2016
Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities
Nadeau KJ, Anderson BJ, Berg EG, Chiang JL, Chou H, Copeland KC, Hannon TS, Huang T, Lynch JL, Powell J, Sellers E, Tamborlane WV, Zeitler P. Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities. Diabetes Care 2016, 39: 1635-1642. PMID: 27486237, PMCID: PMC5314694, DOI: 10.2337/dc16-1066.Peer-Reviewed Original ResearchConceptsType 2 diabetesConsensus reportYouth-Onset Type 2Current therapeutic optionsRisk of complicationsUnique pathophysiologyTherapeutic optionsIncreasing burdenVulnerable patientsAdult diseaseDiabetesType 2New treatmentsPsychosocial impactType 1Young adultsPrevention approachesTreatmentDiseaseAdultsChildrenAdvocacy groupsReportComplicationsPatients
2007
Degree of Obesity and Glucose Allostasis Are Major Effectors of Glucose Tolerance Dynamics in Obese Youth
Weiss R, Cali AM, Dziura J, Burgert TS, Tamborlane WV, Caprio S. Degree of Obesity and Glucose Allostasis Are Major Effectors of Glucose Tolerance Dynamics in Obese Youth. Diabetes Care 2007, 30: 1845-1850. PMID: 17475938, DOI: 10.2337/dc07-0325.Peer-Reviewed Original ResearchConceptsOral glucose tolerance testDegree of obesityElevated glucose levelsObese youthGlucose toleranceAmbient glycemiaInsulin sensitivityGlucose levelsSecond oral glucose tolerance testBaseline BMI z-scoreGlucose tolerance testBMI z-scoreAltered glucose metabolismCross-sectional analysisTolerance testInsulin sensitizationGlucose metabolismObesityZ-scoreLongitudinal assessmentLongitudinal changesMajor effectorGlycemiaSignificant reduction