2024
Brain correlates and functional connectivity linking stress, autonomic dysregulation, and alcohol motivation
Seo D, Martins J, Sinha R. Brain correlates and functional connectivity linking stress, autonomic dysregulation, and alcohol motivation. Neurobiology Of Stress 2024, 31: 100645. PMID: 38933283, PMCID: PMC11201348, DOI: 10.1016/j.ynstr.2024.100645.Peer-Reviewed Original ResearchAutonomic nervous system disruptionAlcohol use disorderFunctional magnetic resonance imagingHigh-risk drinkingSocial drinkersFunctional connectivityLow-risk drinkingAlcohol motivationAutonomic arousalDevelopment of alcohol use disordersNeural correlates of stressNon-dependent social drinkersWhole-brain correlation analysesResponse to stress exposureAlcohol taste testFrontal-striatal regionsStress-induced cravingVentromedial prefrontal cortexBehaviors associated with stressAnterior cingulate cortexDecreased functional connectivityExposure to stressAutonomic nervous systemAlcohol intakeHazardous alcohol use
2015
Neuroplasticity and Predictors of Alcohol Recovery.
Seo D, Sinha R. Neuroplasticity and Predictors of Alcohol Recovery. Alcohol Research 2015, 37: 143-52. PMID: 26259094, PMCID: PMC4476600.Peer-Reviewed Original ResearchConceptsKey neural circuitsCognitive controlEmotion regulationNeurobiological literatureNeurobiological adaptationsAdrenal axis systemFuture research directionsNeuroplastic changesAlcohol recoveryNeural circuitsLimbic circuitsSignificant predictorsAutonomic nervous systemClinical implicationsNeuroplasticityRelevant clinical implicationsResearch directionsChronic alcoholismNervous systemChronic effectsPredictorsAlcoholismPhysiological responsesRecent evidenceNeuroadaptations