2009
Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy
Wang L, Sigworth FJ. Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy. Nature 2009, 461: 292-295. PMID: 19718020, PMCID: PMC2797367, DOI: 10.1038/nature08291.Peer-Reviewed Original ResearchConceptsVoltage sensor domainNative membrane environmentMembrane proteinsMembrane environmentChannel voltage-sensor domainElectron cryomicroscopyVoltage-activated potassium channelsSingle-particle electron cryomicroscopyIndividual protein particlesPotassium channelsBK potassium channelsLarge conductance calciumLipid membranesX-ray crystal structureBK channelsStructural studiesProtein particlesProteinCryomicroscopyCrystal structureFormation of crystalsDomainStructureCrystalsChannels
1989
Transmembrane Channels Based on Tartaric Acid-Gramicidin A Hybrids
Stankovic C, Heinemann S, Delfino J, Sigworth F, Schreiber S. Transmembrane Channels Based on Tartaric Acid-Gramicidin A Hybrids. Science 1989, 244: 813-817. PMID: 2471263, DOI: 10.1126/science.2471263.Peer-Reviewed Original Research