2020
1994-P: Task-Oriented Connectivity Analysis of Disease-Dependent Effects of Diet
WATT C, STANLEY T, LACADIE C, LAM K, SAVOYE M, SINHA R, CONSTABLE T, SEO D, HWANG J, BELFORT-DEAGUIAR R. 1994-P: Task-Oriented Connectivity Analysis of Disease-Dependent Effects of Diet. Diabetes 2020, 69 DOI: 10.2337/db20-1994-p.Peer-Reviewed Original ResearchMedial hippocampusFunctional MRIFunctional connectivityFood cue taskLow-calorie dietNational InstituteBrain functional connectivityLevel-dependent responsesModulation of emotionSignificant diet effectAnterior amygdalaInferior ponsObese subjectsKidney diseaseGlucose metabolismNeuronal controlMetabolic diseasesNeuronal adaptionBrain regionsBrain connectivityWeight lossDisease statesDiet effectsDietHippocampus
2011
Circulating glucose levels modulate neural control of desire for high-calorie foods in humans
Page KA, Seo D, Belfort-DeAguiar R, Lacadie C, Dzuira J, Naik S, Amarnath S, Constable RT, Sherwin RS, Sinha R. Circulating glucose levels modulate neural control of desire for high-calorie foods in humans. Journal Of Clinical Investigation 2011, 121: 4161-4169. PMID: 21926468, PMCID: PMC3195474, DOI: 10.1172/jci57873.Peer-Reviewed Original ResearchConceptsHigh-calorie foodsGlucose levelsHyperinsulinemic euglycemic-hypoglycemic clampsBrain regionsFunctional MRIMedial prefrontal cortexMedial prefrontal cortex activationRisk of overeatingLevels of glucosePostprandial reductionPrefrontal cortex activationObese subjectsNonobese individualsMild hypoglycemiaWorldwide epidemicCortex activationPrefrontal cortexFood cuesFood motivationFood stimuliNeural controlObesityInhibitory controlBehavioral measuresVisual cues
2009
Decreased Activity in Brain Regions of Emotion Regulation Predicted Alcohol Cravings during Stress and Alcohol-cue Exposures in Individuals with Alcohol Dependence
Seo D, Lacadie C, Bergquist K, Sinha R. Decreased Activity in Brain Regions of Emotion Regulation Predicted Alcohol Cravings during Stress and Alcohol-cue Exposures in Individuals with Alcohol Dependence. NeuroImage 2009, 47: s138. DOI: 10.1016/s1053-8119(09)71362-x.Peer-Reviewed Original Research