2008
Human Endometrial Stem Cells Transplantation in a Parkinson's Disease Mouse Model.
Wolff E, Gao X, Andrews Z, Yao K, Du H, Taylor H. Human Endometrial Stem Cells Transplantation in a Parkinson's Disease Mouse Model. Biology Of Reproduction 2008, 78: 120-120. DOI: 10.1093/biolreprod/78.s1.120d.Peer-Reviewed Original ResearchDisease mouse modelParkinson's disease mouse modelTyrosine hydroxylaseNestin antibodyStriatal dopamineDopaminergic cellsDopaminergic pathwaysMouse modelMouse brainTherapeutic potentialNeurogenic differentiationWhole-cell patch-clamp recordingsCell patch-clamp recordingsPotassium channelsReproductive-aged womenStem cell transplantationBarium-sensitive potassium channelsDOPAC/dopamineDisease modelsNOD-SCID miceSensitive potassium channelsStem cellsParkinson's disease modelPyramidal cell bodiesPatch-clamp recordings
2002
Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP‐expressing locus coeruleus
van den Pol A, Ghosh PK, Liu R, Li Y, Aghajanian GK, Gao X. Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP‐expressing locus coeruleus. The Journal Of Physiology 2002, 541: 169-185. PMID: 12015428, PMCID: PMC2290314, DOI: 10.1113/jphysiol.2002.017426.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCarrier ProteinsCells, CulturedDose-Response Relationship, DrugElectrophysiologyFemaleGreen Fluorescent ProteinsImmunohistochemistryIn Vitro TechniquesIntracellular Signaling Peptides and ProteinsLocus CoeruleusLuminescent ProteinsMembrane PotentialsMiceMice, TransgenicMicroscopy, ConfocalNeuronsNeuropeptidesNeurotransmitter AgentsOrexinsPatch-Clamp TechniquesPregnancyTyrosine 3-MonooxygenaseConceptsLocus coeruleusHypocretin-1Mouse prion promoterGlutamate receptor antagonistsPresence of TTXImmunoreactive tyrosine hydroxylaseRat locus coeruleusNeonatal mouse brainPostnatal day 0Higher brain centersNew transgenic mouseSingle-unit recordingsInward cation currentMembrane potentialDual cell recordingsImproved cognitive performanceNoradrenergic neuronsLC neuronsHypocretin neuronsImmature neuronsPrion promoterReceptor antagonistMouse slicesTyrosine hydroxylaseExcitatory mechanisms