2024
Causal and common risk pathways linking childhood maltreatment to later intimate partner violence victimization
Pezzoli P, Pingault J, Eley T, McCrory E, Viding E. Causal and common risk pathways linking childhood maltreatment to later intimate partner violence victimization. Molecular Psychiatry 2024, 1-11. PMID: 39488656, DOI: 10.1038/s41380-024-02813-0.Peer-Reviewed Original ResearchIntimate partner violence victimizationIntimate partner violenceChildhood maltreatmentTwins Early Development StudyPartner violence victimizationSmall-to-moderate rangeNonshared environmental influencesEnvironmental influencesEarly Development StudyPsychiatric risk factorsEffects of maltreatmentRetrospective self-reportsRetrospective self-reports of maltreatmentIndividual-level riskPartner violenceViolence victimizationDevelopment studiesMaltreatmentVictimsIntimate relationshipsGenetic influencesCo-twinQuantitative genetic methodsRisk pathwaysModerating effectShedding Light on Antisocial Behavior Through Genetically Informed Research.
Pezzoli P, McCrory E, Viding E. Shedding Light on Antisocial Behavior Through Genetically Informed Research. Annual Review Of Psychology 2024 PMID: 39441883, DOI: 10.1146/annurev-psych-021524-043650.Peer-Reviewed Original ResearchIndividuals as active co-creators of their environments: implications for prevention of inequalities
Viding E, McCrory E. Individuals as active co-creators of their environments: implications for prevention of inequalities. Oxford Open Economics 2024, 3: i749-i753. DOI: 10.1093/ooec/odad071.Peer-Reviewed Original ResearchEarly adversityLatent vulnerabilityReduce inequalitiesGene-environment correlationAdaptability to adversityTargeted interventionsPattern of processingDispositional differencesPrevent inequalitiesEarly interventionContext of preventionInterventionIndividual dispositionsAdversityGenetic predispositionDevelopmental effectsCorrelational researchPreventionCo-creationActive co-creatorsIndividualsChildrenEducation domainInequalityLearning processSocial Learning and Preferences in Adolescents With Conduct Problems and Varying Levels of Callous-Unemotional Traits
Gaule A, Bevilacqua L, Molleman L, van den Bos W, van Duijvenvoorde A, Roberts R, Pease C, McCrory E, Viding E. Social Learning and Preferences in Adolescents With Conduct Problems and Varying Levels of Callous-Unemotional Traits. JAACAP Open 2024, 2: 79-89. DOI: 10.1016/j.jaacop.2023.12.008.Peer-Reviewed Original ResearchCallous-unemotional traitsConduct problemsTD adolescentsLevels of callous-unemotional traitsLevels of CU traitsDisplay aggressive behaviorCU traitsAdolescents' CPSocial learningSocial environmentNon-socialGroup differencesAggressive behaviorCP/LCUSocial behaviorObject learningDifficulty learningEconomic gamesSocial partnersSocial preferencesCP/HCUAdolescentsSocial relationshipsResults AdolescentsSocial worldReciprocal Effects Between Negative Parenting and Children’s Callous-Unemotional Traits From Mid to Late Childhood
Pezzoli P, Pingault J, Malanchini M, Voronin I, McCrory E, Fearon P, Viding E. Reciprocal Effects Between Negative Parenting and Children’s Callous-Unemotional Traits From Mid to Late Childhood. American Journal Of Psychiatry 2024, 181: 310-321. PMID: 38476045, DOI: 10.1176/appi.ajp.20230208.Peer-Reviewed Original ResearchChild CU traitsDevelopment of CU traitsCU traitsMid-to-late childhoodNegative parentingCallous-unemotionalTwins Early Development StudyLate childhoodLongitudinal cross-lagged modelsEffects of negative parentingCallous-unemotional traitsEarly Development StudyReciprocal effectsCross-lagged modelsCross-lagged effectsFamilies of childrenTwin pairsGenetic factorsParental disciplineParental feelingsChildhoodSmall effectsTraitsEnvironmental factorsParentsHeightened response to positive facial cues as a potential marker of resilience following childhood adversity
