2017
Dose-Volume Predictors of Esophagitis After Thoracic Stereotactic Body Radiation Therapy
Harder EM, Chen Z, Park HS, Mancini BR, Decker RH. Dose-Volume Predictors of Esophagitis After Thoracic Stereotactic Body Radiation Therapy. American Journal Of Clinical Oncology 2017, 40: 477-482. PMID: 26017483, DOI: 10.1097/coc.0000000000000195.Peer-Reviewed Original ResearchConceptsStepwise selection techniqueRadiation therapyThoracic stereotactic body radiation therapyStereotactic hypofractionated radiation therapyStereotactic body radiation therapyDose-volume predictorsNormal tissue complication probabilityHypofractionated radiation therapyMultivariate logistic regressionProbability estimatesBody radiation therapyPlanning target volumeEsophageal toxicityEsophagitis ratesCTCAE v4.0Dosimetric predictorsPulmonary tumorsInstitutional databaseRadiotherapy parametersPatterns of Dose Prescription and Recording in Stereotactic Body Radiation Therapy: A Multi-institutional Study
Das I, Andersen A, Bayliss A, Chen Z, Dimofte A, Huang L, Ai H, Langer M, Lee C, Popple R, Rice R, Schiff P, Zhu T. Patterns of Dose Prescription and Recording in Stereotactic Body Radiation Therapy: A Multi-institutional Study. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: s68-s69. DOI: 10.1016/j.ijrobp.2017.06.167.Peer-Reviewed Original Research
2016
State of dose prescription and compliance to international standard (ICRU-83) in intensity modulated radiation therapy among academic institutions
Das IJ, Andersen A, Chen Z, Dimofte A, Glatstein E, Hoisak J, Huang L, Langer MP, Lee C, Pacella M, Popple RA, Rice R, Smilowitz J, Sponseller P, Zhu T. State of dose prescription and compliance to international standard (ICRU-83) in intensity modulated radiation therapy among academic institutions. Practical Radiation Oncology 2016, 7: e145-e155. PMID: 28274405, DOI: 10.1016/j.prro.2016.11.003.Peer-Reviewed Original ResearchConceptsDose-volume histogramsDose prescriptionRadiation therapyHomogeneity indexICRU-83Stereotactic body radiation therapyBody radiation therapyTreatment sitesInstitutional review board clearanceLung sitesClinical trialsPelvic sitesPrescribed doseInternational guidelinesTumor siteArc therapyPatient treatmentTarget volumeTherapyPatientsDoseLevels of dosePrescriptionP-valueDose deliveryPulmonary dose-volume predictors of radiation pneumonitis following stereotactic body radiation therapy
Harder EM, Park HS, Chen Z, Decker RH. Pulmonary dose-volume predictors of radiation pneumonitis following stereotactic body radiation therapy. Practical Radiation Oncology 2016, 6: e353-e359. PMID: 27156424, DOI: 10.1016/j.prro.2016.01.015.Peer-Reviewed Original ResearchConceptsMean lung doseStereotactic body radiation therapyRisk of gradeRadiation pneumonitisMultivariable logistic regressionBody radiation therapyDosimetric predictorsRadiation therapyMaximum doseLogistic regressionRP rateBest dosimetric predictorCardiac dosimetric parametersDose-volume predictorsPercent of lungVolume of lungGross tumor volumeBackward stepwise eliminationLung V10Lung doseMean doseTotal lungUnivariate analysisPulmonary volumesTumor volume
2011
A novel modified dynamic conformal arc technique for treatment of peripheral lung tumors using stereotactic body radiation therapy
Ross CC, Kim JJ, Chen ZJ, Grew DJ, Chang BW, Decker RH. A novel modified dynamic conformal arc technique for treatment of peripheral lung tumors using stereotactic body radiation therapy. Practical Radiation Oncology 2011, 1: 126-134. PMID: 24673926, DOI: 10.1016/j.prro.2010.11.002.Peer-Reviewed Original ResearchNormal tissue dose constraintsStereotactic body radiation therapyBody radiation therapyDynamic conformal arc techniqueRadiation therapyDose constraintsNon-small cell lung cancerLung stereotactic body radiation therapyChest wall doseMedian lung V20RTOG 0236 protocolPeripheral lung tumorsCell lung cancerNormal tissue constraintsLower maximum doseTreatment volume coverageRTOG protocolInoperable patientsConsecutive patientsLung V20Lung doseLung cancerPTV coverageLung tumorsSeparate cohort