müller-Quernheim J, Farin E. Psychometric properties of the German version of the Leicester Cough Questionnaire in sarcoidosis. PLOS ONE 2018, 13: e0205308. PMID: 30286204, PMCID: PMC6171952, DOI: 10.1371/journal.pone.0205308.Peer-Reviewed Original ResearchConceptsLeicester Cough QuestionnaireHRQL questionnairesSarcoidosis patientsHealth-related qualityPsychometric propertiesRasch model fitGerman versionInternal consistencyInterventional trialsCommon symptomsPulmonary medicineClinical settingSarcoidosisPatientsFloor effectsProfound negative impactModerate correlationConcurrent validitySkewed responseStructured interviewsQuestionnaireComparative questionnaireCoughCohortSymptoms