Gerin M, Viding E, Neil L, Armbruster-Genc D, Freeman Z, Sharp M, Phillips H, McCrory E. Heightened response to positive facial cues as a potential marker of resilience following childhood adversity. European Journal Of Psychotraumatology 2024, 15: 2309783. PMID: 38318813, PMCID: PMC10849006, DOI: 10.1080/20008066.2024.2309783.Peer-Reviewed Original ResearchConceptsFacial cuesMaltreatment experiencesPresence of social supportSocial supportLow symptomsAssociated with lower symptomsThreat-related cuesPositive social cuesIncreased psychiatric riskPerceived emotional intensityMarkers of resilienceChildhood maltreatment experiencesNo group differencesMental health symptomsLevels of social supportPerceived social supportAssociated with better mental healthMental health vulnerabilitiesMental health outcomesBetter mental healthExperiences of abusePerceived intensityHappy facesChildhood maltreatmentImplicit processesReduced prosocial motivation and effort in adolescents with conduct problems and callous‐unemotional traits
Gaule A, Martin P, Lockwood P, Cutler J, Apps M, Roberts R, Phillips H, Brown K, McCrory E, Viding E. Reduced prosocial motivation and effort in adolescents with conduct problems and callous‐unemotional traits. Journal Of Child Psychology And Psychiatry 2024, 65: 1061-1071. PMID: 38287126, DOI: 10.1111/jcpp.13945.Peer-Reviewed Original ResearchLevels of CU traitsCallous-unemotional traitsProsocial behaviorProsocial choicesConduct problemsProsocial actsCU traitsLevels of callous-unemotional traitsPsychopathy in adulthoodCognitive-affective mechanismsReduced prosocial behaviorLow prosocial behaviorBenefit othersTD peersAntisocial behaviorCP/HCUBehavioral levelBenefit oneselfCP/LCUReduced engagementProsocial motivationAdolescentsAdolescent boysTraitsReduced exertionAtypical Interpersonal Problem-Solving and Resting-state Functional Connectivity in Adolescents with Maltreatment Experience
Gerin M, Viding E, Puetz V, Armbruster-Genc D, Rankin G, McCrory E. Atypical Interpersonal Problem-Solving and Resting-state Functional Connectivity in Adolescents with Maltreatment Experience. Current Neuropharmacology 2024, 22: 290-301. PMID: 37818587, PMCID: PMC10788892, DOI: 10.2174/1570159x22666231002145440.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityPosterior cingulate cortexMedial prefrontal cortexMental health symptomsMaltreatment experiencesSocial functioningLingual gyrusFunctional connectivityHealth symptomsInterpersonal problem-solving skillsRetrosplenial cortexElevated mental health symptomsDefault mode network hubInterpersonal problem solvingPoor social functioningAdverse environmental experiencesProblem-solving performanceNon-maltreated peersProblem-solving skillsExperiences of abuseSeed-based analysisNeurocognitive processingNeurocognitive functioningMental health disordersEarly adversity
2023
A systematic review of childhood maltreatment and resting state functional connectivity
Gerin M, Viding E, Herringa R, Russell J, McCrory E. A systematic review of childhood maltreatment and resting state functional connectivity. Developmental Cognitive Neuroscience 2023, 64: 101322. PMID: 37952287, PMCID: PMC10665826, DOI: 10.1016/j.dcn.2023.101322.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityAnterior cingulate cortexFunctional connectivityCingulate cortexChildhood maltreatmentAltered functional connectivityState functional connectivityDorsal anterior cingulate cortexNegative psychiatric outcomesVentral anterior cingulate cortexDorsolateral prefrontal cortexRsFC alterationsAltered connectivityInclusion criteriaAmygdala connectivityNineteen studiesPsychiatric outcomesFuture symptomsSystematic reviewBrain regionsClinical disordersBrain circuitsAnterior insulaPrefrontal cortexMaltreatment exposureAn ‘embedded brain’ approach to understanding antisocial behaviour
Viding E, McCrory E, Baskin-Sommers A, De Brito S, Frick P. An ‘embedded brain’ approach to understanding antisocial behaviour. Trends In Cognitive Sciences 2023, 28: 159-171. PMID: 37718176, DOI: 10.1016/j.tics.2023.08.013.Peer-Reviewed Original Research
2022
A genetically informed Registered Report on adverse childhood experiences and mental health
