A 5‐HT2C receptor promoter polymorphism (HTR2C − 759C/T) is associated with obesity in women, and with resistance to weight loss in heterozygotes
Pooley EC, Fairburn CG, Cooper Z, Sodhi MS, Cowen PJ, Harrison PJ. A 5‐HT2C receptor promoter polymorphism (HTR2C − 759C/T) is associated with obesity in women, and with resistance to weight loss in heterozygotes. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2003, 126B: 124-127. PMID: 15048662, DOI: 10.1002/ajmg.b.20143.Peer-Reviewed Original ResearchConceptsObese womenWeight lossPromoter polymorphismNon-obese womenHigh triglyceride levelsInfluences weight lossAnti-obesity drugsRT-PCR studiesObese groupT statusTriglyceride levelsRisk factorsAntipsychotic drugsObesity trialsFrontal cortexPharmacogenetic testingSerotonin 5C subjectsBody weightC alleleWeight gainObesityT subjectsWomenPsychological treatmentWeight maintenance and relapse in obesity: a qualitative study
Byrne S, Cooper Z, Fairburn C. Weight maintenance and relapse in obesity: a qualitative study. International Journal Of Obesity 2003, 27: 955-962. PMID: 12861237, DOI: 10.1038/sj.ijo.0802305.Peer-Reviewed Original ResearchConceptsObese womenSuccessful weight maintainersSuccessful weight lossHealthy weight womenPsychological factorsDichotomous thinking styleWeight regainersWeight regainWeight maintainersWeight maintenanceStable weightWeight goalsWeight controlHealthy rangeProspective designWeight lossWomenCertain psychological factorsLack of vigilanceObesityRegainersLow weightThinking stylesStudy needQualitative study