2023
Regional Homogeneity in schizophrenia patients with tardive dyskinesia: a resting-state fMRI study
Yu T, Li Y, Li N, Huang J, Fan F, Luo X, Tan S, Yang F, Tian B, Tian L, Li C, Tan Y. Regional Homogeneity in schizophrenia patients with tardive dyskinesia: a resting-state fMRI study. Psychiatry Research Neuroimaging 2023, 335: 111724. PMID: 37871408, DOI: 10.1016/j.pscychresns.2023.111724.Peer-Reviewed Original ResearchConceptsAbnormal Involuntary Movement ScaleTardive dyskinesiaInferior semilunar lobuleSchizophrenia patientsCourse of TDRegional homogeneityResting-state functional magnetic resonance imagingResting-state fMRI studySeverity of TDCerebral regional homogeneityUpper limb scoreNegative Syndrome ScaleNon-TD groupMedial frontal gyrusFunctional magnetic resonance imagingMagnetic resonance imagingLower ReHoReHo valuesHigher ReHoLimb scoreNeuronal degenerationHealthy controlsFunctional abnormalitiesMovement ScaleLeft supramarginal gyrus
2015
Mice lacking glutamate carboxypeptidase II develop normally, but are less susceptible to traumatic brain injury
Gao Y, Xu S, Cui Z, Zhang M, Lin Y, Cai L, Wang Z, Luo X, Zheng Y, Wang Y, Luo Q, Jiang J, Neale JH, Zhong C. Mice lacking glutamate carboxypeptidase II develop normally, but are less susceptible to traumatic brain injury. Journal Of Neurochemistry 2015, 134: 340-353. PMID: 25872793, DOI: 10.1111/jnc.13123.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryGlutamate carboxypeptidase IIModerate traumatic brain injuryNeurotransmitter N-acetylaspartylglutamateGCPII geneBrain injuryNervous systemSpatial learning/memoryEnhanced glutamate transmissionLong-term behavioral outcomesHippocampus 24 hInhibition of GCPIIWild-type littermatesMorris water mazeCarboxypeptidase IIKO mouse lineLearning/memoryHistopathological protectionGene KOBeam walkingGlutamate transmissionNeuronal degenerationAstrocyte damageKO miceNeurological behavior