1996
Life events, social support and marital relationships in the outcome of severe depression
Paykel ES, Cooper Z, Ramana R, Hayhurst H. Life events, social support and marital relationships in the outcome of severe depression. Psychological Medicine 1996, 26: 121-133. PMID: 8643751, DOI: 10.1017/s0033291700033766.Peer-Reviewed Original ResearchConceptsLife eventsSocial supportResidual symptomsSubsequent relapseSevere depressionRecurrent depressionPsychosocial factorsMilder depressionsRemissionPatient samplesSubsequent courseSubsequent outcomesDepressionRecent evidenceOutcomesLength of timeMarital relationshipSuch depressionMonthsRelapseSymptomsDepressive
1995
Remission and relapse in major depression: a two-year prospective follow-up study
Ramana R, Paykel ES, Cooper Z, Hayhurst H, Saxty M, Surtees PG. Remission and relapse in major depression: a two-year prospective follow-up study. Psychological Medicine 1995, 25: 1161-1170. PMID: 8637946, DOI: 10.1017/s0033291700033134.Peer-Reviewed Original ResearchConceptsTwo-year prospective followMajor depressive subjectsGreater initial severityProspective followLate recurrencePoor outcomeWorse outcomesInitial severityDepressive subjectsMajor depressionRemissionAdequate treatmentRelapseGreater severityMonthsLonger durationDepressionSeveritySubjectsOutcomesTreatmentRecurrenceCohortFollowIllnessResidual symptoms after partial remission: an important outcome in depression
Paykel ES, Ramana R, Cooper Z, Hayhurst H, Kerr J, Barocka A. Residual symptoms after partial remission: an important outcome in depression. Psychological Medicine 1995, 25: 1171-1180. PMID: 8637947, DOI: 10.1017/s0033291700033146.Peer-Reviewed Original ResearchConceptsResidual symptomsPartial remissionMajor depressionSevere initial illnessImportant adverse outcomesHamilton Depression ScaleTypical depressive symptomsInitial illnessEarly relapsePrior illnessAdverse outcomesIllness episodesDepression ScaleDrug treatmentLow doseDepressive symptomsSymptom presenceSymptomsRemissionDepressionWeak associationStrongest predictorIllnessMonthsImportant outcomes