Baldwin J, Sallis H, Schoeler T, Taylor M, Kwong A, Tielbeek J, Barkhuizen W, Warrier V, Howe L, Danese A, McCrory E, Rijsdijk F, Larsson H, Lundström S, Karlsson R, Lichtenstein P, Munafò M, Pingault J. A genetically informed Registered Report on adverse childhood experiences and mental health. Nature Human Behaviour 2022, 7: 269-290. PMID: 36482079, PMCID: PMC7614239, DOI: 10.1038/s41562-022-01482-9.Peer-Reviewed Original ResearchConceptsMental health problemsAdverse childhood experiencesHealth problemsElevated riskMental healthGenetic confoundingChildhood experiencesPsychiatric vulnerabilityGenetic riskHigher polygenic scoresConfoundingChildrenPrevious associationsRiskGene-environment correlationSmall increaseAssociationHealthReportPolygenic scoresParenting boys with conduct problems and callous-unemotional traits: parent and child perspectives
Roberts R, McCrory E, Joffe H, Phillips H, Gaule A, Viding E. Parenting boys with conduct problems and callous-unemotional traits: parent and child perspectives. European Child & Adolescent Psychiatry 2022, 32: 2547-2555. PMID: 36374342, PMCID: PMC10682176, DOI: 10.1007/s00787-022-02109-0.Peer-Reviewed Original ResearchConceptsCP/HCUCallous-unemotional traitsConduct problemsParents/caregiversTD boysInconsistent disciplineChildren’s perspectivesAlabama Parenting QuestionnaireParenting QuestionnaireChild monitoringMore difficultyLittle researchParentingQualitative reportsFamily engagementParentsSame perceptionCaregiversChild safetyBoysChildrenQualitative methodsDifficultiesExperienceCP interventionBehavioral Improvements but Limited Change in Callous-Unemotional Traits in Adolescents Treated for Conduct Problems
Thøgersen D, Elmose M, Viding E, McCrory E, Bjørnebekk G. Behavioral Improvements but Limited Change in Callous-Unemotional Traits in Adolescents Treated for Conduct Problems. Journal Of Child And Family Studies 2022, 31: 3342-3358. DOI: 10.1007/s10826-022-02435-6.Peer-Reviewed Original ResearchHigh CU traitsCU traitsBehavior problemsCo-occurring behavior problemsLatent growth curve model analysisParent-youth relationshipsElevated CU traitsCallous-unemotional traitsFunctional Family TherapyRule-breaking behaviorGrowth curve model analysisPotential moderation effectsProsocial skillsSocial skillsConduct problemsTreatment gainsRelational outcomesUnemotional TraitsMaternal supportFamily cohesionModeration effectBehavioral improvementFamily therapyBaseline anxietyAdolescentsSocial thinning and stress generation after childhood maltreatment: a neurocognitive social transactional model of psychiatric vulnerability
McCrory E, Foulkes L, Viding E. Social thinning and stress generation after childhood maltreatment: a neurocognitive social transactional model of psychiatric vulnerability. The Lancet Psychiatry 2022, 9: 828-837. PMID: 35926524, DOI: 10.1016/s2215-0366(22)00202-4.Peer-Reviewed Original ResearchConceptsTransactional modelChildhood maltreatmentNeurocognitive alterationsPsychiatric disordersQuantity of relationshipsIndividual's social networkSocial functioningSocial architecturePsychiatric vulnerabilityMaltreatmentSocial environmentExtant evidencePsychiatric riskNeurocognitive sequelaeSocial processesStress generationSocial networksDisordersPrescribing of antipsychotics among people with recorded personality disorder in primary care: a retrospective nationwide cohort study using The Health Improvement Network primary care database
Hardoon S, Hayes J, Viding E, McCrory E, Walters K, Osborn D. Prescribing of antipsychotics among people with recorded personality disorder in primary care: a retrospective nationwide cohort study using The Health Improvement Network primary care database. BMJ Open 2022, 12: e053943. PMID: 35264346, PMCID: PMC8968526, DOI: 10.1136/bmjopen-2021-053943.Peer-Reviewed Original ResearchConceptsSevere mental illnessPrimary care databasePersonality disorderSuch prescribingCohort studyCare databasePrimary careGeneral practiceHealth Improvement Network primary care databaseRetrospective nationwide cohort studyGeneral practice notesNationwide cohort studyRetrospective cohort studyGeneral practice recordsUK primary careCurrent UK guidelinesAdverse childhood experiencesMetabolic complicationsAntipsychotic prescribingAntipsychotic prescriptionsMedian timePractice recordsAntipsychoticsUK guidelinesClinical practiceSocial information use in adolescents with conduct problems and varying levels of callous‐unemotional traits
