2012
Characterization of Lipid Droplet and Its Regulation by Caveolin‐1 in Endothelial Cells
Kuo A, Zhang X, Harrison K, Sessa W. Characterization of Lipid Droplet and Its Regulation by Caveolin‐1 in Endothelial Cells. The FASEB Journal 2012, 26: 597.1-597.1. DOI: 10.1096/fasebj.26.1_supplement.597.1.Peer-Reviewed Original ResearchDeficient endothelial cellsCav-1Lipid dropletsFatty acid uptakeLD formationCaveolin-1Putative hairpin structureSurface of LDsCav-1 null miceIntegral membrane proteinsCellular energy homeostasisPotential physiological functionsAcid uptakeEndothelial cellsLD homeostasisUnique organellesCaveolae microdomainsMembrane proteinsKey cell typesDiacylglycerol acyltransferasesNovel functionPlasma membraneBiological processesIntracellular regulationPhysiological functions
2000
Direct Interaction between Endothelial Nitric-oxide Synthase and Dynamin-2 IMPLICATIONS FOR NITRIC-OXIDE SYNTHASE FUNCTION*
Cao S, Yao J, McCabe T, Yao Q, Katusic Z, Sessa W, Shah V. Direct Interaction between Endothelial Nitric-oxide Synthase and Dynamin-2 IMPLICATIONS FOR NITRIC-OXIDE SYNTHASE FUNCTION*. Journal Of Biological Chemistry 2000, 276: 14249-14256. PMID: 11120737, DOI: 10.1074/jbc.m006258200.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortaBlotting, WesternCalcimycinCattleCell LineDose-Response Relationship, DrugDynamin IDynaminsEndothelium, VascularGlutathione TransferaseGolgi ApparatusGTP PhosphohydrolasesIonophoresKineticsMicroscopy, ConfocalMicroscopy, FluorescenceNitric Oxide SynthaseNitric Oxide Synthase Type IIIPrecipitin TestsProtein BindingProtein BiosynthesisRatsRecombinant Fusion ProteinsTransfectionConceptsDynamin 2Bovine aortic endothelial cellsRecombinant eNOS proteinDirect protein-protein interactionDouble-label confocal immunofluorescenceProtein-protein interactionsSpecific protein interactionsDirect interactionClone 9 cellsEndothelial nitric oxide synthaseMembrane compartmentsLarge GTPaseGlutathione S-transferaseProtein interactionsNovel functionDynaminECV-304 cellsSynthase functionIntracellular signalsMembrane distributionConfocal immunofluorescenceFluorescent proteinENOS regulationGreen fluorescentProtein