2018
Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement
Yu T, Li Y, Fan F, Cao H, Luo X, Tan S, Yang F, Zhang X, Shugart YY, Hong LE, Li CR, Tan Y. Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement. Scientific Reports 2018, 8: 12884. PMID: 30150749, PMCID: PMC6110787, DOI: 10.1038/s41598-018-31186-y.Peer-Reviewed Original ResearchConceptsGray matter volumeAbnormal Involuntary Movement ScaleTardive dyskinesiaMatter volumeTD severityAntipsychotic medication treatmentCerebral morphological changesAbnormal involuntary movementsBrain structural magnetic resonance imagesPsychopathological symptomsNegative Syndrome ScaleNon-TD groupVoxel-based morphometryMedication treatmentHealthy controlsGMV changesMotor disordersAIMS scoresInvoluntary movementsMovement ScaleStructural magnetic resonance imagesTemporal cortexSchizophrenia patientsLingual gyrusSyndrome Scale
2013
Association of the dopamine β‐hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia
Zhou N, Yu Q, Li X, Yu Y, Kou C, Li W, Xu H, Luo X, Zuo L, Kosten TR, Zhang XY. Association of the dopamine β‐hydroxylase 19 bp insertion/deletion polymorphism with positive symptoms but not tardive dyskinesia in schizophrenia. Human Psychopharmacology Clinical And Experimental 2013, 28: 230-237. PMID: 23559427, DOI: 10.1002/hup.2311.Peer-Reviewed Original ResearchConceptsAbnormal Involuntary Movement ScaleTardive dyskinesiaPositive symptomsDel polymorphismSeverity of TDAIMS total scoreDel/del genotypeBp insertion/deletion polymorphismIns/ins genotypeNegative Syndrome ScaleSignificant differencesInsertion/deletion polymorphismConversion of dopamineIns/delSymptom subscoresChinese patientsTD patientsDopaminergic neurotransmissionHealthy controlsMovement ScaleDBH activityPatientsSyndrome ScaleDel genotypeTD severity