2022
L-ARGININE PREVENTS ISCHEMIC INJURY IN EXPLANTED RAT INTESTINAL REGIONS IN AN EX VIVO PERFUSION MODEL
Finotti M, Barahona M, Maina R, Lysyy T, Agarwal R, Schmitt P, Caturegli G, Di Renzo C, Anselmo A, Mulligan D, Geibel J, D'Amico F. L-ARGININE PREVENTS ISCHEMIC INJURY IN EXPLANTED RAT INTESTINAL REGIONS IN AN EX VIVO PERFUSION MODEL. Transplantation Reports 2022, 7: 100096. DOI: 10.1016/j.tpr.2022.100096.Peer-Reviewed Original ResearchIschemic injuryIntestinal segmentsIschemic damageIntraluminal perfusionNitric oxide-arginine pathwayMale Sprague-Dawley ratsN-nitroarginine methyl esterSprague-Dawley ratsEx vivo perfusion modelVivo perfusion modelNon-ischemic conditionsSmall intestinal segmentsFITC-inulinExtraluminal sideL-NAMEReperfusion injuryProtective effectL-arginineSmall intestinePerfusion modelInjuryIntestinal regionsFluid secretionReduced susceptibilityPerfusion
2017
Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury
Bertacco A, Dehner CA, Caturegli G, D'Amico F, Morotti R, Rodriguez MI, Mulligan DC, Kriegel MA, Geibel JP. Modulation of Intestinal Microbiome Prevents Intestinal Ischemic Injury. Frontiers In Physiology 2017, 8: 1064. PMID: 29311987, PMCID: PMC5742259, DOI: 10.3389/fphys.2017.01064.Peer-Reviewed Original ResearchIschemic injuryIntestinal ischemiaProtective effectIntestinal ischemic injuryLight-level microscopyEosin-stained sectionsLactate administrationAntibiotic treatmentIschemic protectionIntestinal barrierLactate perfusionRat modelIntestinal microbiomeIntestinal preservationIntestinal segmentsIschemic cellsSmall intestineInert sugarsInjuryIschemiaPerfusionEpithelium morphologySecretionPerfusion deviceFITC-inulin
2014
758 When Tissue Is the Issue: A New Device for Extracorporeal Hypothermic Perfusion of Intestinal Lumen and Vasculature Decreases the Rate of Necrosis During Graft Transportation
Narayan R, Patron-Lozano R, Loeb B, Oki K, Pancer N, Crouch A, Chauhan Y, Backus S, Fan R, Zinter J, Mulligan D, Emre S, Geibel J, Rodriguez-Davalos M. 758 When Tissue Is the Issue: A New Device for Extracorporeal Hypothermic Perfusion of Intestinal Lumen and Vasculature Decreases the Rate of Necrosis During Graft Transportation. Gastroenterology 2014, 146: s-1029-s-1030. DOI: 10.1016/s0016-5085(14)63753-7.Peer-Reviewed Original ResearchA Novel Device to Preserve Intestinal Tissue Ex-Vivo by Cold Peristaltic Perfusion
Narayan RR, Pancer NE, Loeb BW, Oki K, Crouch A, Backus S, Chauhan Y, Patrón-Lozano R, Rodriguez-Davalos MI, Geibel JP, Fan RE, Zinter JP. A Novel Device to Preserve Intestinal Tissue Ex-Vivo by Cold Peristaltic Perfusion. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2014, 2014: 3118-3121. PMID: 25570651, DOI: 10.1109/embc.2014.6944283.Peer-Reviewed Original Research
1994
Luminal perfusion of isolated gastric glands
Waisbren S, Geibel J, Boron W, Modlin I. Luminal perfusion of isolated gastric glands. American Journal Of Physiology 1994, 266: c1013-c1027. PMID: 8178950, DOI: 10.1152/ajpcell.1994.266.4.c1013.Peer-Reviewed Original Research