Gaule A, Bevilacqua L, Molleman L, Roberts R, van Duijvenvoorde A, van den Bos W, McCrory E, Viding E. Social information use in adolescents with conduct problems and varying levels of callous‐unemotional traits. JCPP Advances 2022, 2: e12067. PMID: 37431497, PMCID: PMC10242950, DOI: 10.1002/jcv2.12067.Peer-Reviewed Original ResearchSocial information useCallous-unemotional traitsConduct problemsSocial cognitionStrategy useSocial informationAtypical social cognitionInformation useSocial cognitive profileCP/HCUDegree of adjustmentBehavior management strategiesTD peersEmotional expressionAdolescents' estimatesSocial interactionAdolescentsSocial environmentSocial relationshipsCognitionPeersMore researchIQAttunementDifficultiesAltered reward and effort processing in children with maltreatment experience: a potential indicator of mental health vulnerability
Armbruster-Genç D, Valton V, Neil L, Vuong V, Freeman Z, Packer K, Kiffin M, Roiser J, Viding E, McCrory E. Altered reward and effort processing in children with maltreatment experience: a potential indicator of mental health vulnerability. Neuropsychopharmacology 2022, 47: 1063-1070. PMID: 35149765, PMCID: PMC8832084, DOI: 10.1038/s41386-022-01284-7.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingInternalizing symptomsHistory of maltreatmentAnterior cingulate cortexEffort processingEffort-based decision-making taskDecision-making taskEffort-based decisionElevated internalizing symptomsNon-maltreated childrenImpact of maltreatmentMental health vulnerabilitiesFuture internalizing symptomsNeural indicesACC activationAltered rewardBehavioral indicesMaltreatment experiencesLatent vulnerabilityCingulate cortexEffort sensitivityGroup differencesRewardMaltreatmentLongitudinal study
2021
Functional brain plasticity following childhood maltreatment: A longitudinal fMRI investigation of autobiographical memory processing.
Puetz V, Viding E, Maguire E, Mechelli A, Armbruster-Genç D, Sharp M, Rankin G, Gerin M, McCrory E. Functional brain plasticity following childhood maltreatment: A longitudinal fMRI investigation of autobiographical memory processing. Development And Psychopathology 2021, 35: 1382-1389. PMID: 34924093, DOI: 10.1017/s0954579421001292.Peer-Reviewed Original ResearchConceptsChildhood maltreatmentAutobiographical memory processingCortical midline structuresValenced cue wordsPotential developmental plasticityCue wordsMemory processingFMRI studyBOLD signal changesNeural functioningPsychological assessmentBrain networksMaltreatmentMidline structuresMaturational changesLongitudinal analysisProcessingSignal changesFMRIPsychopathologyRecallAdolescentsFunctioningWordsDevelopmental plasticityP.0780 Threat-based mechanisms underlying psychosis associated with developmental trauma: a behavioural study
Jung P, Bisby J, Greene T, McCrory E, Roiser J, David A, Bloomfield M. P.0780 Threat-based mechanisms underlying psychosis associated with developmental trauma: a behavioural study. European Neuropsychopharmacology 2021, 53: s569-s570. DOI: 10.1016/j.euroneuro.2021.10.843.Peer-Reviewed Original Research35.2 Trust and Childhood Maltreatment: Evidence of Bias in Appraisal of Unfamiliar Faces
Neil L, Viding E, Armbruster-Genc D, Lisi M, Mareschal I, Rankin G, Phillips H, Martin P, McCrory E. 35.2 Trust and Childhood Maltreatment: Evidence of Bias in Appraisal of Unfamiliar Faces. Journal Of The American Academy Of Child & Adolescent Psychiatry 2021, 60: s218. DOI: 10.1016/j.jaac.2021.09.276.Peer-Reviewed Original Research